Protein: GLCNE
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (UDP-GlcNAc-2-epimerase/ManAc kinase) [Includes: UDP-N-acetylglucosamine 2-epimerase (hydrolyzing) (EC 3.2.1.183) (UDP-GlcNAc-2-epimerase) (Uridine diphosphate-N-acetylglucosamine-2-epimerase); N-acetylmannosamine kinase (EC 2.7.1.60) (ManAc kinase)]

Gene: GLCNE, GNE
Organism: Homo sapiens
Interactions: 96
UniProt ID: Q9Y223

Gene Ontology (top 5):
GO:0004396 - hexokinase activity
GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006045 - N-acetylglucosamine biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1376968

GLCNE
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase

1

3

High-throughput

0.698

High

642183

KRA59
Keratin-associated protein 5-9

3

15

High-throughput

0.675

High

889436

KR107
Keratin-associated protein 10-7

3

13

High-throughput

0.675

High

889727

KR108
Keratin-associated protein 10-8

3

13

High-throughput

0.675

High

1071447

K1H1
Keratin, type I cuticular Ha1

3

5

High-throughput

0.675

High

1317284

KRA92
Keratin-associated protein 9-2

3

14

High-throughput

0.675

High

1189490

NT2NA
Notch homolog 2 N-terminal-like protein A

3

1

High-throughput

0.609

High

208405

SPY1
Protein sprouty homolog 1

2

2

High-throughput

0.606

High

208436

SPY3
Protein sprouty homolog 3

2

2

High-throughput

0.606

High

213985

KRT86
Keratin, type II cuticular Hb6

2

2

High-throughput

0.606

High

280755

KRT34
Keratin, type I cuticular Ha4

2

5

High-throughput

0.606

High

943663

KRT83
Keratin, type II cuticular Hb3

2

2

High-throughput

0.606

High

943706

KRT85
Keratin, type II cuticular Hb5

2

2

High-throughput

0.606

High

991691

KRA11
Keratin-associated protein 1-1

2

13

High-throughput

0.606

High

1110286

KR133
Keratin-associated protein 13-3

2

1

High-throughput

0.606

High

1119883

KR132
Keratin-associated protein 13-2

2

1

High-throughput

0.606

High

1149402

K1C40
Keratin, type I cytoskeletal 40

2

5

High-throughput

0.606

High

1216410

KRA13
Keratin-associated protein 1-3

2

15

High-throughput

0.606

High

1317233

KRA98
Keratin-associated protein 9-8

2

14

High-throughput

0.606

High

1317265

KRA93
Keratin-associated protein 9-3

2

14

High-throughput

0.606

High

1317305

KR411
Keratin-associated protein 4-11

2

15

High-throughput

0.606

High

1317309

KRA41
Keratin-associated protein 4-1

2

14

High-throughput

0.606

High

1317330

KRA44
Keratin-associated protein 4-4

2

15

High-throughput

0.606

High

1317360

KRA33
Keratin-associated protein 3-3

2

1

High-throughput

0.606

High

1317385

KRA31
Keratin-associated protein 3-1

2

1

High-throughput

0.606

High

1293126

ZN764
Zinc finger protein 764

2

0

High-throughput

0.602

High

537136

TRI27
Zinc finger protein RFP

2

0

High-throughput

0.580

High

888631

KR123
Keratin-associated protein 12-3

2

0

High-throughput

0.580

High

1076571

TRIP6
Thyroid receptor-interacting protein 6

2

0

High-throughput

0.580

High

1109099

KR192
Keratin-associated protein 19-2

2

0

High-throughput

0.580

High

1109170

KRA61
Keratin-associated protein 6-1

2

0

High-throughput

0.580

High

1109281

KRA62
Keratin-associated protein 6-2

2

0

High-throughput

0.580

High

1110454

KR197
Keratin-associated protein 19-7

2

0

High-throughput

0.580

High

1216029

KR111
Keratin-associated protein 11-1

2

0

High-throughput

0.580

High

1317218

KR171
Keratin-associated protein 17-1

2

0

High-throughput

0.580

High

1349040

WWOX
WW domain-containing oxidoreductase

2

0

High-throughput

0.580

High

995470

LG3BP
Galectin-3-binding protein

2

1

High-throughput

0.574

High

208207

SPY2
Protein sprouty homolog 2

1

2

High-throughput

0.573

High

889923

KR109
Keratin-associated protein 10-9

1

14

High-throughput

0.573

High

1309039

KR412
Keratin-associated protein 4-12

1

15

High-throughput

0.573

High

521642

ACTN1
Alpha-actinin-1

1

0

Small-scale

0.561

High

830058

HXA1
Homeobox protein Hox-A1

2

1

High-throughput

0.553

High

1219926

TRI42
Tripartite motif-containing protein 42

2

2

High-throughput

0.553

High

1310828

WDR83
WD repeat domain-containing protein 83

2

1

High-throughput

0.553

High

1355436

EGFL7
Epidermal growth factor-like protein 7

2

2

High-throughput

0.553

High

1282770

GTPB3
tRNA modification GTPase GTPBP3, mitochondrial

1

0

High-throughput

0.549

High

889137

KR105
Keratin-associated protein 10-5

1

14

High-throughput

0.515

High

154572

ZN213
Zinc finger protein 213

1

0

High-throughput

0.513

High

282262

SEGN
Secretagogin

1

0

High-throughput

0.513

High

1345624

CENPM
Centromere protein M

1

0

High-throughput

0.513

High

1109371

KRA63
Keratin-associated protein 6-3

1

0

High-throughput

0.493

High

960064

HXC5
Homeobox protein Hox-C5

1

1

High-throughput

0.489

High

889030

KR103
Keratin-associated protein 10-3

1

14

High-throughput

0.481

High

484739

NT2NC
Notch homolog 2 N-terminal-like protein C

1

1

High-throughput

0.470

High

1217213

Q8IV28
NID2 protein

1

1

High-throughput

0.470

High

375105

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

385737

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

652632

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

875445

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

882646

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.458

High

983271

UBE3A
Ubiquitin-protein ligase E3A

1

0

High-throughput

0.458

High

999226

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

1042863

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1189058

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1281483

FBXW7
F-box/WD repeat-containing protein 7

1

0

High-throughput

0.458

High

1354890

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1048433

NID2
Nidogen-2

1

1

High-throughput

0.439

High

1259576

SRB4D
Scavenger receptor cysteine-rich domain-containing group B protein

1

1

High-throughput

0.439

High

1172310

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

422119

LDHB
L-lactate dehydrogenase B chain

1

0

Small-scale

0.426

High

1167008

ATL4
ADAMTS-like protein 4

3

0

High-throughput

0.352

High

1102086

CB068
UPF0561 protein C2orf68

3

0

High-throughput

0.347

High

660762

GRN
Progranulin

3

0

High-throughput

0.344

High

67403

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

156168

TSN4
Tetraspanin-4

2

0

High-throughput

0.316

High

180764

PA2GX
Group 10 secretory phospholipase A2

2

0

High-throughput

0.316

High

655101

PROP
Properdin

2

0

High-throughput

0.316

High

1083790

ECM1
Extracellular matrix protein 1

2

0

High-throughput

0.316

High

1102908

VWC2
Brorin

2

0

High-throughput

0.316

High

1134448

KPRP
Keratinocyte proline-rich protein

2

0

High-throughput

0.316

High

1160236

CV039
Synaptic plasticity regulator PANTS

2

0

High-throughput

0.316

High

1306296

MDFI
MyoD family inhibitor

2

0

High-throughput

0.316

High

1114394

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

0

High-throughput

0.279

Low

1246240

GA2L2
GAS2-like protein 2

1

0

High-throughput

0.279

Low

281953

WFS1
Wolframin

1

0

High-throughput

0.268

Low

656

NBPFJ
Neuroblastoma breakpoint family member 19

1

0

High-throughput

0.251

Low

1103198

PRIC4
Prickle-like protein 4

1

0

High-throughput

0.251

Low

1113778

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.251

Low

348265

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.249

Low

391260

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.249

Low

554080

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

721805

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1239347

KDF1
Keratinocyte differentiation factor 1

1

0

High-throughput

0.249

Low

1270534

HDAC2
Histone deacetylase 2

1

0

High-throughput

0.249

Low

1331653

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024