Protein: MDN1
Midasin (Dynein-related AAA-ATPase REA1) (MIDAS-containing protein) (Ribosome export/assembly protein 1)

Gene: MDN1
Organism: Saccharomyces cerevisiae S288C
Interactions: 128
UniProt ID: Q12019

Gene Ontology (top 5):
GO:0000027 - ribosomal large subunit assembly
GO:0000055 - ribosomal large subunit export from nucleus
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

630897

NLE1
Ribosome assembly protein 4

7

20

Small-scale

0.749

High

766726

NUG1
Nuclear GTP-binding protein NUG1

7

5

Small-scale

0.740

High

864702

NOG2
Nucleolar GTP-binding protein 2

7

5

Small-scale

0.740

High

860908

PESC
Pescadillo homolog

7

1

Small-scale

0.739

High

756885

RIX1
Pre-rRNA-processing protein RIX1

9

0

Small-scale

0.721

High

977783

ARX1
Probable metalloprotease ARX1

6

0

Small-scale

0.695

High

866283

NOP15
Ribosome biogenesis protein 15

4

2

High-throughput

0.691

High

861415

SDA1
Protein SDA1

4

1

Small-scale

0.687

High

754218

CIC1
Proteasome-interacting protein CIC1

4

1

High-throughput

0.686

High

1014855

YTM1
Ribosome biogenesis protein YTM1

3

20

Small-scale

0.665

High

993176

BUD20
Bud site selection protein 20

4

0

Small-scale

0.664

High

755263

IPI1
Pre-rRNA-processing protein IPI1

4

0

Small-scale

0.660

High

973480

NOG1
Nucleolar GTP-binding protein 1

3

3

High-throughput

0.656

High

1014854

MDN1
Midasin

1

19

Small-scale

0.647

High

865687

IPI3
Pre-rRNA-processing protein IPI3

3

12

Small-scale

0.646

High

356778

H4
Histone H4

2

12

High-throughput

0.621

High

742085

NOP4
Nucleolar protein 4

2

1

High-throughput

0.621

High

681064

HS104
Heat shock protein 104

1

4

High-throughput

0.618

High

1014856

NOP53
Ribosome biogenesis protein NOP53

3

0

Small-scale

0.613

High

638888

SPB4
ATP-dependent rRNA helicase SPB4

2

3

High-throughput

0.584

High

776539

RLP7
Ribosome biogenesis protein RLP7

2

1

High-throughput

0.584

High

535150

RL3
Large ribosomal subunit protein uL3

2

0

Small-scale

0.559

High

703136

MRT4
Ribosome assembly factor MRT4

2

0

Small-scale

0.559

High

859988

CGR1
rRNA-processing protein CGR1

2

0

Small-scale

0.559

High

495219

HSP72
Heat shock protein SSA2

2

10

High-throughput

0.552

High

698013

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

2

High-throughput

0.541

High

424758

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.536

High

454669

TBA3
Tubulin alpha-3 chain

1

3

High-throughput

0.536

High

611040

ESS1
Peptidyl-prolyl cis-trans isomerase ESS1

1

1

High-throughput

0.536

High

731022

MAOM
NAD-dependent malic enzyme, mitochondrial

1

1

High-throughput

0.536

High

752887

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.536

High

763194

FHP
Flavohemoprotein

1

4

High-throughput

0.536

High

809815

NMD5
Nonsense-mediated mRNA decay protein 5

1

2

High-throughput

0.536

High

857285

ACS2
Acetyl-coenzyme A synthetase 2

1

1

High-throughput

0.536

High

994549

RBX1
RING-box protein HRT1

1

7

High-throughput

0.536

High

979118

RRB1
Ribosome assembly protein RRB1

1

16

High-throughput

0.515

High

498613

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.513

High

533955

INO4
Protein INO4

1

0

High-throughput

0.513

High

703862

PRS6B
26S proteasome regulatory subunit 6B homolog

1

0

High-throughput

0.513

High

744291

TBS1
Uncharacterized transcriptional regulatory protein TBS1

1

0

High-throughput

0.493

High

361068

TBB
Tubulin beta chain

1

4

High-throughput

0.489

High

1014861

HSP42
Heat shock protein 42

1

2

High-throughput

0.489

High

710836

CASP
Protein CASP

1

18

High-throughput

0.481

High

728775

BDF1
Bromodomain-containing factor 1

1

20

High-throughput

0.481

High

339891

CDK1
Cyclin-dependent kinase 1

1

14

High-throughput

0.479

High

342789

ENO1
Enolase 1

1

4

High-throughput

0.479

High

558308

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.479

High

628563

SIS1
Protein SIS1

1

8

High-throughput

0.479

High

632137

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

634464

SPB1
27S pre-rRNA

1

8

High-throughput

0.479

High

663589

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

698191

AFG2
ATPase family gene 2 protein

1

4

High-throughput

0.479

High

698971

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

7

High-throughput

0.479

High

768065

NSA2
Ribosome biogenesis protein NSA2

1

1

High-throughput

0.479

High

810945

MTR4
ATP-dependent RNA helicase DOB1

1

2

Small-scale

0.479

High

864151

HST2
NAD-dependent protein deacetylase HST2

1

13

High-throughput

0.479

High

865629

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

20

High-throughput

0.479

High

959892

NUM1
Nuclear migration protein NUM1

1

19

High-throughput

0.479

High

971917

NU116
Nucleoporin NUP116/NSP116

1

1

Small-scale

0.479

High

972025

ULP1
Ubiquitin-like-specific protease 1

1

1

High-throughput

0.479

High

974320

ESP1
Separin

1

1

High-throughput

0.479

High

978037

RUVB1
RuvB-like protein 1

1

4

High-throughput

0.479

High

980176

ERB1
Ribosome biogenesis protein ERB1

1

18

High-throughput

0.479

High

986271

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

992629

RLP24
Ribosome biogenesis protein RLP24

1

1

High-throughput

0.479

High

1014859

RIO1
Serine/threonine-protein kinase RIO1

1

3

High-throughput

0.479

High

1014860

SIZ2
E3 SUMO-protein ligase SIZ2

1

6

High-throughput

0.479

High

1014863

RUVB2
RuvB-like protein 2

1

4

High-throughput

0.479

High

756316

AP18A
Clathrin coat assembly protein AP180A

1

5

High-throughput

0.470

High

797731

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

1

20

High-throughput

0.470

High

702729

TYE7
Transcription factor TYE7

1

0

High-throughput

0.460

High

987949

NDE1
Nuclear distribution protein nudE homolog 1

1

0

High-throughput

0.460

High

988460

HDA2
HDA1 complex subunit 2

1

0

High-throughput

0.460

High

407379

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

408171

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

499107

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.458

High

608490

SAN1
Protein SAN1

1

0

Small-scale

0.458

High

688477

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

700752

ATO2
Ammonia transport outward protein 2

1

0

High-throughput

0.458

High

733684

LAS1
Protein LAS1

1

0

Small-scale

0.458

High

733968

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.458

High

746279

YBC8
UPF0642 protein YBL028C

1

0

High-throughput

0.458

High

748738

ENP1
Essential nuclear protein 1

1

0

High-throughput

0.458

High

764269

NOC2
Nucleolar complex protein 2

1

0

Small-scale

0.458

High

774590

BMT5
25S rRNA

1

0

High-throughput

0.458

High

778884

NOP2
25S rRNA

1

0

High-throughput

0.458

High

810601

ALB1
Ribosome biogenesis protein ALB1

1

0

High-throughput

0.458

High

864549

TR112
Multifunctional methyltransferase subunit TRM112

1

0

Small-scale

0.458

High

978446

RRP17
Ribosomal RNA-processing protein 17

1

0

High-throughput

0.458

High

987683

NOC4
Nucleolar complex protein 4

1

0

High-throughput

0.458

High

996378

RRS1
Regulator of ribosome biosynthesis

1

0

High-throughput

0.458

High

997031

NIP7
60S ribosome subunit biogenesis protein NIP7

1

0

High-throughput

0.458

High

1014857

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

1014862

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1014864

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.458

High

368484

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.445

High

427308

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

1

High-throughput

0.445

High

513077

SSB1
Ribosome-associated molecular chaperone SSB1

1

10

High-throughput

0.445

High

695734

HSP7F
Heat shock protein homolog SSE1

1

14

High-throughput

0.445

High

753195

DBP8
ATP-dependent RNA helicase DBP8

1

5

High-throughput

0.445

High

837195

PHB2
Prohibitin-2

1

7

High-throughput

0.445

High

860310

TAM41
Phosphatidate cytidylyltransferase, mitochondrial

1

1

High-throughput

0.445

High

759278

END3
Actin cytoskeleton-regulatory complex protein END3

1

2

High-throughput

0.439

High

988721

IMH1
Golgin IMH1

1

19

High-throughput

0.439

High

471303

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

480935

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.437

High

645154

RL16A
Large ribosomal subunit protein uL13A

1

1

High-throughput

0.437

High

700668

RSSA1
Small ribosomal subunit protein uS2A

1

3

High-throughput

0.437

High

730161

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.437

High

767636

GLE2
mRNA export factor GLE2

1

15

Small-scale

0.437

High

996339

RS10A
Small ribosomal subunit protein eS10A

1

7

High-throughput

0.437

High

561266

APA1
Protein APA1 [Includes: Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase 1

1

0

High-throughput

0.426

High

752061

SRP72
Signal recognition particle subunit SRP72

1

0

High-throughput

0.426

High

1014858

NSL1
Kinetochore-associated protein NSL1

1

0

High-throughput

0.426

High

764161

RV167
Reduced viability upon starvation protein 167

1

5

High-throughput

0.407

High

785263

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.279

Low

860080

ERG26
Sterol-4-alpha-carboxylate 3-dehydrogenase ERG26, decarboxylating

1

0

High-throughput

0.279

Low

977377

USA1
U1 SNP1-associating protein 1

1

0

High-throughput

0.279

Low

358299

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

405873

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

564392

RL8A
Large ribosomal subunit protein eL8A

1

0

High-throughput

0.249

Low

706542

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

762643

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

967811

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

991333

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

733720

GPT2
Glycerol-3-phosphate O-acyltransferase 2

1

0

High-throughput

0.232

Low

978521

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024