Protein: NT2NC
Notch homolog 2 N-terminal-like protein C

Gene: NT2NC, NOTCH2NLC
Organism: Homo sapiens
Interactions: 217
UniProt ID: P0DPK4

Gene Ontology (top 5):
GO:0005509 - calcium ion binding
GO:0005576 - extracellular region
GO:0007219 - Notch signaling pathway
GO:0021987 - cerebral cortex development
GO:0045747 - positive regulation of Notch signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

240177

KLK8
Kallikrein-8

1

20

High-throughput

0.665

High

366276

FA10
Coagulation factor X

1

9

High-throughput

0.665

High

516981

BCAM
Basal cell adhesion molecule

1

20

High-throughput

0.665

High

516959

PVR
Poliovirus receptor

1

20

High-throughput

0.594

High

516960

ITB4
Integrin beta-4

1

10

High-throughput

0.594

High

517034

VASN
Vasorin

1

9

High-throughput

0.594

High

517043

LRFN4
Leucine-rich repeat and fibronectin type-III domain-containing protein 4

1

6

High-throughput

0.594

High

517055

TRI42
Tripartite motif-containing protein 42

1

14

High-throughput

0.594

High

517076

NECT2
Nectin-2

1

20

High-throughput

0.594

High

517096

TPSNR
Tapasin-related protein

1

19

High-throughput

0.594

High

517109

HPLN2
Hyaluronan and proteoglycan link protein 2

1

5

High-throughput

0.594

High

517119

NECT3
Nectin-3

1

20

High-throughput

0.594

High

209871

ADA12
Disintegrin and metalloproteinase domain-containing protein 12

1

11

High-throughput

0.515

High

350678

NOE2
Noelin-2

1

5

High-throughput

0.515

High

377373

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

1

High-throughput

0.515

High

449481

CRF
Corticoliberin

1

1

High-throughput

0.515

High

472157

TRFM
Melanotransferrin

1

2

High-throughput

0.515

High

479593

DOPO
Dopamine beta-hydroxylase

1

1

High-throughput

0.515

High

479754

GSTP1
Glutathione S-transferase P

1

1

High-throughput

0.515

High

516958

PERF
Perforin-1

1

2

High-throughput

0.515

High

516962

BMP7
Bone morphogenetic protein 7

1

6

High-throughput

0.515

High

516964

AGT1
Alanine--glyoxylate aminotransferase

1

1

High-throughput

0.515

High

516966

IL10
Interleukin-10

1

1

High-throughput

0.515

High

516969

CO8A1
Collagen alpha-1(VIII) chain

1

2

High-throughput

0.515

High

516974

HPCL1
Hippocalcin-like protein 1

1

1

High-throughput

0.515

High

516976

NMU
Neuromedin-U [Cleaved into: Neuromedin precursor-related peptide 36

1

1

High-throughput

0.515

High

516991

HBA
Hemoglobin subunit alpha

1

3

High-throughput

0.515

High

516995

MUC24
Sialomucin core protein 24

1

1

High-throughput

0.515

High

517000

SEM3B
Semaphorin-3B

1

10

High-throughput

0.515

High

517004

ICAM4
Intercellular adhesion molecule 4

1

1

High-throughput

0.515

High

517014

CRY2
Cryptochrome-2

1

2

High-throughput

0.515

High

517045

ATL4
ADAMTS-like protein 4

1

12

High-throughput

0.515

High

517049

R4RL1
Reticulon-4 receptor-like 1

1

3

High-throughput

0.515

High

517075

DOCK2
Dedicator of cytokinesis protein 2

1

5

High-throughput

0.515

High

517077

PCSK5
Proprotein convertase subtilisin/kexin type 5

1

19

High-throughput

0.515

High

517113

NET4
Netrin-4

1

20

High-throughput

0.515

High

517127

NTRI
Neurotrimin

1

12

High-throughput

0.515

High

517130

CATZ
Cathepsin Z

1

2

High-throughput

0.515

High

517132

TEFF2
Tomoregulin-2

1

14

High-throughput

0.515

High

159035

LCE2B
Late cornified envelope protein 2B

1

1

High-throughput

0.483

High

517104

KRA44
Keratin-associated protein 4-4

1

20

High-throughput

0.483

High

59943

A2BDE7
PHLDA1 protein

1

2

High-throughput

0.470

High

61840

F221A
Protein FAM221A

1

1

High-throughput

0.470

High

70099

CRTP1
Cysteine-rich tail protein 1

1

2

High-throughput

0.470

High

165163

TSN4
Tetraspanin-4

1

10

High-throughput

0.470

High

220218

FRS3
Fibroblast growth factor receptor substrate 3

1

1

High-throughput

0.470

High

221311

SPY1
Protein sprouty homolog 1

1

3

High-throughput

0.470

High

246212

MABP1
Mitogen-activated protein kinase-binding protein 1

1

4

High-throughput

0.470

High

260826

RAMP3
Receptor activity-modifying protein 3

1

1

High-throughput

0.470

High

291746

STK16
Serine/threonine-protein kinase 16

1

5

High-throughput

0.470

High

303213

S22A5
Organic cation/carnitine transporter 2

1

7

High-throughput

0.470

High

350212

FADS2
Acyl-CoA 6-desaturase

1

1

High-throughput

0.470

High

364112

MOS
Proto-oncogene serine/threonine-protein kinase mos

1

1

High-throughput

0.470

High

380688

HBAZ
Hemoglobin subunit zeta

1

3

High-throughput

0.470

High

424052

ITB2
Integrin beta-2

1

18

High-throughput

0.470

High

426043

PPB1
Alkaline phosphatase, placental type

1

4

High-throughput

0.470

High

458182

ACHG
Acetylcholine receptor subunit gamma

1

1

High-throughput

0.470

High

473352

HCK
Tyrosine-protein kinase HCK

1

9

High-throughput

0.470

High

479912

CYTT
Cystatin-SA

1

7

High-throughput

0.470

High

506711

PRR35
Proline-rich protein 35

1

1

High-throughput

0.470

High

516961

HXB9
Homeobox protein Hox-B9

1

12

High-throughput

0.470

High

516963

ITB5
Integrin beta-5

1

15

High-throughput

0.470

High

516965

DRD5
D(1B) dopamine receptor

1

2

High-throughput

0.470

High

516967

PSA1
Proteasome subunit alpha type-1

1

2

High-throughput

0.470

High

516968

KRA59
Keratin-associated protein 5-9

1

20

High-throughput

0.470

High

516970

AQP1
Aquaporin-1

1

2

High-throughput

0.470

High

516971

ATPD
ATP synthase F(1) complex subunit delta, mitochondrial

1

1

High-throughput

0.470

High

516972

HXC8
Homeobox protein Hox-C8

1

15

High-throughput

0.470

High

516973

OTX1
Homeobox protein OTX1

1

3

High-throughput

0.470

High

516975

GLP1R
Glucagon-like peptide 1 receptor

1

3

High-throughput

0.470

High

516977

TTPA
Alpha-tocopherol transfer protein

1

3

High-throughput

0.470

High

516978

HXA1
Homeobox protein Hox-A1

1

11

High-throughput

0.470

High

516979

MCSP
Sperm mitochondrial-associated cysteine-rich protein

1

1

High-throughput

0.470

High

516980

MXI1
Max-interacting protein 1

1

7

High-throughput

0.470

High

516982

DGKQ
Diacylglycerol kinase theta

1

2

High-throughput

0.470

High

516983

KR121
Keratin-associated protein 12-1

1

5

High-throughput

0.470

High

516984

KR122
Keratin-associated protein 12-2

1

20

High-throughput

0.470

High

516985

KR10A
Keratin-associated protein 10-10

1

20

High-throughput

0.470

High

516986

KR123
Keratin-associated protein 12-3

1

5

High-throughput

0.470

High

516987

KR124
Keratin-associated protein 12-4

1

1

High-throughput

0.470

High

516988

KR105
Keratin-associated protein 10-5

1

20

High-throughput

0.470

High

516989

KR108
Keratin-associated protein 10-8

1

20

High-throughput

0.470

High

516990

KR109
Keratin-associated protein 10-9

1

20

High-throughput

0.470

High

516992

KRT83
Keratin, type II cuticular Hb3

1

1

High-throughput

0.470

High

516993

CREB5
Cyclic AMP-responsive element-binding protein 5

1

3

High-throughput

0.470

High

516994

HHEX
Hematopoietically-expressed homeobox protein HHEX

1

6

High-throughput

0.470

High

516996

TLE5
TLE family member 5

1

3

High-throughput

0.470

High

516997

Q08AG9
Steroid 21-hydroxylase

1

1

High-throughput

0.470

High

516998

BRME1
Break repair meiotic recombinase recruitment factor 1

1

1

High-throughput

0.470

High

516999

TROAP
Tastin

1

1

High-throughput

0.470

High

517001

PTK7
Inactive tyrosine-protein kinase 7

1

11

High-throughput

0.470

High

517002

MTA1
Metastasis-associated protein MTA1

1

8

High-throughput

0.470

High

517003

CASL
Enhancer of filamentation 1

1

5

High-throughput

0.470

High

517005

MF13A
Transmembrane protein 180

1

1

High-throughput

0.470

High

517006

JOS1
Josephin-1

1

1

High-throughput

0.470

High

517007

P2RY6
P2Y purinoceptor 6

1

2

High-throughput

0.470

High

517008

ZN124
Zinc finger protein 124

1

20

High-throughput

0.470

High

517009

KLH38
Kelch-like protein 38

1

4

High-throughput

0.470

High

517010

KR134
Keratin-associated protein 13-4

1

7

High-throughput

0.470

High

517011

KR133
Keratin-associated protein 13-3

1

7

High-throughput

0.470

High

517012

PKHN1
Pleckstrin homology domain-containing family N member 1

1

1

High-throughput

0.470

High

517013

ZN672
Zinc finger protein 672

1

10

High-throughput

0.470

High

517015

Q49AR9
ANKS1A protein

1

12

High-throughput

0.470

High

517016

KR132
Keratin-associated protein 13-2

1

7

High-throughput

0.470

High

517017

DALD3
DALR anticodon-binding domain-containing protein 3

1

1

High-throughput

0.470

High

517018

LCE3C
Late cornified envelope protein 3C

1

1

High-throughput

0.470

High

517019

LCE3E
Late cornified envelope protein 3E

1

6

High-throughput

0.470

High

517020

ZN648
Zinc finger protein 648

1

17

High-throughput

0.470

High

517021

KPRP
Keratinocyte proline-rich protein

1

1

High-throughput

0.470

High

517022

LCE1D
Late cornified envelope protein 1D

1

1

High-throughput

0.470

High

517023

LCE1E
Late cornified envelope protein 1E

1

1

High-throughput

0.470

High

517024

LCE1F
Late cornified envelope protein 1F

1

1

High-throughput

0.470

High

517025

LCE1A
Late cornified envelope protein 1A

1

1

High-throughput

0.470

High

517026

LCE1B
Late cornified envelope protein 1B

1

1

High-throughput

0.470

High

517027

LCE3A
Late cornified envelope protein 3A

1

3

High-throughput

0.470

High

517028

LCE4A
Late cornified envelope protein 4A

1

1

High-throughput

0.470

High

517029

LCE2C
Late cornified envelope protein 2C

1

5

High-throughput

0.470

High

517030

LCE2D
Late cornified envelope protein 2D

1

5

High-throughput

0.470

High

517031

LCE5A
Late cornified envelope protein 5A

1

1

High-throughput

0.470

High

517032

TENS2
Tensin-2

1

4

High-throughput

0.470

High

517033

WDR25
WD repeat-containing protein 25

1

9

High-throughput

0.470

High

517035

GLYAT
Glycine N-acyltransferase

1

1

High-throughput

0.470

High

517036

KR511
Keratin-associated protein 5-11

1

20

High-throughput

0.470

High

517037

KRA56
Keratin-associated protein 5-6

1

1

High-throughput

0.470

High

517038

KRA54
Keratin-associated protein 5-4

1

20

High-throughput

0.470

High

517039

KRA53
Keratin-associated protein 5-3

1

20

High-throughput

0.470

High

517040

Q6NSM0
NR1D2 protein

1

9

High-throughput

0.470

High

517041

Q6P9E2
RECK protein

1

2

High-throughput

0.470

High

517042

KR261
Keratin-associated protein 26-1

1

1

High-throughput

0.470

High

517044

SPAT8
Spermatogenesis-associated protein 8

1

1

High-throughput

0.470

High

517046

ZN497
Zinc finger protein 497

1

11

High-throughput

0.470

High

517047

ATG9A
Autophagy-related protein 9A

1

2

High-throughput

0.470

High

517048

T150A
Transmembrane protein 150A

1

1

High-throughput

0.470

High

517050

MYPOP
Myb-related transcription factor, partner of profilin

1

3

High-throughput

0.470

High

517051

SPA24
Spermatogenesis-associated protein 24

1

1

High-throughput

0.470

High

517052

AROS
Active regulator of SIRT1

1

1

High-throughput

0.470

High

517053

F90A1
Protein FAM90A1

1

1

High-throughput

0.470

High

517054

SPP2C
Signal peptide peptidase-like 2C

1

1

High-throughput

0.470

High

517056

LMTD2
Lamin tail domain-containing protein 2

1

1

High-throughput

0.470

High

517057

ZN440
Zinc finger protein 440

1

17

High-throughput

0.470

High

517058

A16A1
Aldehyde dehydrogenase family 16 member A1

1

2

High-throughput

0.470

High

517059

LAT4
Large neutral amino acids transporter small subunit 4

1

1

High-throughput

0.470

High

517060

ZN786
Zinc finger protein 786

1

9

High-throughput

0.470

High

517061

MACOI
Macoilin

1

1

High-throughput

0.470

High

517062

CELF5
CUGBP Elav-like family member 5

1

2

High-throughput

0.470

High

517063

DGLB
Diacylglycerol lipase-beta

1

1

High-throughput

0.470

High

517064

CNNM3
Metal transporter CNNM3

1

1

High-throughput

0.470

High

517065

CTSR1
Cation channel sperm-associated protein 1

1

8

High-throughput

0.470

High

517066

GAR6
Golgi-associated RAB2 interactor protein 6

1

2

High-throughput

0.470

High

517067

ZN417
Zinc finger protein 417

1

13

High-throughput

0.470

High

517068

LNX1
E3 ubiquitin-protein ligase LNX

1

10

High-throughput

0.470

High

517069

R3GEF
Guanine nucleotide exchange factor for Rab-3A

1

1

High-throughput

0.470

High

517070

CCER1
Coiled-coil domain-containing glutamate-rich protein 1

1

1

High-throughput

0.470

High

517071

CERK1
Ceramide kinase

1

2

High-throughput

0.470

High

517072

ZDHC1
Palmitoyltransferase ZDHHC1

1

3

High-throughput

0.470

High

517073

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

1

1

High-throughput

0.470

High

517074

TPC14
Trafficking protein particle complex subunit 14

1

1

High-throughput

0.470

High

517078

SC5A5
Sodium/iodide cotransporter

1

2

High-throughput

0.470

High

517079

FBXW5
F-box/WD repeat-containing protein 5

1

1

High-throughput

0.470

High

517080

ZN837
Zinc finger protein 837

1

11

High-throughput

0.470

High

517081

ZN414
Zinc finger protein 414

1

1

High-throughput

0.470

High

517082

MY15B
Unconventional myosin-XVB

1

2

High-throughput

0.470

High

517083

TNIP3
TNFAIP3-interacting protein 3

1

2

High-throughput

0.470

High

517084

DHRS1
Dehydrogenase/reductase SDR family member 1

1

2

High-throughput

0.470

High

517085

HS12B
Heat shock 70 kDa protein 12B

1

1

High-throughput

0.470

High

517086

PIGS
GPI-anchor transamidase component PIGS

1

1

High-throughput

0.470

High

517087

KCD15
BTB/POZ domain-containing protein KCTD15

1

4

High-throughput

0.470

High

517088

ZN587
Zinc finger protein 587

1

13

High-throughput

0.470

High

517089

STAC
SH3 and cysteine-rich domain-containing protein

1

7

High-throughput

0.470

High

517090

P2RX4
P2X purinoceptor 4

1

4

High-throughput

0.470

High

517091

P2RX7
P2X purinoceptor 7

1

4

High-throughput

0.470

High

517092

UTP23
rRNA-processing protein UTP23 homolog

1

2

High-throughput

0.470

High

517093

THAP7
THAP domain-containing protein 7

1

3

High-throughput

0.470

High

517094

MAD3
Max dimerization protein 3

1

7

High-throughput

0.470

High

517095

SCNM1
Sodium channel modifier 1

1

1

High-throughput

0.470

High

517097

FHL17
Ferritin heavy polypeptide-like 17

1

1

High-throughput

0.470

High

517098

LCE3D
Late cornified envelope protein 3D

1

6

High-throughput

0.470

High

517099

KRA98
Keratin-associated protein 9-8

1

20

High-throughput

0.470

High

517100

KRA93
Keratin-associated protein 9-3

1

20

High-throughput

0.470

High

517101

KRA92
Keratin-associated protein 9-2

1

20

High-throughput

0.470

High

517102

KR411
Keratin-associated protein 4-11

1

20

High-throughput

0.470

High

517103

KRA45
Keratin-associated protein 4-5

1

20

High-throughput

0.470

High

517105

KRA42
Keratin-associated protein 4-2

1

20

High-throughput

0.470

High

517106

KRA24
Keratin-associated protein 2-4

1

20

High-throughput

0.470

High

517107

IN80B
INO80 complex subunit B

1

1

High-throughput

0.470

High

517108

SEM4C
Semaphorin-4C

1

10

High-throughput

0.470

High

517110

CHRD
Chordin

1

20

High-throughput

0.470

High

517111

CST9L
Cystatin-9-like

1

7

High-throughput

0.470

High

517112

ZN408
Zinc finger protein 408

1

19

High-throughput

0.470

High

517114

PGAP6
Post-GPI attachment to proteins factor 6

1

1

High-throughput

0.470

High

517115

S6A20
Sodium- and chloride-dependent transporter XTRP3

1

3

High-throughput

0.470

High

517116

EMC7
Endoplasmic reticulum membrane protein complex subunit 7

1

1

High-throughput

0.470

High

517117

RM40
Large ribosomal subunit protein mL40

1

1

High-throughput

0.470

High

517118

DMRT3
Doublesex- and mab-3-related transcription factor 3

1

1

High-throughput

0.470

High

517120

NPDC1
Neural proliferation differentiation and control protein 1

1

2

High-throughput

0.470

High

517121

CNBP1
Beta-catenin-interacting protein 1

1

1

High-throughput

0.470

High

517122

SHFL
Shiftless antiviral inhibitor of ribosomal frameshifting protein

1

2

High-throughput

0.470

High

517123

MRGBP
MRG/MORF4L-binding protein

1

1

High-throughput

0.470

High

517124

ZN446
Zinc finger protein 446

1

19

High-throughput

0.470

High

517125

MIC19
MICOS complex subunit MIC19

1

1

High-throughput

0.470

High

517126

ZN581
Zinc finger protein 581

1

20

High-throughput

0.470

High

517128

ZN319
Zinc finger protein 319

1

10

High-throughput

0.470

High

517129

UXT
Protein UXT

1

1

High-throughput

0.470

High

517131

S23A1
Solute carrier family 23 member 1

1

1

High-throughput

0.470

High

517133

ZN580
Zinc finger protein 580

1

20

High-throughput

0.470

High

517134

CHIC2
Cysteine-rich hydrophobic domain-containing protein 2

1

1

High-throughput

0.470

High

517135

KCNS2
Delayed-rectifier potassium channel regulatory subunit KCNS2

1

2

High-throughput

0.470

High

517136

FZD10
Frizzled-10

1

2

High-throughput

0.470

High

517137

SPG7
Mitochondrial inner membrane m-AAA protease component paraplegin

1

4

High-throughput

0.470

High

517138

GLCNE
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase

1

1

High-throughput

0.470

High

517139

RASD1
Dexamethasone-induced Ras-related protein 1

1

4

High-throughput

0.470

High

517140

R3HD2
R3H domain-containing protein 2

1

6

High-throughput

0.470

High

517141

CHSP1
Calcium-regulated heat-stable protein 1

1

1

High-throughput

0.470

High

517142

ZN330
Zinc finger protein 330

1

1

High-throughput

0.470

High

517143

TCAF1
TRPM8 channel-associated factor 1

1

2

High-throughput

0.470

High

517144

LYVE1
Lymphatic vessel endothelial hyaluronic acid receptor 1

1

5

High-throughput

0.470

High

516957

TM276
Transmembrane protein 276

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025