Protein: MED10
Mediator of RNA polymerase II transcription subunit 10 (Mediator complex subunit 10) (Negative regulator of URS2 protein 2)

Gene: MED10, NUT2
Organism: Saccharomyces cerevisiae S288C
Interactions: 44
UniProt ID: Q06213

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0016592 - mediator complex
GO:0032968 - positive regulation of transcription elongation by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

986568

MED7
Mediator of RNA polymerase II transcription subunit 7

9

6

Small-scale

0.967

High

581381

MED14
Mediator of RNA polymerase II transcription subunit 14

8

3

Small-scale

0.966

High

814168

MED21
Mediator of RNA polymerase II transcription subunit 21

8

0

Small-scale

0.917

High

754286

MED6
Mediator of RNA polymerase II transcription subunit 6

3

4

Small-scale

0.843

High

626043

MED19
Mediator of RNA polymerase II transcription subunit 19

4

0

High-throughput

0.836

High

751475

MED31
Mediator of RNA polymerase II transcription subunit 31

5

1

Small-scale

0.717

High

693941

MED18
Mediator of RNA polymerase II transcription subunit 18

6

0

Small-scale

0.697

High

748116

MED8
Mediator of RNA polymerase II transcription subunit 8

4

1

Small-scale

0.696

High

693606

MED22
Mediator of RNA polymerase II transcription subunit 22

5

0

Small-scale

0.682

High

986574

MED4
Mediator of RNA polymerase II transcription subunit 4

5

0

Small-scale

0.676

High

693566

MED17
Mediator of RNA polymerase II transcription subunit 17

4

0

Small-scale

0.657

High

986570

MED2
Mediator of RNA polymerase II transcription subunit 2

4

0

High-throughput

0.654

High

704161

MED9
Mediator of RNA polymerase II transcription subunit 9

4

0

Small-scale

0.653

High

586339

MED15
Mediator of RNA polymerase II transcription subunit 15

3

0

Small-scale

0.625

High

859241

MED5
Mediator of RNA polymerase II transcription subunit 5

3

0

Small-scale

0.622

High

986573

MED1
Mediator of RNA polymerase II transcription subunit 1

3

0

Small-scale

0.622

High

760593

SSN3
Meiotic mRNA stability protein kinase SSN3

2

2

Small-scale

0.611

High

636000

SRB8
Mediator of RNA polymerase II transcription subunit 12

2

2

Small-scale

0.595

High

814153

SSN8
RNA polymerase II holoenzyme cyclin-like subunit

2

2

Small-scale

0.595

High

663368

TF2B
Transcription initiation factor IIB

2

0

Small-scale

0.581

High

686866

MED16
Mediator of RNA polymerase II transcription subunit 16

2

0

High-throughput

0.576

High

710276

MED20
Mediator of RNA polymerase II transcription subunit 20

2

0

High-throughput

0.576

High

772518

MED3
Mediator of RNA polymerase II transcription subunit 3

2

0

High-throughput

0.576

High

986576

MED11
Mediator of RNA polymerase II transcription subunit 11

2

0

High-throughput

0.576

High

758024

SSN2
Mediator of RNA polymerase II transcription subunit 13

2

0

Small-scale

0.569

High

715394

SPT7
Transcriptional activator SPT7

1

1

High-throughput

0.536

High

419966

SNF1
Carbon catabolite-derepressing protein kinase

1

0

Small-scale

0.518

High

548622

IDI1
Isopentenyl-diphosphate delta-isomerase

1

0

High-throughput

0.518

High

558264

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

Small-scale

0.501

High

636752

CDC48
Cell division control protein 48

1

0

High-throughput

0.493

High

710579

UBX1
UBX domain-containing protein 1

1

0

High-throughput

0.493

High

755867

LSM12
Protein LSM12

1

0

High-throughput

0.493

High

561911

TUP1
General transcriptional corepressor TUP1

1

2

Small-scale

0.481

High

986575

CMR1
DNA damage-binding protein CMR1

1

1

High-throughput

0.481

High

697661

TOA1
Transcription initiation factor IIA large subunit

1

0

Small-scale

0.480

High

810835

IKS1
Probable serine/threonine-protein kinase IKS1

1

0

High-throughput

0.480

High

728320

DEF1
RNA polymerase II degradation factor 1

1

1

High-throughput

0.479

High

715738

TAF14
Transcription initiation factor TFIID subunit 14

1

0

High-throughput

0.458

High

716509

SPT21
Protein SPT21

1

0

High-throughput

0.458

High

751087

RCK1
Serine/threonine-protein kinase RCK1

1

0

High-throughput

0.458

High

986569

TAF10
Transcription initiation factor TFIID subunit 10

1

0

High-throughput

0.458

High

986571

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

355651

H2B1
Histone H2B.1

1

1

High-throughput

0.445

High

986572

RIO1
Serine/threonine-protein kinase RIO1

1

1

High-throughput

0.445

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024