Protein: HXKG
Glucokinase-1 (EC 2.7.1.2) (Glucose kinase 1) (GLK-1)

Gene: HXKG, GLK1
Organism: Saccharomyces cerevisiae S288C
Interactions: 94
UniProt ID: P17709

Gene Ontology (top 5):
GO:0001678 - intracellular glucose homeostasis
GO:0004340 - glucokinase activity
GO:0005524 - ATP binding
GO:0005536 - D-glucose binding
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

570663

HXKG
Glucokinase-1

2

12

Small-scale

0.786

High

570721

EMI2
Putative glucokinase-2

2

12

High-throughput

0.743

High

570673

HS104
Heat shock protein 104

2

5

Small-scale

0.584

High

570705

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

2

High-throughput

0.584

High

510183

SSB1
Ribosome-associated molecular chaperone SSB1

2

11

High-throughput

0.571

High

570666

SIS1
Protein SIS1

2

5

High-throughput

0.571

High

524150

CAF20
Cap-associated protein CAF20

2

2

High-throughput

0.543

High

570725

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

2

1

High-throughput

0.543

High

570717

IMA1
Importin subunit alpha

1

1

High-throughput

0.541

High

431338

LTE1
Guanine nucleotide exchange factor LTE1

1

1

High-throughput

0.536

High

477112

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

3

High-throughput

0.501

High

570702

BNI1
Protein BNI1

1

1

High-throughput

0.501

High

339423

CDK1
Cyclin-dependent kinase 1

1

2

High-throughput

0.500

High

389623

DNLI1
DNA ligase 1

1

1

High-throughput

0.500

High

570671

HRR25
Casein kinase I homolog HRR25

1

2

High-throughput

0.500

High

570672

RAD16
DNA repair protein RAD16

1

2

High-throughput

0.500

High

570676

GYP6
GTPase-activating protein GYP6

1

1

High-throughput

0.500

High

570682

TCTP
Translationally-controlled tumor protein homolog

1

2

High-throughput

0.500

High

570683

YPT10
GTP-binding protein YPT10

1

4

High-throughput

0.500

High

570688

RIM11
Serine/threonine-protein kinase RIM11/MSD1

1

4

High-throughput

0.500

High

570689

RCK1
Serine/threonine-protein kinase RCK1

1

5

High-throughput

0.500

High

570696

RV167
Reduced viability upon starvation protein 167

1

2

High-throughput

0.500

High

570697

AFG3
Mitochondrial inner membrane m-AAA protease component YTA10

1

3

High-throughput

0.500

High

570700

TBP6
Probable 26S proteasome subunit YTA6

1

3

High-throughput

0.500

High

570707

PPT1
Serine/threonine-protein phosphatase T

1

6

High-throughput

0.500

High

570710

SIW14
Inositol phosphatase SIW14

1

2

High-throughput

0.500

High

570715

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

3

High-throughput

0.500

High

570722

KU80
ATP-dependent DNA helicase II subunit 2

1

1

High-throughput

0.500

High

570730

MLH3
DNA mismatch repair protein MLH3

1

1

High-throughput

0.500

High

570732

YP150
Putative serine/threonine-protein kinase YPL150W

1

1

High-throughput

0.500

High

570734

ATG5
Autophagy protein 5

1

2

High-throughput

0.500

High

570714

TPS1
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit

1

0

High-throughput

0.493

High

570675

TOR2
Serine/threonine-protein kinase TOR2

1

1

High-throughput

0.481

High

570681

TOR1
Serine/threonine-protein kinase TOR1

1

1

High-throughput

0.481

High

570691

KOG1
Target of rapamycin complex 1 subunit KOG1

1

1

High-throughput

0.481

High

416278

SIR3
Regulatory protein SIR3

1

0

High-throughput

0.479

High

420544

SPT2
Protein SPT2

1

0

High-throughput

0.479

High

523335

SRS2
ATP-dependent DNA helicase SRS2

1

0

High-throughput

0.479

High

570679

MED9
Mediator of RNA polymerase II transcription subunit 9

1

0

High-throughput

0.479

High

570694

PEX7
Peroxisomal targeting signal 2 receptor

1

0

High-throughput

0.479

High

570701

RFC4
Replication factor C subunit 4

1

0

High-throughput

0.479

High

570720

POLH
DNA polymerase eta

1

0

High-throughput

0.479

High

340007

KPYK1
Pyruvate kinase 1

1

2

Small-scale

0.479

High

365752

HSP82
ATP-dependent molecular chaperone HSP82

1

7

High-throughput

0.479

High

543145

HSC82
ATP-dependent molecular chaperone HSC82

1

7

High-throughput

0.479

High

570665

RAD53
Serine/threonine-protein kinase RAD53

1

1

High-throughput

0.479

High

570677

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

570678

PRS6A
26S proteasome regulatory subunit 6A

1

2

High-throughput

0.479

High

570692

RPN10
26S proteasome regulatory subunit RPN10

1

1

High-throughput

0.479

High

570698

RSP5
E3 ubiquitin-protein ligase RSP5

1

2

High-throughput

0.479

High

570706

KPYK2
Pyruvate kinase 2

1

2

High-throughput

0.479

High

570711

SAM50
Sorting assembly machinery 50 kDa subunit

1

2

High-throughput

0.479

High

570716

MCE1
mRNA-capping enzyme subunit alpha

1

0

High-throughput

0.458

High

570719

ESP1
Separin

1

0

High-throughput

0.458

High

570712

ACT
Actin

1

1

Small-scale

0.457

High

399320

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.457

High

419296

HAP2
Transcriptional activator HAP2

1

1

High-throughput

0.457

High

550513

PCNA
Proliferating cell nuclear antigen

1

2

High-throughput

0.457

High

570664

PRP6
Pre-mRNA-splicing factor 6

1

3

High-throughput

0.457

High

570667

CDC10
Cell division control protein 10

1

2

High-throughput

0.457

High

570669

RFA3
Replication factor A protein 3

1

1

High-throughput

0.457

High

570674

PP12
Serine/threonine-protein phosphatase PP1-2

1

4

High-throughput

0.457

High

570680

PPZ2
Serine/threonine-protein phosphatase PP-Z2

1

4

High-throughput

0.457

High

570685

PLPHP
Pyridoxal phosphate homeostasis protein

1

1

High-throughput

0.457

High

570687

SHE3
SWI5-dependent HO expression protein 3

1

1

High-throughput

0.457

High

570693

TEM1
Protein TEM1

1

4

High-throughput

0.457

High

570695

SWD1
COMPASS component SWD1

1

3

High-throughput

0.457

High

570703

SKP2
F-box protein SKP2

1

1

High-throughput

0.457

High

570704

MOB2
CBK1 kinase activator protein MOB2

1

1

High-throughput

0.457

High

570709

CWC22
Pre-mRNA-splicing factor CWC22

1

1

High-throughput

0.457

High

570713

CDC14
Tyrosine-protein phosphatase CDC14

1

1

High-throughput

0.457

High

570724

SEN15
tRNA-splicing endonuclease subunit SEN15

1

1

High-throughput

0.457

High

570733

RAD59
DNA repair protein RAD59

1

1

High-throughput

0.457

High

490264

HSP71
Heat shock protein SSA1

1

10

High-throughput

0.445

High

493135

HSP72
Heat shock protein SSA2

1

10

High-throughput

0.445

High

570699

SSB2
Ribosome-associated molecular chaperone SSB2

1

11

High-throughput

0.445

High

570727

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

3

High-throughput

0.445

High

570670

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

570684

NU170
Nucleoporin NUP170

1

2

High-throughput

0.437

High

570690

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.437

High

570729

AP3D
AP-3 complex subunit delta

1

2

High-throughput

0.437

High

570731

RRP6
Exosome complex exonuclease RRP6

1

5

High-throughput

0.437

High

425289

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.279

Low

356229

H4
Histone H4

1

0

High-throughput

0.269

Low

570735

NOP58
Nucleolar protein 58

1

0

High-throughput

0.269

Low

396172

ARGR2
Arginine metabolism regulation protein II

1

0

High-throughput

0.265

Low

570686

FIG1
Factor-induced gene 1 protein

1

0

High-throughput

0.265

Low

570728

ESA1
Histone acetyltransferase ESA1

1

0

Small-scale

0.261

Low

570708

YGI1
Uncharacterized protein YGL081W

1

0

High-throughput

0.261

Low

570718

UTP17
NET1-associated nuclear protein 1

1

0

High-throughput

0.261

Low

570723

ERB1
Ribosome biogenesis protein ERB1

1

0

High-throughput

0.261

Low

570668

YCE6
Putative uncharacterized protein YCL046W

1

0

High-throughput

0.249

Low

570726

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024