Protein: STDH
Catabolic L-serine/threonine dehydratase [Includes: L-serine dehydratase (EC 4.3.1.17) (L-serine deaminase); L-threonine dehydratase (EC 4.3.1.19) (L-threonine deaminase)]

Gene: STDH, CHA1
Organism: Saccharomyces cerevisiae S288C
Interactions: 100
UniProt ID: P25379

Gene Ontology (top 5):
GO:0003941 - L-serine ammonia-lyase activity
GO:0004794 - threonine deaminase activity
GO:0005739 - mitochondrion
GO:0006565 - L-serine catabolic process
GO:0006567 - threonine catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

343088

THDH
Threonine dehydratase, mitochondrial

1

20

High-throughput

0.618

High

630799

RCK1
Serine/threonine-protein kinase RCK1

2

3

Small-scale

0.543

High

630792

SPT7
Transcriptional activator SPT7

1

2

High-throughput

0.536

High

630818

BRE5
UBP3-associated protein BRE5

1

1

High-throughput

0.536

High

630809

SMK1
Sporulation-specific mitogen-activated protein kinase SMK1

1

4

High-throughput

0.500

High

630823

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

6

High-throughput

0.500

High

630777

XPO1
Exportin-1

1

1

High-throughput

0.489

High

630826

GCN5
Histone acetyltransferase GCN5

1

1

High-throughput

0.489

High

630778

NTH1
Endonuclease III homolog 1

1

0

High-throughput

0.479

High

341937

ATPB
ATP synthase subunit beta, mitochondrial

1

1

High-throughput

0.479

High

427185

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

1

High-throughput

0.479

High

477941

HSP77
Import motor subunit, mitochondrial

1

5

High-throughput

0.479

High

482102

RS18A
Small ribosomal subunit protein uS13A

1

2

High-throughput

0.479

High

543269

HSC82
ATP-dependent molecular chaperone HSC82

1

11

High-throughput

0.479

High

558567

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

1

High-throughput

0.479

High

587953

HSP60
Heat shock protein 60, mitochondrial

1

2

High-throughput

0.479

High

596613

ODO1
2-oxoglutarate dehydrogenase, mitochondrial

1

2

High-throughput

0.479

High

630774

COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial

1

1

High-throughput

0.479

High

630775

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

1

3

High-throughput

0.479

High

630787

PREP
Presequence protease, mitochondrial

1

1

High-throughput

0.479

High

630790

HSP78
Heat shock protein 78, mitochondrial

1

7

High-throughput

0.479

High

630793

MDJ1
DnaJ homolog 1, mitochondrial

1

3

High-throughput

0.479

High

630800

BCA1
Branched-chain-amino-acid aminotransferase, mitochondrial

1

1

High-throughput

0.479

High

630807

ALDH5
Aldehyde dehydrogenase 5, mitochondrial

1

3

High-throughput

0.479

High

630811

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

1

3

High-throughput

0.479

High

630814

ALAM
Probable alanine aminotransferase, mitochondrial

1

1

High-throughput

0.479

High

630821

NUM1
Nuclear migration protein NUM1

1

1

High-throughput

0.479

High

630831

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

13

High-throughput

0.479

High

336713

SODM
Superoxide dismutase [Mn], mitochondrial

1

0

High-throughput

0.458

High

423581

ADH3
Alcohol dehydrogenase 3, mitochondrial

1

0

High-throughput

0.458

High

452964

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

498635

RT01
Small ribosomal subunit protein mS43

1

0

High-throughput

0.458

High

567933

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

581263

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.458

High

602424

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

0

High-throughput

0.458

High

612925

AIM17
Probable oxidoreductase AIM17

1

0

High-throughput

0.458

High

630666

NFS1
Cysteine desulfurase, mitochondrial

1

0

High-throughput

0.458

High

630771

ILV6
Acetolactate synthase small subunit, mitochondrial

1

0

High-throughput

0.458

High

630772

KAD3
GTP:AMP phosphotransferase, mitochondrial

1

0

High-throughput

0.458

High

630781

RIM1
Single-stranded DNA-binding protein RIM1, mitochondrial

1

0

High-throughput

0.458

High

630782

ACPM
Acyl carrier protein, mitochondrial

1

0

High-throughput

0.458

High

630794

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.458

High

630798

GRPE
GrpE protein homolog, mitochondrial

1

0

High-throughput

0.458

High

630802

ILV3
Dihydroxy-acid dehydratase, mitochondrial

1

0

High-throughput

0.458

High

630806

OXA1
Mitochondrial inner membrane protein OXA1

1

0

High-throughput

0.458

High

630808

COQ7
5-demethoxyubiquinone hydroxylase, mitochondrial

1

0

High-throughput

0.458

High

630810

ETFB
Probable electron transfer flavoprotein subunit beta

1

0

High-throughput

0.458

High

630813

COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

1

0

High-throughput

0.458

High

630817

SUCA
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial

1

0

High-throughput

0.458

High

630822

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.458

High

630824

GLRX5
Monothiol glutaredoxin-5, mitochondrial

1

0

High-throughput

0.458

High

630838

ETFD
Probable electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial

1

0

High-throughput

0.458

High

630841

ETFA
Probable electron transfer flavoprotein subunit alpha, mitochondrial

1

0

High-throughput

0.458

High

409607

KAPC
cAMP-dependent protein kinase type 3

1

2

High-throughput

0.457

High

439630

SPS1
Sporulation-specific protein 1

1

2

High-throughput

0.457

High

630773

RFA2
Replication factor A protein 2

1

2

High-throughput

0.457

High

630784

MKK2
MAP kinase kinase MKK2/SSP33

1

4

High-throughput

0.457

High

630789

PRS6B
26S proteasome regulatory subunit 6B homolog

1

1

High-throughput

0.457

High

630805

RV167
Reduced viability upon starvation protein 167

1

3

High-throughput

0.457

High

357900

RS17A
Small ribosomal subunit protein eS17A

1

2

High-throughput

0.437

High

365857

HSP82
ATP-dependent molecular chaperone HSP82

1

11

High-throughput

0.437

High

406815

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.437

High

407748

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.437

High

557903

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

Small-scale

0.437

High

630776

TF2B
Transcription initiation factor IIB

1

5

High-throughput

0.437

High

630779

HS104
Heat shock protein 104

1

7

High-throughput

0.437

High

630783

HOG1
Mitogen-activated protein kinase HOG1

1

3

High-throughput

0.437

High

630788

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.437

High

630796

NU170
Nucleoporin NUP170

1

2

High-throughput

0.437

High

630804

LAA1
AP-1 accessory protein LAA1

1

3

High-throughput

0.437

High

630820

H3
Histone H3

1

1

High-throughput

0.437

High

630825

TOM1
E3 ubiquitin-protein ligase TOM1

1

1

High-throughput

0.437

High

630827

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

1

High-throughput

0.437

High

630828

RUVB1
RuvB-like protein 1

1

7

High-throughput

0.437

High

630832

TFC6
Transcription factor tau 91 kDa subunit

1

2

High-throughput

0.437

High

630836

MCA1
Metacaspase-1

1

1

High-throughput

0.437

High

630837

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.437

High

630840

RUVB2
RuvB-like protein 2

1

7

High-throughput

0.437

High

630785

HSP7F
Heat shock protein homolog SSE1

1

12

High-throughput

0.407

High

630801

SPT8
Transcription factor SPT8

1

1

High-throughput

0.407

High

630803

YM11
Uncharacterized protein YMR124W

1

1

High-throughput

0.407

High

630795

TAF5
Transcription initiation factor TFIID subunit 5

1

0

High-throughput

0.279

Low

630816

SDA1
Protein SDA1

1

0

High-throughput

0.269

Low

420471

RAD3
General transcription and DNA repair factor IIH helicase subunit XPD

1

0

High-throughput

0.261

Low

540210

PP2B2
Serine/threonine-protein phosphatase 2B catalytic subunit A2

1

0

High-throughput

0.261

Low

618753

PP2A1
Serine/threonine-protein phosphatase PP2A-1 catalytic subunit

1

0

High-throughput

0.261

Low

630780

ARP2
Actin-related protein 2

1

0

High-throughput

0.261

Low

630786

RAD24
Checkpoint protein RAD24

1

0

High-throughput

0.261

Low

630791

PP2C3
Protein phosphatase 2C homolog 3

1

0

High-throughput

0.261

Low

630797

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

0

High-throughput

0.261

Low

630812

LSM8
U6 snRNA-associated Sm-like protein LSm8

1

0

High-throughput

0.261

Low

630819

OCA2
Tyrosine-protein phosphatase-like protein OCA2

1

0

High-throughput

0.261

Low

630829

LCD1
DNA damage checkpoint protein LCD1

1

0

High-throughput

0.261

Low

630830

KU80
ATP-dependent DNA helicase II subunit 2

1

0

High-throughput

0.261

Low

630833

ASR1
Alcohol-sensitive RING finger protein 1

1

0

High-throughput

0.261

Low

630834

RBX1
RING-box protein HRT1

1

0

High-throughput

0.261

Low

630839

HRT3
F-box protein HRT3

1

0

High-throughput

0.261

Low

498807

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.249

Low

630815

CDH1
APC/C activator protein CDH1

1

0

Small-scale

0.249

Low

630835

SGO1
Shugoshin

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024