Protein: VTC2
Vacuolar transporter chaperone complex subunit 2 (Phosphate metabolism protein 1) (SPX-dependent polyphosphate polymerase VTC subunit 2) (Vacuolar membrane polyphosphate polymerase accessory subunit 2) (PolyP polymerase)

Gene: VTC2
Organism: Saccharomyces cerevisiae S288C
Interactions: 75
UniProt ID: P43585

Gene Ontology (top 5):
GO:0000329 - fungal-type vacuole membrane
GO:0000421 - autophagosome membrane
GO:0000822 - inositol hexakisphosphate binding
GO:0005516 - calmodulin binding
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

849959

VTC4
Vacuolar transporter chaperone complex subunit 4

3

15

Small-scale

0.840

High

817471

VTC1
Vacuolar transporter chaperone complex subunit 1

2

15

Small-scale

0.799

High

849957

VTC2
Vacuolar transporter chaperone complex subunit 2

1

15

High-throughput

0.618

High

849970

VTC3
Vacuolar transporter chaperone 3 complex subunit 3

1

15

High-throughput

0.618

High

808350

VTC5
Vacuole transporter chaperone complex subunit 5

2

4

Small-scale

0.584

High

449140

CALM
Calmodulin

1

2

Small-scale

0.561

High

849977

YO075
Uncharacterized ABC transporter ATP-binding protein/permease YOL075C

1

3

High-throughput

0.541

High

727124

HS104
Heat shock protein 104

2

4

High-throughput

0.521

High

849962

PDR10
ATP-dependent permease PDR10

1

3

High-throughput

0.494

High

849978

AUS1
ATP-dependent permease AUS1

1

3

High-throughput

0.494

High

524317

HSP71
Heat shock protein SSA1

1

11

High-throughput

0.479

High

526987

HSP72
Heat shock protein SSA2

1

11

High-throughput

0.479

High

545305

SSB1
Ribosome-associated molecular chaperone SSB1

1

14

High-throughput

0.479

High

547061

PPB
Repressible alkaline phosphatase

1

5

High-throughput

0.479

High

575730

BPT1
Bile pigment transporter 1

1

17

High-throughput

0.479

High

592328

VATB
V-type proton ATPase subunit B

1

3

High-throughput

0.479

High

603497

VATA
V-type proton ATPase catalytic subunit A

1

9

High-throughput

0.479

High

628268

ZRC1
Vacuolar zinc transporter ZRC1

1

9

High-throughput

0.479

High

645838

VATE
V-type proton ATPase subunit E

1

5

High-throughput

0.479

High

672684

BPH1
Beige protein homolog 1

1

2

High-throughput

0.479

High

673300

ADP1
Probable ATP-dependent permease

1

7

High-throughput

0.479

High

679809

CDC48
Cell division control protein 48

1

4

High-throughput

0.479

High

693195

PHO91
Low-affinity phosphate transporter PHO91

1

10

High-throughput

0.479

High

735733

VA0D
V-type proton ATPase subunit d

1

5

High-throughput

0.479

High

736194

YBT1
ATP-dependent bile acid permease

1

17

High-throughput

0.479

High

740073

VPP1
V-type proton ATPase subunit a, vacuolar isoform

1

7

High-throughput

0.479

High

743467

SEC17
Alpha-soluble NSF attachment protein

1

2

High-throughput

0.479

High

743695

VATD
V-type proton ATPase subunit D

1

5

High-throughput

0.479

High

745214

COT1
Vacuolar zinc transporter COT1

1

9

High-throughput

0.479

High

746011

VATL2
V-type proton ATPase subunit c'

1

5

High-throughput

0.479

High

780769

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

4

High-throughput

0.479

High

796496

PFF1
Vacuolar membrane protease

1

5

High-throughput

0.479

High

811622

YCFI
Metal resistance protein YCF1

1

17

High-throughput

0.479

High

811664

VATF
V-type proton ATPase subunit F

1

4

High-throughput

0.479

High

812416

LAA1
AP-1 accessory protein LAA1

1

3

High-throughput

0.479

High

815865

KC13
Casein kinase I homolog 3

1

4

High-throughput

0.479

High

815974

VAC8
Vacuolar protein 8

1

4

High-throughput

0.479

High

825941

SYG1
Protein SYG1

1

10

High-throughput

0.479

High

843155

VNX1
Low affinity vacuolar monovalent cation/H(+) antiporter

1

10

High-throughput

0.479

High

849958

RMD8
Sporulation protein RMD8

1

11

High-throughput

0.479

High

849960

VATG
V-type proton ATPase subunit G

1

6

High-throughput

0.479

High

849963

VOA1
V0 assembly protein 1

1

3

High-throughput

0.479

High

849964

VSB1
Vacuolar basic amino acid transporter VSB1

1

5

High-throughput

0.479

High

849968

NUM1
Nuclear migration protein NUM1

1

5

High-throughput

0.479

High

849972

RMD1
Sporulation protein RMD1

1

11

High-throughput

0.479

High

849975

CSC1
Calcium permeable stress-gated cation channel 1

1

2

High-throughput

0.479

High

849980

SMF3
Iron transporter SMF3

1

3

High-throughput

0.479

High

849981

NPC1
NPC intracellular sterol transporter 1-related protein 1

1

4

High-throughput

0.479

High

849982

NYV1
Vacuolar v-SNARE NYV1

1

6

High-throughput

0.479

High

849983

YVC1
Calcium channel YVC1

1

5

High-throughput

0.479

High

849984

VCX1
Vacuolar calcium ion transporter

1

10

High-throughput

0.479

High

849965

LSB1
LAS seventeen-binding protein 1

1

4

High-throughput

0.457

High

849974

PIN3
[PSI+] inducibility protein 3

1

4

High-throughput

0.457

High

849969

UBC7
Ubiquitin-conjugating enzyme E2 7

1

2

High-throughput

0.457

High

365087

KPYK1
Pyruvate kinase 1

1

3

High-throughput

0.437

High

579602

HSC82
ATP-dependent molecular chaperone HSC82

1

9

High-throughput

0.437

High

647149

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

3

High-throughput

0.437

High

704787

MSP1
Outer mitochondrial transmembrane helix translocase

1

2

Small-scale

0.437

High

707427

TF2B
Transcription initiation factor IIB

1

7

High-throughput

0.437

High

739670

SPT16
FACT complex subunit SPT16

1

1

High-throughput

0.437

High

780500

MCR1
NADH-cytochrome b5 reductase 2

1

1

Small-scale

0.437

High

795054

NU170
Nucleoporin NUP170

1

6

High-throughput

0.437

High

812064

DHH1
ATP-dependent RNA helicase DHH1

1

2

High-throughput

0.437

High

824902

TM108
Protein TMA108

1

2

High-throughput

0.437

High

849961

TOM22
Mitochondrial import receptor subunit TOM22

1

2

High-throughput

0.437

High

849973

SCC2
Sister chromatid cohesion protein 2

1

2

High-throughput

0.437

High

849979

AP3D
AP-3 complex subunit delta

1

2

High-throughput

0.437

High

392921

HSP82
ATP-dependent molecular chaperone HSP82

1

9

High-throughput

0.407

High

819065

SSB2
Ribosome-associated molecular chaperone SSB2

1

14

High-throughput

0.407

High

849976

COS7
Protein COS7

1

0

High-throughput

0.282

High

403551

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.249

Low

849967

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.249

Low

849971

ESP1
Separin

1

0

High-throughput

0.249

Low

849966

CWC25
Pre-mRNA-splicing factor CWC25

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025