Protein: TIG
Trigger factor (TF) (EC 5.2.1.8) (PPIase)

Gene: TIG
Organism: Escherichia coli K-12
Interactions: 160
UniProt ID: P0A850

Gene Ontology (top 5):
GO:0003755 - peptidyl-prolyl cis-trans isomerase activity
GO:0005829 - cytosol
GO:0007049 - cell cycle
GO:0009408 - response to heat
GO:0015031 - protein transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

357024

RS7
Small ribosomal subunit protein uS7

2

1

Small-scale

0.776

High

462952

TIG
Trigger factor

2

0

Small-scale

0.716

High

459387

HTPG
Chaperone protein HtpG

1

0

High-throughput

0.656

High

462963

SLYD
FKBP-type peptidyl-prolyl cis-trans isomerase SlyD

1

0

High-throughput

0.656

High

462958

OMPA
Outer membrane protein A

3

0

Small-scale

0.632

High

462278

RS5
Small ribosomal subunit protein uS5

3

0

Small-scale

0.622

High

458682

FABA
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase

3

0

Small-scale

0.607

High

460940

RL28
Large ribosomal subunit protein bL28

3

0

Small-scale

0.607

High

463022

POTF
Putrescine-binding periplasmic protein PotF

1

0

High-throughput

0.586

High

461895

RS3
Small ribosomal subunit protein uS3

2

0

Small-scale

0.576

High

462449

RS9
Small ribosomal subunit protein uS9

2

0

Small-scale

0.576

High

462979

SDHA
Succinate dehydrogenase flavoprotein subunit

2

0

Small-scale

0.576

High

462987

RL14
Large ribosomal subunit protein uL14

2

0

Small-scale

0.576

High

462999

RL6
Large ribosomal subunit protein uL6

2

0

Small-scale

0.576

High

463044

RS21
Small ribosomal subunit protein bS21

2

0

Small-scale

0.576

High

463039

RL3
Large ribosomal subunit protein uL3

2

1

Small-scale

0.570

High

460238

PUR7
Phosphoribosylaminoimidazole-succinocarboxamide synthase

2

0

High-throughput

0.563

High

462969

GLNB
Nitrogen regulatory protein P-II 1

2

0

High-throughput

0.563

High

462980

HNS
DNA-binding protein H-NS

2

0

High-throughput

0.563

High

461347

RS11
Small ribosomal subunit protein uS11

2

0

Small-scale

0.547

High

463001

RS1
Small ribosomal subunit protein bS1

2

0

Small-scale

0.545

High

463040

RL4
Large ribosomal subunit protein uL4

2

0

Small-scale

0.545

High

449072

PFLB
Formate acetyltransferase 1

1

1

High-throughput

0.536

High

463051

GRE2
Probable dehydratase YbiW

1

1

High-throughput

0.536

High

461074

RL29
Large ribosomal subunit protein uL29

1

0

High-throughput

0.523

High

462989

RL23
Large ribosomal subunit protein uL23

1

0

High-throughput

0.523

High

404174

APAH
Bis(5'-nucleosyl)-tetraphosphatase [symmetrical]

1

0

High-throughput

0.517

High

367485

OMPF
Outer membrane porin F

1

0

High-throughput

0.513

High

421204

SDHB
Succinate dehydrogenase iron-sulfur subunit

1

0

High-throughput

0.513

High

452019

PUTA
Bifunctional protein PutA [Includes: Proline dehydrogenase

1

0

High-throughput

0.513

High

458295

CLPP
ATP-dependent Clp protease proteolytic subunit

1

0

High-throughput

0.513

High

462955

RPOC
DNA-directed RNA polymerase subunit beta'

1

0

High-throughput

0.513

High

462956

RPOB
DNA-directed RNA polymerase subunit beta

1

0

High-throughput

0.513

High

462962

G3P1
Glyceraldehyde-3-phosphate dehydrogenase A

1

0

High-throughput

0.513

High

462965

PTA
Phosphate acetyltransferase

1

0

High-throughput

0.513

High

462977

FLIT
Flagellar protein FliT

1

0

High-throughput

0.513

High

462993

ODP1
Pyruvate dehydrogenase E1 component

1

0

High-throughput

0.513

High

463008

NADE
NH(3)-dependent NAD(+) synthetase

1

0

High-throughput

0.513

High

463009

NARY
Respiratory nitrate reductase 2 beta chain

1

0

High-throughput

0.513

High

463010

NARZ
Respiratory nitrate reductase 2 alpha chain

1

0

High-throughput

0.513

High

463045

KAD
Adenylate kinase

1

0

High-throughput

0.513

High

463017

MAK
Fructokinase

1

1

High-throughput

0.500

High

463018

ACNA
Aconitate hydratase A

1

1

High-throughput

0.500

High

392863

RBSA
Ribose import ATP-binding protein RbsA

1

0

High-throughput

0.493

High

463005

RHSC
Protein RhsC

1

1

High-throughput

0.489

High

463006

RHSD
Protein RhsD

1

1

High-throughput

0.489

High

463012

KPYK2
Pyruvate kinase II

1

1

High-throughput

0.484

High

459469

IF2
Translation initiation factor IF-2

1

0

High-throughput

0.479

High

462985

EDD
Phosphogluconate dehydratase

1

0

High-throughput

0.479

High

457319

LEUC
3-isopropylmalate dehydratase large subunit

1

1

High-throughput

0.479

High

462984

KPYK1
Pyruvate kinase I

1

1

High-throughput

0.479

High

458174

CH10
Co-chaperonin GroES

1

0

High-throughput

0.464

High

458912

HFQ
RNA-binding protein Hfq

1

0

High-throughput

0.464

High

460111

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.464

High

462705

RPOZ
DNA-directed RNA polymerase subunit omega

1

0

High-throughput

0.464

High

462978

ASPA
Aspartate ammonia-lyase

1

0

High-throughput

0.464

High

462982

TDCA
HTH-type transcriptional regulator TdcA

1

0

High-throughput

0.464

High

462990

GLTJ
Glutamate/aspartate import permease protein GltJ

1

0

High-throughput

0.464

High

463032

PRMB
Ribosomal protein uL3 glutamine methyltransferase

1

0

High-throughput

0.464

High

337275

AAT
Aspartate aminotransferase

1

0

High-throughput

0.458

High

458510

UXAB
Altronate oxidoreductase

1

0

Small-scale

0.458

High

459897

NAGB
Glucosamine-6-phosphate deaminase

1

0

High-throughput

0.458

High

462954

YEEX
UPF0265 protein YeeX

1

0

High-throughput

0.458

High

462964

P5CR
Pyrroline-5-carboxylate reductase

1

0

High-throughput

0.458

High

462974

KBL
2-amino-3-ketobutyrate coenzyme A ligase

1

0

High-throughput

0.458

High

462975

CISY
Citrate synthase

1

0

High-throughput

0.458

High

462976

DPS
DNA protection during starvation protein

1

0

High-throughput

0.458

High

462983

YEBS
Intermembrane transport protein YebS

1

0

High-throughput

0.458

High

462995

GCH1L
GTP cyclohydrolase 1 type 2 homolog

1

0

High-throughput

0.458

High

463020

GLNE
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme

1

0

High-throughput

0.458

High

463021

PANB
3-methyl-2-oxobutanoate hydroxymethyltransferase

1

0

High-throughput

0.458

High

463029

GLF
UDP-galactopyranose mutase

1

0

High-throughput

0.458

High

463048

CSRA
Carbon storage regulator

1

0

High-throughput

0.458

High

462992

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex

1

1

Small-scale

0.445

High

463056

MAA
Maltose O-acetyltransferase

1

1

Small-scale

0.445

High

462779

METK
S-adenosylmethionine synthase

1

0

High-throughput

0.438

High

344059

CARB
Carbamoyl phosphate synthase large chain

1

0

Small-scale

0.426

High

415747

TOP1
DNA topoisomerase 1

1

0

Small-scale

0.426

High

447061

AVTA
Valine--pyruvate aminotransferase

1

0

Small-scale

0.426

High

457282

UVRA
UvrABC system protein A

1

0

Small-scale

0.426

High

457482

CARA
Carbamoyl phosphate synthase small chain

1

0

Small-scale

0.426

High

458835

GLK
Glucokinase

1

0

Small-scale

0.426

High

460417

RL10
Large ribosomal subunit protein uL10

1

0

Small-scale

0.426

High

460510

RL7
Large ribosomal subunit protein bL12

1

0

Small-scale

0.426

High

460733

RL1
Large ribosomal subunit protein uL1

1

0

Small-scale

0.426

High

461249

RS10
Small ribosomal subunit protein uS10

1

0

Small-scale

0.426

High

461611

RS19
Small ribosomal subunit protein uS19

1

0

Small-scale

0.426

High

462079

RS4
Small ribosomal subunit protein uS4

1

0

High-throughput

0.426

High

462581

RNC
Ribonuclease 3

1

0

Small-scale

0.426

High

462961

FTNA
Bacterial non-heme ferritin

1

0

Small-scale

0.426

High

462966

GATD
Galactitol 1-phosphate 5-dehydrogenase

1

0

Small-scale

0.426

High

462967

GLDA
Glycerol dehydrogenase

1

0

Small-scale

0.426

High

462970

RL13
Large ribosomal subunit protein uL13

1

0

Small-scale

0.426

High

462991

NUOE
NADH-quinone oxidoreductase subunit E

1

0

Small-scale

0.426

High

462994

PDXH
Pyridoxine/pyridoxamine 5'-phosphate oxidase

1

0

Small-scale

0.426

High

462997

RHO
Transcription termination factor Rho

1

0

Small-scale

0.426

High

462998

RL17
Large ribosomal subunit protein bL17

1

0

Small-scale

0.426

High

463002

PSTS
Phosphate-binding protein PstS

1

0

Small-scale

0.426

High

463003

YFIF
Uncharacterized tRNA/rRNA methyltransferase YfiF

1

0

Small-scale

0.426

High

463013

ASNB
Asparagine synthetase B [glutamine-hydrolyzing]

1

0

Small-scale

0.426

High

463014

TRMA
tRNA/tmRNA

1

0

Small-scale

0.426

High

463015

KITH
Thymidine kinase

1

0

Small-scale

0.426

High

463024

NUDC
NAD-capped RNA hydrolase NudC

1

0

Small-scale

0.426

High

463036

LUXS
S-ribosylhomocysteine lyase

1

0

Small-scale

0.426

High

463038

RL2
Large ribosomal subunit protein uL2

1

0

Small-scale

0.426

High

463041

RL22
Large ribosomal subunit protein uL22

1

0

Small-scale

0.426

High

463042

RL5
Large ribosomal subunit protein uL5

1

0

Small-scale

0.426

High

463046

MBHT
Hydrogenase-2 small chain

1

0

Small-scale

0.426

High

463047

PTKA
PTS system galactitol-specific EIIA component

1

0

Small-scale

0.426

High

463057

ISPD
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase

1

0

Small-scale

0.426

High

428544

THGA
Galactoside O-acetyltransferase

1

1

Small-scale

0.407

High

462981

CRA
Catabolite repressor/activator

1

1

Small-scale

0.407

High

463035

NANK
N-acetylmannosamine kinase

1

1

Small-scale

0.407

High

462972

HYPC
Hydrogenase maturation factor HypC

2

0

High-throughput

0.307

High

463043

YDIH
Uncharacterized protein YdiH

2

0

High-throughput

0.307

High

461734

RS2
Small ribosomal subunit protein uS2

2

0

Small-scale

0.297

High

340989

BGAL
Beta-galactosidase

1

0

High-throughput

0.279

Low

462953

UXAC
Uronate isomerase

1

0

High-throughput

0.279

Low

462971

FTSH
ATP-dependent zinc metalloprotease FtsH

1

0

High-throughput

0.279

Low

462973

YCGL
Protein YcgL

1

0

High-throughput

0.279

Low

462996

FOLM
Dihydromonapterin reductase

1

0

High-throughput

0.279

Low

463011

FADB
Fatty acid oxidation complex subunit alpha [Includes: Enoyl-CoA hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA isomerase/3-hydroxybutyryl-CoA epimerase

1

0

High-throughput

0.279

Low

463016

PPSA
Phosphoenolpyruvate synthase

1

0

High-throughput

0.279

Low

463027

EAEH
Putative attaching and effacing protein homolog

1

0

High-throughput

0.279

Low

463031

RSPA
Starvation-sensing protein RspA

1

0

High-throughput

0.279

Low

342294

DCDA
Diaminopimelate decarboxylase

1

0

High-throughput

0.253

Low

463023

ADEC
Adenine deaminase

1

0

High-throughput

0.253

Low

463052

SAD
Succinate semialdehyde dehydrogenase [NAD(P)+] Sad

1

0

High-throughput

0.253

Low

463053

YNIB
Uncharacterized protein YniB

1

0

High-throughput

0.253

Low

463058

TAPT
tRNA-uridine aminocarboxypropyltransferase

1

0

High-throughput

0.253

Low

367366

PBPA
Penicillin-binding protein 1A

1

0

High-throughput

0.249

Low

462957

BLC
Outer membrane lipoprotein Blc

1

0

High-throughput

0.249

Low

462959

RIMI
[Ribosomal protein bS18]-alanine N-acetyltransferase

1

0

High-throughput

0.249

Low

462960

GLPC
Anaerobic glycerol-3-phosphate dehydrogenase subunit C

1

0

High-throughput

0.249

Low

463019

LHR
Probable ATP-dependent helicase Lhr

1

0

High-throughput

0.249

Low

463028

YHJD
Inner membrane protein YhjD

1

0

High-throughput

0.249

Low

463030

WBBK
Putative glycosyltransferase WbbK

1

0

High-throughput

0.249

Low

463033

YJDJ
Uncharacterized protein YjdJ

1

0

High-throughput

0.249

Low

463037

CSIE
Stationary phase-inducible protein CsiE

1

0

High-throughput

0.249

Low

463049

PXPA
5-oxoprolinase subunit A

1

0

High-throughput

0.249

Low

463050

RLMF
Ribosomal RNA large subunit methyltransferase F

1

0

High-throughput

0.249

Low

463055

GLSA1
Glutaminase 1

1

0

High-throughput

0.249

Low

463059

YAFV
Omega-amidase YafV

1

0

High-throughput

0.249

Low

458765

FLGH
Flagellar L-ring protein

1

0

High-throughput

0.238

Low

463034

EPMB
L-lysine 2,3-aminomutase

1

0

High-throughput

0.238

Low

340772

AK1H
Bifunctional aspartokinase/homoserine dehydrogenase 1

1

0

Small-scale

0.232

Low

358363

RL15
Large ribosomal subunit protein uL15

1

0

Small-scale

0.232

Low

403501

FPG
Formamidopyrimidine-DNA glycosylase

1

0

Small-scale

0.232

Low

421062

HIS7
Histidine biosynthesis bifunctional protein HisB [Includes: Histidinol-phosphatase

1

0

Small-scale

0.232

Low

458437

DADA
D-amino acid dehydrogenase

1

0

Small-scale

0.232

Low

462968

MREB
Cell shape-determining protein MreB

1

0

Small-scale

0.232

Low

462986

FABY
Probable acyltransferase FabY

1

0

Small-scale

0.232

Low

462988

RL16
Large ribosomal subunit protein uL16

1

0

Small-scale

0.232

Low

463000

RS14
Small ribosomal subunit protein uS14

1

0

Small-scale

0.232

Low

463004

GATZ
D-tagatose-1,6-bisphosphate aldolase subunit GatZ

1

0

Small-scale

0.232

Low

463007

ARGD
Acetylornithine/succinyldiaminopimelate aminotransferase

1

0

Small-scale

0.232

Low

463025

OPGG
Glucans biosynthesis protein G

1

0

Small-scale

0.232

Low

463026

CBPA
Curved DNA-binding protein

1

0

Small-scale

0.232

Low

463054

A2MGH
Putative alpha-2-macroglobulin homolog

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024