Protein: KCC2
Calcium/calmodulin-dependent protein kinase II (EC 2.7.11.17)

Gene: KCC2, CMK2
Organism: Saccharomyces cerevisiae S288C
Interactions: 82
UniProt ID: P22517

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0004683 - calmodulin-dependent protein kinase activity
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

420228

CALM
Calmodulin

6

20

Small-scale

0.850

High

608774

EDE1
EH domain-containing and endocytosis protein 1

2

1

High-throughput

0.776

High

543218

HSC82
ATP-dependent molecular chaperone HSC82

2

18

High-throughput

0.754

High

409603

KAPC
cAMP-dependent protein kinase type 3

1

8

High-throughput

0.647

High

412947

KAPB
cAMP-dependent protein kinase type 2

1

8

High-throughput

0.647

High

434733

PBS2
MAP kinase kinase PBS2

1

17

High-throughput

0.647

High

549956

CSK21
Casein kinase II subunit alpha

1

16

High-throughput

0.647

High

562682

FUS3
Mitogen-activated protein kinase FUS3

1

20

High-throughput

0.647

High

565456

PHO85
Cyclin-dependent protein kinase PHO85

1

5

High-throughput

0.647

High

608762

STE11
Serine/threonine-protein kinase STE11

1

7

High-throughput

0.647

High

608769

KNS1
Dual specificity protein kinase KNS1

1

12

High-throughput

0.647

High

608820

YGK3
Glycogen synthase kinase-3 homolog YGK3

1

13

High-throughput

0.647

High

608821

PKH2
Serine/threonine-protein kinase PKH2

1

20

High-throughput

0.647

High

608771

HOG1
Mitogen-activated protein kinase HOG1

1

20

Small-scale

0.621

High

365813

HSP82
ATP-dependent molecular chaperone HSP82

1

18

High-throughput

0.618

High

608778

OPY1
Protein OPY1

1

0

High-throughput

0.614

High

608765

SYP1
Suppressor of yeast profilin deletion

2

1

High-throughput

0.601

High

608761

KCC2
Calcium/calmodulin-dependent protein kinase II

1

18

High-throughput

0.590

High

608766

NSR1
Nuclear localization sequence-binding protein

1

2

High-throughput

0.579

High

608783

AKR1
Palmitoyltransferase AKR1

1

2

High-throughput

0.579

High

608819

CMR3
Zinc finger protein CRM3

1

1

High-throughput

0.579

High

490370

HSP71
Heat shock protein SSA1

2

4

High-throughput

0.552

High

608768

XPO1
Exportin-1

1

8

High-throughput

0.536

High

593205

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

1

High-throughput

0.501

High

604291

MAG
DNA-3-methyladenine glycosylase

1

1

High-throughput

0.501

High

608763

DBR1
Lariat debranching enzyme

1

1

High-throughput

0.501

High

608772

PAH1
Phosphatidic acid phosphohydrolase 1

1

1

High-throughput

0.501

High

608773

GLRX4
Monothiol glutaredoxin-4

1

4

High-throughput

0.501

High

608784

TCPD
T-complex protein 1 subunit delta

1

1

High-throughput

0.501

High

608788

VFA1
VPS4-associated protein 1

1

1

High-throughput

0.501

High

608790

GPP1
Glycerol-1-phosphate phosphohydrolase 1

1

1

High-throughput

0.501

High

608795

LSM1
Sm-like protein LSm1

1

1

High-throughput

0.501

High

608797

MSN5
Protein MSN5

1

5

High-throughput

0.501

High

608798

PDK2
[Pyruvate dehydrogenase

1

3

High-throughput

0.501

High

608799

TBG
Tubulin gamma chain

1

6

High-throughput

0.501

High

608810

ASND1
Asparagine synthetase domain-containing protein YML096W

1

1

High-throughput

0.501

High

608816

SGT1
Protein SGT1

1

5

High-throughput

0.501

High

608775

MRP8
Uncharacterized protein MRP8

1

0

High-throughput

0.480

High

608776

YBS1
Uncharacterized protein YBR071W

1

0

High-throughput

0.480

High

608777

RFC5
Replication factor C subunit 5

1

0

High-throughput

0.480

High

608781

GRE3
NADPH-dependent aldose reductase GRE3

1

0

High-throughput

0.480

High

608786

VHR2
Transcription factor VHR2

1

0

High-throughput

0.480

High

608792

TDA10
Probable ATP-dependent kinase TDA10

1

0

High-throughput

0.480

High

608817

DSE3
Protein DSE3

1

0

High-throughput

0.480

High

608818

ATG29
Autophagy-related protein 29

1

0

High-throughput

0.480

High

608782

SDO1L
Restriction of telomere capping protein 3

1

1

Small-scale

0.479

High

608800

HST2
NAD-dependent protein deacetylase HST2

1

1

High-throughput

0.479

High

608801

GIS2
Zinc finger protein GIS2

1

1

High-throughput

0.479

High

608779

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.458

High

425541

RAD2
DNA repair protein RAD2

1

1

High-throughput

0.457

High

501156

HSF
Heat shock transcription factor

1

2

Small-scale

0.457

High

566707

ERS1
Cystine transporter

1

1

High-throughput

0.457

High

602305

DPOE
DNA polymerase epsilon catalytic subunit A

1

1

Small-scale

0.457

High

608785

OXA1
Mitochondrial inner membrane protein OXA1

1

1

High-throughput

0.457

High

608787

AVT6
Vacuolar amino acid transporter 6

1

8

High-throughput

0.457

High

608791

VATH
V-type proton ATPase subunit H

1

1

High-throughput

0.457

High

608794

RL17B
Large ribosomal subunit protein uL22B

1

1

High-throughput

0.457

High

608802

SPP1
COMPASS component SPP1

1

3

High-throughput

0.457

High

608803

PIR1
Cell wall mannoprotein PIR1

1

1

High-throughput

0.457

High

608813

JIP5
WD repeat-containing protein JIP5

1

1

High-throughput

0.457

High

608815

CDA1
Chitin deacetylase 1

1

1

High-throughput

0.457

High

367749

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.445

High

510294

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

608804

RLI1
Translation initiation factor RLI1

1

0

Small-scale

0.438

High

608767

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

608793

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

2

High-throughput

0.437

High

608814

URN1
Pre-mRNA-splicing factor URN1

1

1

High-throughput

0.437

High

342859

ENO2
Enolase 2

1

1

High-throughput

0.407

High

336712

SODM
Superoxide dismutase [Mn], mitochondrial

1

0

High-throughput

0.261

Low

608764

MRC1
Mediator of replication checkpoint protein 1

1

0

High-throughput

0.261

Low

608770

RM49
Large ribosomal subunit protein mL61

1

0

High-throughput

0.261

Low

608780

YB70
Uncharacterized membrane protein YBR220C

1

0

High-throughput

0.261

Low

608789

PP4R3
Serine/threonine-protein phosphatase 4 regulatory subunit 3

1

0

High-throughput

0.261

Low

608796

NET1
Nucleolar protein NET1

1

0

High-throughput

0.261

Low

608805

YMD7
Uncharacterized protein YML037C

1

0

High-throughput

0.261

Low

608806

NUP53
Nucleoporin NUP53

1

0

High-throughput

0.261

Low

608807

RIM13
Calpain-like protease 1

1

0

High-throughput

0.261

Low

608809

SYF1
Pre-mRNA-splicing factor SYF1

1

0

High-throughput

0.261

Low

608811

TVP18
Golgi apparatus membrane protein TVP18

1

0

High-throughput

0.261

Low

608812

ARPC3
Actin-related protein 2/3 complex subunit 3

1

0

High-throughput

0.261

Low

608808

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024