Protein: PEP5
E3 ubiquitin-protein ligase PEP5 (EC 2.3.2.27) (Carboxypeptidase Y-deficient protein 5) (Histone E3 ligase PEP5) (RING-type E3 ubiquitin transferase PEP5) (Vacuolar biogenesis protein END1) (Vacuolar morphogenesis protein 1) (Vacuolar protein sorting-associated protein 11) (Vacuolar protein-targeting protein 11)

Gene: PEP5
Organism: Saccharomyces cerevisiae S288C
Interactions: 49
UniProt ID: P12868

Gene Ontology (top 5):
GO:0000329 - fungal-type vacuole membrane
GO:0005768 - endosome
GO:0005829 - cytosol
GO:0006886 - intracellular protein transport
GO:0006895 - Golgi to endosome transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

522453

VPS41
Vacuolar protein sorting-associated protein 41

15

4

Small-scale

0.762

High

522469

VAM6
Vacuolar morphogenesis protein 6

13

10

Small-scale

0.761

High

522440

PEP3
Vacuolar membrane protein PEP3

9

10

Small-scale

0.760

High

522435

VPS33
Vacuolar protein sorting-associated protein 33

11

3

Small-scale

0.757

High

522454

VPS8
Vacuolar protein sorting-associated protein 8

9

1

Small-scale

0.752

High

522466

VPS16
Vacuolar protein sorting-associated protein 16

6

2

Small-scale

0.738

High

522445

VAM7
Vacuolar morphogenesis protein 7

6

1

Small-scale

0.730

High

522437

VPS3
Vacuolar protein sorting-associated protein 3

8

0

Small-scale

0.714

High

522447

YPT7
Ypt/Rab-type GTPase YPT7

4

3

Small-scale

0.692

High

522472

VAM3
Syntaxin VAM3

4

5

Small-scale

0.689

High

522433

PEP5
E3 ubiquitin-protein ligase PEP5

2

1

Small-scale

0.600

High

522443

PEP7
Vacuolar segregation protein PEP7

2

0

Small-scale

0.575

High

522434

UBC4
Ubiquitin-conjugating enzyme E2 4

1

1

Small-scale

0.561

High

522456

SSB2
Ribosome-associated molecular chaperone SSB2

2

1

High-throughput

0.552

High

522461

MON1
Vacuolar fusion protein MON1

1

2

Small-scale

0.508

High

522448

VPS21
Vacuolar protein sorting-associated protein 21

1

3

Small-scale

0.481

High

522449

YPT52
GTP-binding protein YPT52

1

3

Small-scale

0.481

High

522459

YPT11
GTP-binding protein YPT11

1

1

Small-scale

0.481

High

522451

CCZ1
Vacuolar fusion protein CCZ1

1

0

Small-scale

0.480

High

522455

KC13
Casein kinase I homolog 3

1

0

Small-scale

0.480

High

522470

AP3D
AP-3 complex subunit delta

1

0

Small-scale

0.480

High

522462

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.479

High

406725

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

425717

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

482037

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

522436

VPS34
Phosphatidylinositol 3-kinase VPS34

1

0

High-throughput

0.458

High

522438

BPH1
Beige protein homolog 1

1

0

High-throughput

0.458

High

522441

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

522444

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

522460

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

522464

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

522465

BECN1
Vacuolar protein sorting-associated protein 30

1

0

High-throughput

0.458

High

522467

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

522468

VTI1
t-SNARE VTI1

1

0

Small-scale

0.458

High

522471

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

510075

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

522439

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

493052

HSP72
Heat shock protein SSA2

1

0

High-throughput

0.426

High

522442

PP12
Serine/threonine-protein phosphatase PP1-2

1

0

High-throughput

0.426

High

356207

H4
Histone H4

1

0

Small-scale

0.292

High

474315

U5072
UPF0507 protein YML002W

1

0

Small-scale

0.251

Low

522446

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

522450

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

522457

MHP1
MAP-homologous protein 1

1

0

High-throughput

0.249

Low

522463

H3
Histone H3

1

0

Small-scale

0.249

Low

522473

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.249

Low

522452

KPR3
Ribose-phosphate pyrophosphokinase 3

1

0

High-throughput

0.232

Low

522458

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024