Protein: SPA2
Protein SPA2

Gene: SPA2
Organism: Saccharomyces cerevisiae S288C
Interactions: 76
UniProt ID: P23201

Gene Ontology (top 5):
GO:0000131 - incipient cellular bud site
GO:0000133 - polarisome
GO:0005078 - MAP-kinase scaffold activity
GO:0005826 - actomyosin contractile ring
GO:0005934 - cellular bud tip

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

613036

SPA2
Protein SPA2

4

14

Small-scale

0.902

High

613061

PEA2
Protein PEA2

7

0

Small-scale

0.715

High

613071

GYP3
GTPase-activating protein GYP3

3

2

Small-scale

0.658

High

585254

MYO2
Myosin-2

3

5

Small-scale

0.642

High

613091

MSB4
GTPase-activating protein MSB4

3

2

Small-scale

0.641

High

613078

SLT2
Mitogen-activated protein kinase SLT2/MPK1

3

9

Small-scale

0.637

High

613057

YM11
Uncharacterized protein YMR124W

3

0

Small-scale

0.636

High

613046

MKK1
MAP kinase kinase MKK1/SSP32

2

10

Small-scale

0.625

High

613064

BUD6
Bud site selection protein 6

2

1

Small-scale

0.619

High

613055

KEL1
Kelch repeat-containing protein 1

2

5

High-throughput

0.613

High

446114

MYO1
Myosin-1

2

5

Small-scale

0.584

High

613081

CYK2
Cytokinesis protein 2

1

5

Small-scale

0.573

High

613045

IMB3
Importin subunit beta-3

2

2

High-throughput

0.567

High

339446

CDK1
Cyclin-dependent kinase 1

1

5

High-throughput

0.561

High

613065

BNI1
Protein BNI1

1

3

Small-scale

0.552

High

535979

CHS2
Chitin synthase 2

1

0

Small-scale

0.549

High

613082

CYK3
Cytokinesis protein 3

1

0

Small-scale

0.549

High

613080

TOM1
E3 ubiquitin-protein ligase TOM1

2

8

High-throughput

0.549

High

613068

YFI6
Uncharacterized protein YFR016C

2

13

Small-scale

0.543

High

613058

BEM2
GTPase-activating protein BEM2/IPL2

1

2

High-throughput

0.515

High

420011

STE7
Serine/threonine-protein kinase STE7

1

14

Small-scale

0.508

High

613037

STE11
Serine/threonine-protein kinase STE11

1

3

Small-scale

0.508

High

613047

MKK2
MAP kinase kinase MKK2/SSP33

1

10

Small-scale

0.508

High

613060

FIR1
Factor interacting with REF2

1

0

Small-scale

0.504

High

613049

HSP7F
Heat shock protein homolog SSE1

2

12

High-throughput

0.504

High

613076

ACT
Actin

1

10

Small-scale

0.501

High

613042

XPO1
Exportin-1

1

1

High-throughput

0.489

High

613083

SHS1
Seventh homolog of septin 1

1

0

Small-scale

0.486

High

613041

BEM1
Bud emergence protein 1

1

18

Small-scale

0.481

High

613079

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

8

High-throughput

0.481

High

562683

FUS3
Mitogen-activated protein kinase FUS3

1

8

Small-scale

0.479

High

605482

DBF2
Cell cycle protein kinase DBF2

1

12

High-throughput

0.479

High

613048

PAN1
Actin cytoskeleton-regulatory complex protein PAN1

1

12

Small-scale

0.479

High

613073

SSK2
MAP kinase kinase kinase SSK2

1

8

Small-scale

0.479

High

613089

IQG1
Ras GTPase-activating-like protein IQG1

1

6

Small-scale

0.479

High

613092

LAS17
Proline-rich protein LAS17

1

8

Small-scale

0.479

High

613050

MRE11
Double-strand break repair protein MRE11

1

2

High-throughput

0.470

High

613063

NDC80
Kinetochore protein NDC80

1

9

High-throughput

0.464

High

613067

SMD3
Small nuclear ribonucleoprotein Sm D3

1

1

High-throughput

0.464

High

613066

SPR3
Sporulation-regulated protein 3

1

0

High-throughput

0.460

High

613074

INN1
Ingression protein 1

1

0

Small-scale

0.458

High

561845

TUP1
General transcriptional corepressor TUP1

1

11

High-throughput

0.439

High

613043

ZIP1
Synaptonemal complex protein ZIP1

1

4

High-throughput

0.439

High

613056

IFH1
Protein IFH1

1

8

High-throughput

0.439

High

613075

NST1
Stress response protein NST1

1

9

High-throughput

0.439

High

613093

RLF2
Chromatin assembly factor 1 subunit p90

1

4

High-throughput

0.439

High

479931

RS6A
Small ribosomal subunit protein eS6A

1

2

High-throughput

0.437

High

543223

HSC82
ATP-dependent molecular chaperone HSC82

1

5

High-throughput

0.437

High

557884

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

High-throughput

0.437

High

613038

BPH1
Beige protein homolog 1

1

5

High-throughput

0.437

High

613044

HS104
Heat shock protein 104

1

1

Small-scale

0.437

High

613051

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

5

High-throughput

0.437

High

613054

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

3

Small-scale

0.437

High

613062

SSB2
Ribosome-associated molecular chaperone SSB2

1

11

High-throughput

0.437

High

613072

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.437

High

613077

H3
Histone H3

1

20

High-throughput

0.437

High

613085

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.437

High

613086

AP3D
AP-3 complex subunit delta

1

4

High-throughput

0.437

High

613090

SMT3
Ubiquitin-like protein SMT3

1

5

High-throughput

0.437

High

526781

CG13
G1/S-specific cyclin CLN3

1

2

High-throughput

0.417

High

449914

HSP73
Heat shock protein SSA3

1

11

High-throughput

0.407

High

493234

HSP72
Heat shock protein SSA2

1

11

High-throughput

0.407

High

613039

MAS5
Mitochondrial protein import protein MAS5

1

6

High-throughput

0.407

High

613059

HSP7E
Heat shock protein SSC3, mitochondrial

1

11

High-throughput

0.407

High

613053

CND2
Condensin complex subunit 2

1

0

Small-scale

0.279

Low

345228

ATIF
F(1)-ATPase inhibitor IF(1), mitochondrial

1

0

High-throughput

0.265

Low

613084

SGO1
Shugoshin

1

0

High-throughput

0.251

Low

613087

SRL2
Protein SRL2

1

0

High-throughput

0.251

Low

406799

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.249

Low

407735

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.249

Low

613040

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

613052

PDR5
Pleiotropic ABC efflux transporter of multiple drugs

1

0

Small-scale

0.249

Low

613069

MNN11
Probable alpha-1,6-mannosyltransferase MNN11

1

0

Small-scale

0.249

Low

613070

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.249

Low

613088

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024