Protein: RL3
Large ribosomal subunit protein uL3 (50S ribosomal protein L3)

Gene: RL3, rplC
Organism: Escherichia coli K-12
Interactions: 144
UniProt ID: P60438

Gene Ontology (top 5):
GO:0000027 - ribosomal large subunit assembly
GO:0002181 - cytoplasmic translation
GO:0003735 - structural constituent of ribosome
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

462381

RS5
Small ribosomal subunit protein uS5

2

2

High-throughput

0.628

High

465438

CSPA
Cold shock protein CspA

2

11

High-throughput

0.612

High

467179

DBHB
DNA-binding protein HU-beta

2

2

High-throughput

0.612

High

739445

RLMN
Dual-specificity RNA methyltransferase RlmN

2

0

High-throughput

0.602

High

459999

RPPH
RNA pyrophosphohydrolase

2

0

High-throughput

0.585

High

463039

TIG
Trigger factor

2

1

Small-scale

0.570

High

459559

IF3
Translation initiation factor IF-3 [Cleaved into: Translation initiation factor IF-3, N-terminally processed; Translation initiation factor IF-3S]

2

0

High-throughput

0.563

High

368663

UVRD
DNA helicase II

1

2

High-throughput

0.536

High

415789

TOP1
DNA topoisomerase 1

1

1

High-throughput

0.536

High

459282

DNAK
Chaperone protein DnaK

1

4

High-throughput

0.536

High

459798

LPXA
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase

1

1

High-throughput

0.536

High

465694

RLUC
Ribosomal large subunit pseudouridine synthase C

1

2

High-throughput

0.536

High

466669

MENB
1,4-dihydroxy-2-naphthoyl-CoA synthase

1

1

High-throughput

0.536

High

469251

RL17
Large ribosomal subunit protein bL17

1

1

High-throughput

0.536

High

534560

SELB
Selenocysteine-specific elongation factor

1

4

High-throughput

0.536

High

542780

HELD
DNA helicase IV

1

2

High-throughput

0.536

High

599052

RNR
Ribonuclease R

1

2

High-throughput

0.536

High

599883

LPXD
UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase

1

1

High-throughput

0.536

High

608833

MUKB
Chromosome partition protein MukB

1

3

High-throughput

0.536

High

633787

MNME
tRNA modification GTPase MnmE

1

6

High-throughput

0.536

High

639424

RHLE
ATP-dependent RNA helicase RhlE

1

4

High-throughput

0.536

High

703333

AIDB
Putative acyl-CoA dehydrogenase AidB

1

1

High-throughput

0.536

High

738639

RSMB
Ribosomal RNA small subunit methyltransferase B

1

3

High-throughput

0.536

High

739463

CSPB
Cold shock-like protein CspB

1

11

High-throughput

0.536

High

741815

RLUB
Ribosomal large subunit pseudouridine synthase B

1

2

High-throughput

0.536

High

776574

ARFB
Peptidyl-tRNA hydrolase ArfB

1

1

High-throughput

0.536

High

889951

RL2
Large ribosomal subunit protein uL2

1

5

High-throughput

0.536

High

890028

MDH
Malate dehydrogenase

1

1

High-throughput

0.536

High

336975

PHSM
Maltodextrin phosphorylase

1

0

High-throughput

0.513

High

343731

SYW
Tryptophan--tRNA ligase

1

0

High-throughput

0.513

High

368584

DNAA
Chromosomal replication initiator protein DnaA

1

0

High-throughput

0.513

High

392895

EX7L
Exodeoxyribonuclease 7 large subunit

1

0

High-throughput

0.513

High

430839

SYL
Leucine--tRNA ligase

1

0

High-throughput

0.513

High

458403

HSLU
ATP-dependent protease ATPase subunit HslU

1

0

High-throughput

0.513

High

460190

HSLV
ATP-dependent protease subunit HslV

1

0

High-throughput

0.513

High

463416

UVRC
UvrABC system protein C

1

0

High-throughput

0.513

High

464045

YJGA
UPF0307 protein YjgA

1

0

High-throughput

0.513

High

468386

FKBX
FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.513

High

469638

TRKA
Trk system potassium uptake protein TrkA

1

0

High-throughput

0.513

High

489546

DPO3A
DNA polymerase III subunit alpha

1

0

High-throughput

0.513

High

599102

RNE
Ribonuclease E

1

0

High-throughput

0.513

High

612192

ISPA
Farnesyl diphosphate synthase

1

0

High-throughput

0.513

High

621065

PSS
CDP-diacylglycerol--serine O-phosphatidyltransferase

1

0

High-throughput

0.513

High

621868

ACCC
Biotin carboxylase

1

0

High-throughput

0.513

High

737117

CBPA
Curved DNA-binding protein

1

0

High-throughput

0.513

High

741739

RLMJ
Ribosomal RNA large subunit methyltransferase J

1

0

High-throughput

0.513

High

761630

PRMB
Ribosomal protein uL3 glutamine methyltransferase

1

0

High-throughput

0.513

High

761676

RSGA
Small ribosomal subunit biogenesis GTPase RsgA

1

0

High-throughput

0.513

High

890027

RISB
6,7-dimethyl-8-ribityllumazine synthase

1

0

High-throughput

0.513

High

890029

NFUA
Fe/S biogenesis protein NfuA

1

0

High-throughput

0.513

High

890034

GNGF
Putative gluconeogenesis factor

1

0

High-throughput

0.513

High

890036

RLMKL
Ribosomal RNA large subunit methyltransferase K/L [Includes: 23S rRNA m2G2445 methyltransferase

1

0

High-throughput

0.513

High

890042

DCYD
D-cysteine desulfhydrase

1

0

High-throughput

0.513

High

459732

KPRS
Ribose-phosphate pyrophosphokinase

1

1

High-throughput

0.500

High

439037

YCIH
Uncharacterized protein YciH

1

1

High-throughput

0.489

High

536271

TOP3
DNA topoisomerase 3

1

1

High-throughput

0.489

High

542962

SRLR
Glucitol operon repressor

1

1

High-throughput

0.489

High

659413

HOLB
DNA polymerase III subunit delta'

1

1

High-throughput

0.489

High

708179

YEJF
Uncharacterized ABC transporter ATP-binding protein YejF

1

1

High-throughput

0.489

High

458989

IHFA
Integration host factor subunit alpha

1

2

High-throughput

0.484

High

459019

IHFB
Integration host factor subunit beta

1

2

High-throughput

0.484

High

459507

IF2
Translation initiation factor IF-2

1

5

High-throughput

0.484

High

460023

NUSB
Transcription antitermination protein NusB

1

1

High-throughput

0.484

High

460130

IPYR
Inorganic pyrophosphatase

1

1

High-throughput

0.484

High

462694

RPOA
DNA-directed RNA polymerase subunit alpha

1

1

High-throughput

0.484

High

463537

RHLB
ATP-dependent RNA helicase RhlB

1

4

High-throughput

0.484

High

463592

SYT
Threonine--tRNA ligase

1

2

High-throughput

0.484

High

463903

RPOC
DNA-directed RNA polymerase subunit beta'

1

3

High-throughput

0.484

High

464316

CSPD
Cold shock-like protein CspD

1

11

High-throughput

0.484

High

464352

CSPE
Cold shock-like protein CspE

1

11

High-throughput

0.484

High

464368

CSPG
Cold shock-like protein CspG

1

11

High-throughput

0.484

High

464970

LON
Lon protease

1

1

High-throughput

0.484

High

465164

DEAD
ATP-dependent RNA helicase DeaD

1

4

High-throughput

0.484

High

465326

ULAR
HTH-type transcriptional regulator UlaR

1

1

High-throughput

0.484

High

465409

MREB
Cell shape-determining protein MreB

1

5

High-throughput

0.484

High

465485

CSPC
Cold shock-like protein CspC

1

11

High-throughput

0.484

High

466448

CLPA
ATP-dependent Clp protease ATP-binding subunit ClpA

1

4

High-throughput

0.484

High

468798

ODO1
2-oxoglutarate dehydrogenase E1 component

1

3

High-throughput

0.484

High

469664

YFIF
Uncharacterized tRNA/rRNA methyltransferase YfiF

1

3

High-throughput

0.484

High

469921

RLME
Ribosomal RNA large subunit methyltransferase E

1

3

High-throughput

0.484

High

888483

RAPA
RNA polymerase-associated protein RapA

1

4

High-throughput

0.484

High

889219

RSMH
Ribosomal RNA small subunit methyltransferase H

1

1

High-throughput

0.484

High

890026

RL4
Large ribosomal subunit protein uL4

1

3

High-throughput

0.484

High

890030

RLMB
23S rRNA

1

3

High-throughput

0.484

High

890031

CLPB
Chaperone protein ClpB

1

5

High-throughput

0.484

High

458321

CLPP
ATP-dependent Clp protease proteolytic subunit

1

0

High-throughput

0.464

High

458422

COAD
Phosphopantetheine adenylyltransferase

1

0

High-throughput

0.464

High

458544

DTD
D-aminoacyl-tRNA deacylase

1

0

High-throughput

0.464

High

458731

FABZ
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ

1

0

High-throughput

0.464

High

458757

FIS
DNA-binding protein Fis

1

0

High-throughput

0.464

High

458956

HFQ
RNA-binding protein Hfq

1

0

High-throughput

0.464

High

459034

HSLO
33 kDa chaperonin

1

0

High-throughput

0.464

High

459605

KDSA
2-dehydro-3-deoxyphosphooctonate aldolase

1

0

High-throughput

0.464

High

460302

PYRH
Uridylate kinase

1

0

High-throughput

0.464

High

462945

TGT
Queuine tRNA-ribosyltransferase

1

0

High-throughput

0.464

High

463459

YIHI
Der GTPase-activating protein YihI

1

0

High-throughput

0.464

High

464684

LDCI
Inducible lysine decarboxylase

1

0

High-throughput

0.464

High

464784

PHOL
PhoH-like protein

1

0

High-throughput

0.464

High

466050

YBCJ
Putative RNA-binding protein YbcJ

1

0

High-throughput

0.464

High

466324

ACCA
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha

1

0

High-throughput

0.464

High

467312

CRP
DNA-binding transcriptional dual regulator CRP

1

0

High-throughput

0.464

High

467788

YIBL
Uncharacterized protein YibL

1

0

High-throughput

0.464

High

468002

RL23
Large ribosomal subunit protein uL23

1

0

High-throughput

0.464

High

468758

NUSA
Transcription termination/antitermination protein NusA

1

0

High-throughput

0.464

High

469155

SPOT
Bifunctional

1

0

High-throughput

0.464

High

469189

RHO
Transcription termination factor Rho

1

0

High-throughput

0.464

High

469532

RPOH
RNA polymerase sigma factor RpoH

1

0

High-throughput

0.464

High

469700

YHBY
RNA-binding protein YhbY

1

0

High-throughput

0.464

High

483571

RCSB
Transcriptional regulatory protein RcsB

1

0

High-throughput

0.464

High

890032

HLDD
ADP-L-glycero-D-manno-heptose-6-epimerase

1

0

High-throughput

0.464

High

890033

NFI
Endonuclease V

1

0

High-throughput

0.464

High

469588

SSB
Single-stranded DNA-binding protein

1

1

High-throughput

0.445

High

421005

CCA
Multifunctional CCA protein [Includes: CCA-adding enzyme

1

0

High-throughput

0.279

Low

462810

SFSA
Sugar fermentation stimulation protein A

1

0

High-throughput

0.279

Low

468101

CAIF
Transcriptional activatory protein CaiF

1

0

High-throughput

0.279

Low

469512

SECD
Protein translocase subunit SecD

1

0

High-throughput

0.279

Low

621114

PRIC
Primosomal replication protein N''

1

0

High-throughput

0.279

Low

633812

RIBD
Riboflavin biosynthesis protein RibD [Includes: Diaminohydroxyphosphoribosylaminopyrimidine deaminase

1

0

High-throughput

0.279

Low

659418

HOLD
DNA polymerase III subunit psi

1

0

High-throughput

0.279

Low

661028

HOLC
DNA polymerase III subunit chi

1

0

High-throughput

0.279

Low

671977

GREB
Transcription elongation factor GreB

1

0

High-throughput

0.279

Low

713162

HOFQ
DNA utilization protein HofQ

1

0

High-throughput

0.279

Low

799699

YHFX
Uncharacterized protein YhfX

1

0

High-throughput

0.279

Low

807965

RTCB
RNA-splicing ligase RtcB

1

0

High-throughput

0.279

Low

852353

ABPB
Anti-bacteriophage protein B

1

0

High-throughput

0.279

Low

890035

YBJX
Uncharacterized protein YbjX

1

0

High-throughput

0.279

Low

890037

VXIS
Prophage excisionase-like protein

1

0

High-throughput

0.279

Low

890038

PAAX
Transcriptional repressor PaaX

1

0

High-throughput

0.279

Low

890039

RLHA
23S rRNA 5-hydroxycytidine C2501 synthase

1

0

High-throughput

0.279

Low

890040

MCBR
HTH-type transcriptional regulator McbR

1

0

High-throughput

0.279

Low

890041

YNEG
Uncharacterized protein YneG

1

0

High-throughput

0.279

Low

890043

LYSAC
Peptidyl-lysine N-acetyltransferase PatZ

1

0

High-throughput

0.279

Low

890044

DSBG
Thiol:disulfide interchange protein DsbG

1

0

High-throughput

0.279

Low

890045

MURR
HTH-type transcriptional regulator MurR

1

0

High-throughput

0.279

Low

890046

YGCP
Uncharacterized protein YgcP

1

0

High-throughput

0.279

Low

460095

PLSB
Glycerol-3-phosphate acyltransferase

1

0

High-throughput

0.253

Low

462626

RNPA
Ribonuclease P protein component

1

0

High-throughput

0.253

Low

463336

YACL
UPF0231 protein YacL

1

0

High-throughput

0.253

Low

463496

TRMB
tRNA

1

0

High-throughput

0.253

Low

464087

YBGC
Acyl-CoA thioester hydrolase YbgC

1

0

High-throughput

0.253

Low

467736

FIMB
Type 1 fimbriae regulatory protein FimB

1

0

High-throughput

0.253

Low

468106

CEDA
Cell division activator CedA

1

0

High-throughput

0.253

Low

468214

DCM
DNA-cytosine methyltransferase

1

0

High-throughput

0.253

Low

483590

RCSA
Transcriptional regulatory protein RcsA

1

0

High-throughput

0.253

Low


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Last updated: 15 Jul 2024