Protein: ESF1
Pre-rRNA-processing protein ESF1 (18S rRNA factor 1)

Gene: ESF1
Organism: Saccharomyces cerevisiae S288C
Interactions: 178
UniProt ID: Q06344

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0006364 - rRNA processing
GO:0030490 - maturation of SSU-rRNA

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

864736

ESF2
Pre-rRNA-processing protein ESF2

6

1

Small-scale

0.736

High

593707

DBP4
ATP-dependent RNA helicase HCA4

4

3

High-throughput

0.705

High

635650

PWP2
Periodic tryptophan protein 2

3

1

High-throughput

0.662

High

987096

UTP4
U3 small nucleolar RNA-associated protein 4

3

1

High-throughput

0.654

High

792590

UTP10
U3 small nucleolar RNA-associated protein 10

4

0

High-throughput

0.653

High

860746

UTP22
U3 small nucleolar RNA-associated protein 22

3

0

Small-scale

0.643

High

816910

NOL10
Ribosome biogenesis protein ENP2

3

0

High-throughput

0.634

High

987095

BFR2
Protein BFR2

3

0

High-throughput

0.634

High

492513

HSP71
Heat shock protein SSA1

3

1

High-throughput

0.633

High

550127

CSK21
Casein kinase II subunit alpha

2

2

High-throughput

0.633

High

753051

RRP3
ATP-dependent rRNA helicase RRP3

2

3

High-throughput

0.628

High

987107

YRA1
RNA annealing protein YRA1

2

1

High-throughput

0.621

High

866059

NAT10
RNA cytidine acetyltransferase

2

1

High-throughput

0.614

High

634780

KRR1
KRR1 small subunit processome component

3

0

Small-scale

0.613

High

748712

ENP1
Essential nuclear protein 1

3

0

High-throughput

0.613

High

768118

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

2

1

High-throughput

0.611

High

987115

NOP58
Nucleolar protein 58

2

2

High-throughput

0.611

High

549505

FBRL
rRNA 2'-O-methyltransferase fibrillarin

2

1

Small-scale

0.601

High

655901

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

2

1

High-throughput

0.601

High

772681

UTP18
U3 small nucleolar RNA-associated protein 18

2

0

High-throughput

0.588

High

970472

UTP6
U3 small nucleolar RNA-associated protein 6

2

0

High-throughput

0.588

High

987092

ESF1
Pre-rRNA-processing protein ESF1

2

0

High-throughput

0.588

High

987106

SAS10
Something about silencing protein 10

2

0

High-throughput

0.588

High

756792

UTP9
U3 small nucleolar RNA-associated protein 9

2

0

High-throughput

0.585

High

982878

RRP5
rRNA biogenesis protein RRP5

2

0

High-throughput

0.585

High

985814

UTP21
U3 small nucleolar RNA-associated protein 21

2

2

Small-scale

0.584

High

704428

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

2

0

High-throughput

0.576

High

973677

UTP17
NET1-associated nuclear protein 1

2

3

High-throughput

0.571

High

632102

RS2
Small ribosomal subunit protein uS5

2

0

Small-scale

0.559

High

979720

UTP14
U3 small nucleolar RNA-associated protein 14

2

0

High-throughput

0.559

High

987094

NOC4
Nucleolar complex protein 4

2

0

High-throughput

0.559

High

730733

DHR2
Probable ATP-dependent RNA helicase DHR2

1

1

High-throughput

0.541

High

976864

HAS1
ATP-dependent RNA helicase HAS1

1

4

High-throughput

0.541

High

355654

H2B1
Histone H2B.1

1

2

High-throughput

0.536

High

548448

MS116
ATP-dependent RNA helicase MSS116, mitochondrial

1

4

High-throughput

0.536

High

584802

CSK22
Casein kinase II subunit alpha'

1

2

High-throughput

0.536

High

798389

CSK2B
Casein kinase II subunit beta

1

1

High-throughput

0.536

High

480895

RS8A
Small ribosomal subunit protein eS8A

2

1

High-throughput

0.533

High

705682

HSP78
Heat shock protein 78, mitochondrial

2

1

High-throughput

0.521

High

986071

SGD1
Suppressor of glycerol defect protein 1

1

0

High-throughput

0.518

High

633751

PUT3
Proline utilization trans-activator

1

1

High-throughput

0.515

High

424919

IF4E
Eukaryotic translation initiation factor 4E

1

0

High-throughput

0.513

High

499084

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.513

High

676390

XPO1
Exportin-1

1

0

High-throughput

0.513

High

704912

LHP1
La protein homolog

1

0

High-throughput

0.513

High

733942

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.513

High

987098

NOP12
Nucleolar protein 12

1

0

High-throughput

0.513

High

485590

SSBP1
Single-stranded nucleic acid-binding protein

1

1

High-throughput

0.500

High

761604

CAT8
Regulatory protein CAT8

1

0

High-throughput

0.493

High

987102

RRS1
Regulator of ribosome biosynthesis

1

0

High-throughput

0.493

High

987105

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.493

High

987110

GIN4
Serine/threonine-protein kinase GIN4

1

0

High-throughput

0.493

High

376936

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.479

High

605160

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.479

High

479824

RS4A
Small ribosomal subunit protein eS4A

1

2

High-throughput

0.479

High

648438

NSR1
Nuclear localization sequence-binding protein

1

1

Small-scale

0.479

High

753182

DBP8
ATP-dependent RNA helicase DBP8

1

3

High-throughput

0.479

High

776521

RLP7
Ribosome biogenesis protein RLP7

1

1

Small-scale

0.479

High

978634

UTP5
U3 small nucleolar RNA-associated protein 5

1

1

High-throughput

0.479

High

985420

UTP13
U3 small nucleolar RNA-associated protein 13

1

2

High-throughput

0.479

High

985901

MRD1
Multiple RNA-binding domain-containing protein 1

1

2

High-throughput

0.479

High

987109

UTP12
U3 small nucleolar RNA-associated protein 12

1

2

High-throughput

0.479

High

383362

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

405843

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.458

High

407333

RS3
Small ribosomal subunit protein uS3

1

0

Small-scale

0.458

High

408136

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

408471

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.458

High

413719

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

419504

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

0

High-throughput

0.458

High

426163

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

535124

RL3
Large ribosomal subunit protein uL3

1

0

Small-scale

0.458

High

630264

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

630543

RRP7
Ribosomal RNA-processing protein 7

1

0

High-throughput

0.458

High

645664

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

650395

SPT5
Transcription elongation factor SPT5

1

0

High-throughput

0.458

High

663383

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

688440

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

707143

DCA13
Protein SOF1

1

0

High-throughput

0.458

High

711076

UTP11
U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.458

High

730127

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

733605

RL1D1
Ribosome biogenesis protein UTP30

1

0

High-throughput

0.458

High

743009

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.458

High

743693

HMT1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.458

High

758473

RRP8
25S rRNA

1

0

High-throughput

0.458

High

767425

UTP7
U3 small nucleolar RNA-associated protein 7

1

0

High-throughput

0.458

High

774283

RRT14
Regulator of rDNA transcription protein 14

1

0

High-throughput

0.458

High

774753

UTP25
U3 small nucleolar RNA-associated protein 25

1

0

High-throughput

0.458

High

775392

FAF1
Protein FAF1

1

0

High-throughput

0.458

High

775868

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

799861

ROK1
ATP-dependent RNA helicase ROK1

1

0

High-throughput

0.458

High

811356

NOP9
Nucleolar protein 9

1

0

Small-scale

0.458

High

811563

MPP10
U3 small nucleolar RNA-associated protein MPP10

1

0

High-throughput

0.458

High

861032

UTP8
U3 small nucleolar RNA-associated protein 8

1

0

High-throughput

0.458

High

866495

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

866620

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

0

High-throughput

0.458

High

967772

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

978299

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

979031

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.458

High

979244

UTP15
U3 small nucleolar RNA-associated protein 15

1

0

High-throughput

0.458

High

979411

BUD22
Bud site selection protein 22

1

0

High-throughput

0.458

High

979453

PUF6
Pumilio homology domain family member 6

1

0

Small-scale

0.458

High

983771

FCF1
rRNA-processing protein FCF1

1

0

High-throughput

0.458

High

984215

HRQ1
ATP-dependent helicase HRQ1

1

0

Small-scale

0.458

High

986243

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

986752

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

0

High-throughput

0.458

High

987093

RRP9
Ribosomal RNA-processing protein 9

1

0

High-throughput

0.458

High

987097

RCL1
RNA 3'-terminal phosphate cyclase-like protein

1

0

High-throughput

0.458

High

987100

SGO1
Shugoshin

1

0

High-throughput

0.458

High

987101

UTP16
U3 small nucleolar RNA-associated protein 16

1

0

High-throughput

0.458

High

987103

BMS1
Ribosome biogenesis protein BMS1

1

0

High-throughput

0.458

High

987104

FCF2
rRNA-processing protein FCF2

1

0

High-throughput

0.458

High

987114

RRP36
rRNA biogenesis protein RRP36

1

0

High-throughput

0.458

High

987116

EFG1P
rRNA-processing protein EFG1

1

0

High-throughput

0.458

High

987117

NOP14
Nucleolar complex protein 14

1

0

High-throughput

0.458

High

392210

H2A1
Histone H2A.1

1

2

High-throughput

0.445

High

392579

H2A2
Histone H2A.2

1

2

High-throughput

0.445

High

495022

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

512821

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

681011

HS104
Heat shock protein 104

1

1

High-throughput

0.445

High

695581

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

769540

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

902081

H3
Histone H3

1

2

High-throughput

0.445

High

987108

RL7B
Large ribosomal subunit protein uL30B

1

1

High-throughput

0.445

High

987113

NOP56
Nucleolar protein 56

1

2

High-throughput

0.445

High

472405

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

481556

RS11B
Small ribosomal subunit protein uS17B

1

2

High-throughput

0.437

High

700634

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.437

High

959878

NUM1
Nuclear migration protein NUM1

1

1

High-throughput

0.437

High

356740

H4
Histone H4

1

0

High-throughput

0.426

High

554748

HSP26
Heat shock protein 26

1

0

High-throughput

0.426

High

641070

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.426

High

728321

DEF1
RNA polymerase II degradation factor 1

1

0

High-throughput

0.426

High

766362

SNU13
13 kDa ribonucleoprotein-associated protein

1

0

High-throughput

0.426

High

987099

NOP8
60S ribosome subunit biogenesis protein NOP8

1

0

High-throughput

0.426

High

987111

BMT6
25S rRNA

1

0

High-throughput

0.426

High

399641

RLA0
Large ribosomal subunit protein uL10

2

0

Small-scale

0.318

High

762579

LAA1
AP-1 accessory protein LAA1

2

0

High-throughput

0.318

High

760693

TCPB
T-complex protein 1 subunit beta

2

0

High-throughput

0.307

High

544451

HSC82
ATP-dependent molecular chaperone HSC82

2

0

High-throughput

0.298

High

393620

PMA1
Plasma membrane ATPase 1

1

0

High-throughput

0.279

Low

706500

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.279

Low

837360

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

0

High-throughput

0.279

Low

864612

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.279

Low

516915

SIR4
Regulatory protein SIR4

1

0

High-throughput

0.269

Low

540164

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.269

Low

667829

SEC65
Signal recognition particle subunit SEC65

1

0

High-throughput

0.269

Low

764141

RV167
Reduced viability upon starvation protein 167

1

0

High-throughput

0.269

Low

987112

PAA1
Polyamine N-acetyltransferase 1

1

0

High-throughput

0.269

Low

389330

HXKA
Hexokinase-1

1

0

High-throughput

0.261

Low

636101

YCX7
Putative uncharacterized protein YCR087W

1

0

High-throughput

0.261

Low

977793

YD102
Uncharacterized protein YDR102C

1

0

High-throughput

0.261

Low

358269

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

405282

RL17A
Large ribosomal subunit protein uL22A

1

0

High-throughput

0.249

Low

450513

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

0

Small-scale

0.249

Low

482471

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

630034

BPH1
Beige protein homolog 1

1

0

High-throughput

0.249

Low

737220

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.249

Low

752681

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

784228

RL10
Large ribosomal subunit protein uL16

1

0

Small-scale

0.249

Low

860382

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

861337

CRH1
Probable glycosidase CRH1

1

0

High-throughput

0.249

Low

972294

RL21A
Large ribosomal subunit protein eL21A

1

0

High-throughput

0.249

Low

977474

BUL2
Ubiquitin ligase-binding protein BUL2

1

0

Small-scale

0.249

Low

977554

GIR2
Protein GIR2

1

0

High-throughput

0.249

Low

626009

SPTC1
Serine palmitoyltransferase 1

1

0

High-throughput

0.238

Low

368425

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.232

Low

421696

FAS1
Fatty acid synthase subunit beta

1

0

High-throughput

0.232

Low

424722

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.232

Low

478543

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.232

Low

556312

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.232

Low

561072

EF3A
Elongation factor 3A

1

0

High-throughput

0.232

Low

588231

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.232

Low

697493

ATC5
Phospholipid-transporting ATPase DNF1

1

0

High-throughput

0.232

Low

785225

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low

810165

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low

811471

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.232

Low

983344

NUP59
Nucleoporin ASM4

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024