Protein: LAS17
Proline-rich protein LAS17

Gene: LAS17
Organism: Saccharomyces cerevisiae S288C
Interactions: 163
UniProt ID: Q12446

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0005737 - cytoplasm
GO:0007015 - actin filament organization
GO:0030041 - actin filament polymerization
GO:0030479 - actin cortical patch

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

741563

VRP1
Verprolin

15

10

Small-scale

0.987

High

887724

ACT
Actin

11

13

Small-scale

0.978

High

689396

ARP2
Actin-related protein 2

11

15

Small-scale

0.977

High

811973

ARP3
Actin-related protein 3

7

16

Small-scale

0.957

High

1015602

LAS17
Proline-rich protein LAS17

4

11

Small-scale

0.887

High

764174

RV167
Reduced viability upon starvation protein 167

17

20

Small-scale

0.765

High

698028

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

15

9

Small-scale

0.764

High

755687

BZZ1
Protein BZZ1

9

20

Small-scale

0.760

High

797883

LSB3
LAS seventeen-binding protein 3

8

20

Small-scale

0.758

High

698143

YSC84
Protein YSC84

8

20

Small-scale

0.757

High

979583

MYO5
Myosin-5

9

8

Small-scale

0.757

High

748566

ARPC1
Actin-related protein 2/3 complex subunit 1

7

10

Small-scale

0.744

High

987382

PIN3
[PSI+] inducibility protein 3

6

20

Small-scale

0.738

High

730603

MYO3
Myosin-3

6

8

Small-scale

0.738

High

861166

LSB1
LAS seventeen-binding protein 1

5

20

Small-scale

0.725

High

811160

BBC1
Myosin tail region-interacting protein MTI1

5

7

Small-scale

0.718

High

767932

SHO1
High osmolarity signaling protein SHO1

4

1

Small-scale

0.703

High

704812

SLA2
Protein SLA2

4

6

High-throughput

0.700

High

759285

END3
Actin cytoskeleton-regulatory complex protein END3

4

10

High-throughput

0.700

High

864473

ARPC2
Actin-related protein 2/3 complex subunit 2

4

5

Small-scale

0.690

High

985319

ARPC3
Actin-related protein 2/3 complex subunit 3

4

4

Small-scale

0.690

High

604492

CLH
Clathrin heavy chain

3

2

Small-scale

0.662

High

983058

CYK2
Cytokinesis protein 2

3

20

Small-scale

0.660

High

629680

RV161
Reduced viability upon starvation protein 161

3

10

Small-scale

0.648

High

775041

ARPC5
Actin-related protein 2/3 complex subunit 5

3

2

Small-scale

0.636

High

630580

LSB5
LAS seventeen-binding protein 5

3

0

Small-scale

0.625

High

792684

LSB6
Phosphatidylinositol 4-kinase LSB6

3

0

Small-scale

0.615

High

635330

SYP1
Suppressor of yeast profilin deletion

2

7

Small-scale

0.614

High

703314

ARPC4
Actin-related protein 2/3 complex subunit 4

2

3

Small-scale

0.614

High

765440

RSP5
E3 ubiquitin-protein ligase RSP5

2

9

Small-scale

0.605

High

695855

HSP7F
Heat shock protein homolog SSE1

2

8

High-throughput

0.601

High

774633

PRK1
Actin-regulating kinase PRK1

2

3

Small-scale

0.595

High

556390

VATB
V-type proton ATPase subunit B

2

5

Small-scale

0.594

High

528342

CAPZB
F-actin-capping protein subunit beta

2

3

Small-scale

0.584

High

696482

FIMB
Fimbrin

2

1

Small-scale

0.584

High

860652

PIL1
Sphingolipid long chain base-responsive protein PIL1

2

1

Small-scale

0.584

High

478626

HSP77
Import motor subunit, mitochondrial

2

4

High-throughput

0.571

High

1015467

HSP42
Heat shock protein 42

2

0

Small-scale

0.569

High

429257

SEC4
Ras-related protein SEC4

1

5

Small-scale

0.543

High

450244

HSP73
Heat shock protein SSA3

1

5

Small-scale

0.536

High

691287

MYO4
Myosin-4

1

3

High-throughput

0.536

High

715630

SQT1
Ribosome assembly protein SQT1

1

3

High-throughput

0.536

High

753988

RPN1
26S proteasome regulatory subunit RPN1

1

4

High-throughput

0.536

High

666296

BEM1
Bud emergence protein 1

1

20

Small-scale

0.515

High

748826

RGD1
RHO GTPase-activating protein RGD1

1

4

High-throughput

0.508

High

1015605

ENT1
Epsin-1

1

2

High-throughput

0.508

High

606185

RAD53
Serine/threonine-protein kinase RAD53

1

4

High-throughput

0.501

High

615102

KC12
Casein kinase I homolog 2

1

3

High-throughput

0.501

High

752253

KSP1
Serine/threonine-protein kinase KSP1

1

2

High-throughput

0.501

High

424773

PYR1
Multifunctional protein URA2

1

2

High-throughput

0.500

High

454511

TBA1
Tubulin alpha-1 chain

1

4

High-throughput

0.500

High

454674

TBA3
Tubulin alpha-3 chain

1

4

High-throughput

0.500

High

633712

MAS5
Mitochondrial protein import protein MAS5

1

3

High-throughput

0.500

High

753657

HSE1
Class E vacuolar protein-sorting machinery protein HSE1

1

17

High-throughput

0.494

High

974373

COFI
Cofilin

1

0

Small-scale

0.493

High

526120

GAL2
Galactose transporter

1

2

High-throughput

0.489

High

572070

CLC1
Clathrin light chain

1

2

High-throughput

0.489

High

575902

ADT3
ADP,ATP carrier protein 3

1

2

High-throughput

0.489

High

628738

PHO84
Inorganic phosphate transporter PHO84

1

3

High-throughput

0.489

High

687124

VPS10
Vacuolar protein sorting/targeting protein VPS10

1

1

High-throughput

0.489

High

759020

HXT6
High-affinity hexose transporter HXT6

1

2

High-throughput

0.489

High

759045

HXT7
High-affinity hexose transporter HXT7

1

2

High-throughput

0.489

High

864777

YN94
Uncharacterized membrane glycoprotein YNR065C

1

1

High-throughput

0.489

High

978428

YHM2
Citrate/oxoglutarate carrier protein

1

2

High-throughput

0.489

High

361090

TBB
Tubulin beta chain

1

0

High-throughput

0.479

High

381505

GAL1
Galactokinase

1

0

High-throughput

0.479

High

389344

HXKA
Hexokinase-1

1

0

High-throughput

0.479

High

699383

UGPA1
UTP--glucose-1-phosphate uridylyltransferase

1

0

High-throughput

0.479

High

367118

HSP82
ATP-dependent molecular chaperone HSP82

1

10

Small-scale

0.479

High

420359

CALM
Calmodulin

1

9

Small-scale

0.479

High

544632

HSC82
ATP-dependent molecular chaperone HSC82

1

10

Small-scale

0.479

High

551400

ABP1
Actin-binding protein

1

20

Small-scale

0.479

High

613092

SPA2
Protein SPA2

1

8

Small-scale

0.479

High

643221

PPZ1
Serine/threonine-protein phosphatase PP-Z1

1

3

Small-scale

0.479

High

659130

CAPZA
F-actin-capping protein subunit alpha

1

2

Small-scale

0.479

High

691675

NUP2
Nucleoporin NUP2

1

4

Small-scale

0.479

High

692255

PAN1
Actin cytoskeleton-regulatory complex protein PAN1

1

13

Small-scale

0.479

High

694317

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

1

High-throughput

0.479

High

711016

HSL1
Probable serine/threonine-protein kinase HSL1

1

1

Small-scale

0.479

High

715254

TOR1
Serine/threonine-protein kinase TOR1

1

7

Small-scale

0.479

High

715871

MDJ1
DnaJ homolog 1, mitochondrial

1

3

Small-scale

0.479

High

716057

GCS1
ADP-ribosylation factor GTPase-activating protein GCS1

1

7

Small-scale

0.479

High

728865

KES1
Oxysterol-binding protein homolog 4

1

4

Small-scale

0.479

High

747571

AIM3
Altered inheritance of mitochondria protein 3

1

12

Small-scale

0.479

High

756611

KOG1
Target of rapamycin complex 1 subunit KOG1

1

5

Small-scale

0.479

High

765599

SAP1
Protein SAP1

1

2

Small-scale

0.479

High

771779

TBP6
Probable 26S proteasome subunit YTA6

1

2

Small-scale

0.479

High

773910

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

3

Small-scale

0.479

High

774538

SLM1
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1

1

1

Small-scale

0.479

High

797775

YFI6
Uncharacterized protein YFR016C

1

6

Small-scale

0.479

High

860517

TWF1
Twinfilin-1

1

1

Small-scale

0.479

High

861137

YG3A
Uncharacterized protein YGR130C

1

10

Small-scale

0.479

High

861307

PBP1
PAB1-binding protein 1

1

1

Small-scale

0.479

High

979229

SEG1
Eisosome protein SEG1

1

1

Small-scale

0.479

High

981017

AVO2
Target of rapamycin complex 2 subunit AVO2

1

7

Small-scale

0.479

High

983031

EIS1
Eisosome protein 1

1

4

Small-scale

0.479

High

984789

ENT2
Epsin-2

1

7

High-throughput

0.479

High

987368

CORO
Coronin-like protein

1

6

Small-scale

0.479

High

996548

SCP1
Transgelin

1

4

Small-scale

0.479

High

1015355

LSP1
Sphingolipid long chain base-responsive protein LSP1

1

1

Small-scale

0.479

High

744181

ATR
Serine/threonine-protein kinase MEC1

1

7

High-throughput

0.470

High

756241

LIN1
Protein LIN1

1

1

High-throughput

0.464

High

1015606

VPS5
Vacuolar protein sorting-associated protein 5

1

7

High-throughput

0.464

High

611760

TRX2
Thioredoxin-2

1

0

Small-scale

0.458

High

682299

ACBP
Acyl-CoA-binding protein

1

0

Small-scale

0.458

High

701147

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

741356

STT4
Phosphatidylinositol 4-kinase STT4

1

0

Small-scale

0.458

High

747609

OPY1
Protein OPY1

1

0

Small-scale

0.458

High

747630

SHE3
SWI5-dependent HO expression protein 3

1

0

Small-scale

0.458

High

809643

YPP1
Cargo-transport protein YPP1

1

0

Small-scale

0.458

High

810810

BIT61
Target of rapamycin complex 2 subunit BIT61

1

0

Small-scale

0.458

High

866349

APP1
Phosphatidate phosphatase APP1

1

0

Small-scale

0.458

High

988058

BSP1
Protein BSP1

1

0

Small-scale

0.458

High

994481

AVO1
Target of rapamycin complex 2 subunit AVO1

1

0

Small-scale

0.458

High

995502

CUE5
Ubiquitin-binding protein CUE5

1

0

Small-scale

0.458

High

996154

AB140
tRNA(Thr)

1

0

Small-scale

0.458

High

688850

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

3

High-throughput

0.457

High

342148

ATPB
ATP synthase subunit beta, mitochondrial

1

5

High-throughput

0.457

High

423938

ATPA
ATP synthase subunit alpha, mitochondrial

1

5

High-throughput

0.457

High

520887

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

3

High-throughput

0.457

High

576030

ADT2
ADP,ATP carrier protein 2

1

2

High-throughput

0.457

High

619649

MPCP
Mitochondrial phosphate carrier protein

1

1

High-throughput

0.457

High

693379

RPN2
26S proteasome regulatory subunit RPN2

1

2

High-throughput

0.457

High

1015604

RUVB2
RuvB-like protein 2

1

2

High-throughput

0.457

High

492908

HSP71
Heat shock protein SSA1

1

5

High-throughput

0.445

High

513288

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

541935

NSP1
Nucleoporin NSP1

1

4

Small-scale

0.437

High

663730

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

696543

TOR2
Serine/threonine-protein kinase TOR2

1

7

Small-scale

0.437

High

711156

SEG2
Eisosome protein SEG2

1

1

Small-scale

0.437

High

758892

MSS4
Phosphatidylinositol 4-phosphate 5-kinase MSS4

1

3

Small-scale

0.437

High

761354

CAJ1
Protein CAJ1

1

4

Small-scale

0.437

High

817603

SEC16
COPII coat assembly protein SEC16

1

1

Small-scale

0.437

High

859595

MLC1
Myosin light chain 1

1

6

Small-scale

0.437

High

866715

SLM2
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM2

1

1

Small-scale

0.437

High

1015153

YP150
Putative serine/threonine-protein kinase YPL150W

1

2

Small-scale

0.437

High

1015603

OSH2
Oxysterol-binding protein homolog 2

1

3

Small-scale

0.437

High

756033

NSG1
Protein NSG1

2

0

High-throughput

0.307

High

1015405

RBD2
Rhomboid-type serine protease 2

2

0

High-throughput

0.307

High

691165

KRE6
Beta-glucan synthesis-associated protein KRE6

1

0

Small-scale

0.305

High

946222

PEX13
Peroxisomal membrane protein PEX13

1

0

High-throughput

0.296

High

689029

VA0D
V-type proton ATPase subunit d

1

0

High-throughput

0.279

Low

691510

RPN12
26S proteasome regulatory subunit RPN12

1

0

High-throughput

0.279

Low

588273

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.261

Low

968101

PRS8
26S proteasome regulatory subunit 8 homolog

1

0

High-throughput

0.261

Low

526633

PCY1
Choline-phosphate cytidylyltransferase

1

0

Small-scale

0.249

Low

675282

LCF1
Long-chain-fatty-acid--CoA ligase 1

1

0

Small-scale

0.249

Low

731026

MAOM
NAD-dependent malic enzyme, mitochondrial

1

0

Small-scale

0.249

Low

742746

PUR92
Bifunctional purine biosynthesis protein ADE17 [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase

1

0

Small-scale

0.249

Low

755968

NDT80
Meiosis-specific transcription factor NDT80

1

0

Small-scale

0.249

Low

767564

TSC11
Target of rapamycin complex 2 subunit TSC11

1

0

Small-scale

0.249

Low

810687

TAX4
Protein TAX4

1

0

Small-scale

0.249

Low

861505

YG5L
Uncharacterized protein YGR266W

1

0

Small-scale

0.249

Low

977070

EFR3
Protein EFR3

1

0

Small-scale

0.249

Low

977517

PML39
Pre-mRNA leakage protein 39

1

0

High-throughput

0.249

Low

982691

IVY1
Protein IVY1

1

0

Small-scale

0.249

Low

984819

MSC3
Meiotic sister-chromatid recombination protein 3

1

0

Small-scale

0.249

Low

984904

YL278
Uncharacterized transcriptional regulatory protein YLR278C

1

0

Small-scale

0.249

Low

992466

VPS13
Intermembrane lipid transfer protein VPS13

1

0

Small-scale

0.249

Low

996610

TCO89
Target of rapamycin complex 1 subunit TCO89

1

0

Small-scale

0.249

Low

1015116

PER33
Pore and endoplasmic reticulum protein of 33 kDa

1

0

High-throughput

0.249

Low

536715

SNA3
Protein SNA3

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024