Protein: OTU1
Ubiquitin thioesterase OTU1 (EC 3.4.19.12) (OTU domain-containing protein 1)

Gene: OTU1
Organism: Saccharomyces cerevisiae S288C
Interactions: 72
UniProt ID: P43558

Gene Ontology (top 5):
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006355 - regulation of DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

477333

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

3

14

Small-scale

0.862

High

636659

CDC48
Cell division control protein 48

10

2

Small-scale

0.755

High

491583

HSP71
Heat shock protein SSA1

3

3

High-throughput

0.650

High

710559

UBX1
UBX domain-containing protein 1

2

1

Small-scale

0.632

High

797102

UFD2
E4 ubiquitin-protein ligase UFD2

2

1

Small-scale

0.632

High

511733

SSB1
Ribosome-associated molecular chaperone SSB1

3

3

High-throughput

0.624

High

408394

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

5

High-throughput

0.618

High

477630

RL40A
Ubiquitin-ribosomal protein eL40A fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40A

1

3

High-throughput

0.618

High

797098

OTU1
Ubiquitin thioesterase OTU1

1

7

High-throughput

0.618

High

731507

DOA1
Protein DOA1

1

2

Small-scale

0.573

High

494255

HSP72
Heat shock protein SSA2

2

3

High-throughput

0.571

High

768729

SSB2
Ribosome-associated molecular chaperone SSB2

2

3

High-throughput

0.571

High

797106

HRD1
ERAD-associated E3 ubiquitin-protein ligase HRD1

1

3

Small-scale

0.569

High

707237

NPL4
Nuclear protein localization protein 4

1

1

Small-scale

0.561

High

797100

UFD1
Ubiquitin fusion degradation protein 1

1

1

Small-scale

0.561

High

356543

H4
Histone H4

2

0

High-throughput

0.547

High

341097

CBPY
Carboxypeptidase Y

1

0

Small-scale

0.480

High

771528

SECU
Securin

1

0

Small-scale

0.480

High

389942

VDAC1
Mitochondrial outer membrane protein porin 1

1

1

High-throughput

0.479

High

405686

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.479

High

406016

RL33A
Large ribosomal subunit protein eL33A

1

2

High-throughput

0.479

High

406361

RL15A
Large ribosomal subunit protein eL15A

1

1

High-throughput

0.479

High

407544

RS9B
Small ribosomal subunit protein uS4B

1

2

High-throughput

0.479

High

426455

SYSC
Serine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

472254

RL31A
Large ribosomal subunit protein eL31A

1

2

High-throughput

0.479

High

479768

RS4A
Small ribosomal subunit protein eS4A

1

1

High-throughput

0.479

High

480735

RS8A
Small ribosomal subunit protein eS8A

1

2

High-throughput

0.479

High

481173

RL1A
Large ribosomal subunit protein uL1A

1

2

High-throughput

0.479

High

481525

RS11B
Small ribosomal subunit protein uS17B

1

1

High-throughput

0.479

High

498542

METK1
S-adenosylmethionine synthase 1

1

1

High-throughput

0.479

High

543941

HSC82
ATP-dependent molecular chaperone HSC82

1

2

High-throughput

0.479

High

562251

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

1

High-throughput

0.479

High

629994

BPH1
Beige protein homolog 1

1

2

High-throughput

0.479

High

631944

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

645060

RL16A
Large ribosomal subunit protein uL13A

1

2

High-throughput

0.479

High

645231

RL16B
Large ribosomal subunit protein uL13B

1

2

High-throughput

0.479

High

662545

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

687413

EF2
Elongation factor 2

1

1

High-throughput

0.479

High

700479

RSSA1
Small ribosomal subunit protein uS2A

1

3

High-throughput

0.479

High

712946

BMH2
Protein BMH2

1

1

High-throughput

0.479

High

713238

TSA1
Peroxiredoxin TSA1

1

3

High-throughput

0.479

High

716543

SPT23
Protein SPT23

1

3

Small-scale

0.479

High

780482

RL33B
Large ribosomal subunit protein eL33B

1

2

High-throughput

0.479

High

797099

RL17B
Large ribosomal subunit protein uL22B

1

2

High-throughput

0.479

High

797103

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.479

High

797105

TSA2
Peroxiredoxin TSA2

1

3

High-throughput

0.479

High

410813

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

0

High-throughput

0.458

High

421657

FAS1
Fatty acid synthase subunit beta

1

0

High-throughput

0.458

High

425029

DHE4
NADP-specific glutamate dehydrogenase 1

1

0

High-throughput

0.458

High

426391

PMM
Phosphomannomutase

1

0

High-throughput

0.458

High

535030

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

613819

TKT1
Transketolase 1

1

0

High-throughput

0.458

High

678223

DHOM
Homoserine dehydrogenase

1

0

High-throughput

0.458

High

727652

TCTP
Translationally-controlled tumor protein homolog

1

0

High-throughput

0.458

High

752845

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

765550

SAHH
Adenosylhomocysteinase

1

0

High-throughput

0.458

High

797104

COFI
Cofilin

1

0

High-throughput

0.458

High

797107

HOSM
Homocitrate synthase, mitochondrial

1

0

High-throughput

0.458

High

797108

NOP56
Nucleolar protein 56

1

0

High-throughput

0.458

High

797109

RL13A
Large ribosomal subunit protein eL13A

1

0

High-throughput

0.458

High

797101

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

1

High-throughput

0.457

High

694930

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.445

High

549423

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

2

High-throughput

0.437

High

575977

ADT2
ADP,ATP carrier protein 2

1

1

High-throughput

0.437

High

619599

MPCP
Mitochondrial phosphate carrier protein

1

2

High-throughput

0.437

High

368169

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

447798

CDC6
Cell division control protein 6

1

0

High-throughput

0.426

High

785073

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.426

High

704042

PDR5
Pleiotropic ABC efflux transporter of multiple drugs

1

0

Small-scale

0.251

Low

561006

EF3A
Elongation factor 3A

1

0

High-throughput

0.249

Low

690680

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024