Protein: TSC11
Target of rapamycin complex 2 subunit TSC11 (TORC2 subunit TSC11) (Adheres voraciously to TOR2 protein 3) (Temperature-sensitive CSG2 suppressor protein 11)

Gene: TSC11
Organism: Saccharomyces cerevisiae S288C
Interactions: 124
UniProt ID: P40061

Gene Ontology (top 5):
GO:0001558 - regulation of cell growth
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005774 - vacuolar membrane
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

696504

TOR2
Serine/threonine-protein kinase TOR2

13

9

Small-scale

0.980

High

767512

LST8
Target of rapamycin complex subunit LST8

4

5

Small-scale

0.694

High

767546

AVO2
Target of rapamycin complex 2 subunit AVO2

4

6

Small-scale

0.683

High

767520

BIT61
Target of rapamycin complex 2 subunit BIT61

4

1

Small-scale

0.677

High

767557

AVO1
Target of rapamycin complex 2 subunit AVO1

4

0

Small-scale

0.653

High

767503

TSC11
Target of rapamycin complex 2 subunit TSC11

1

1

High-throughput

0.618

High

767507

SLM1
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1

3

0

Small-scale

0.613

High

539356

KSS1
Mitogen-activated protein kinase KSS1

2

2

High-throughput

0.574

High

491362

HSP71
Heat shock protein SSA1

2

2

High-throughput

0.571

High

494082

HSP72
Heat shock protein SSA2

2

2

High-throughput

0.571

High

511480

SSB1
Ribosome-associated molecular chaperone SSB1

2

2

High-throughput

0.571

High

748917

BIT2
Probable target of rapamycin complex 2 subunit BIT2

1

1

High-throughput

0.541

High

520613

YPK1
Serine/threonine-protein kinase YPK1

1

8

High-throughput

0.536

High

767534

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

2

Small-scale

0.501

High

514989

RNA1
Ran GTPase-activating protein 1

1

1

High-throughput

0.481

High

690316

CDC11
Cell division control protein 11

1

1

High-throughput

0.481

High

696771

PEP7
Vacuolar segregation protein PEP7

1

1

High-throughput

0.481

High

701261

VAM7
Vacuolar morphogenesis protein 7

1

1

High-throughput

0.481

High

759225

END3
Actin cytoskeleton-regulatory complex protein END3

1

1

High-throughput

0.481

High

764844

SNF7
Vacuolar-sorting protein SNF7

1

2

High-throughput

0.481

High

767513

BNI1
Protein BNI1

1

2

High-throughput

0.481

High

767521

SNX4
Sorting nexin-4

1

1

High-throughput

0.481

High

767541

SNX41
Sorting nexin-41

1

2

High-throughput

0.481

High

767543

VPS20
Vacuolar protein sorting-associated protein 20

1

2

High-throughput

0.481

High

767555

LUC7
Protein LUC7

1

1

High-throughput

0.481

High

767560

NYV1
Vacuolar v-SNARE NYV1

1

1

High-throughput

0.481

High

767566

VPS5
Vacuolar protein sorting-associated protein 5

1

1

High-throughput

0.481

High

634952

STP22
Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease

1

0

High-throughput

0.460

High

639231

MSH1
DNA mismatch repair protein MSH1, mitochondrial

1

0

High-throughput

0.460

High

755139

LAM4
Membrane-anchored lipid-binding protein LAM4

1

0

High-throughput

0.460

High

767506

NUP82
Nucleoporin NUP82

1

0

High-throughput

0.460

High

767509

SA185
SIT4-associating protein SAP185

1

0

High-throughput

0.460

High

767514

SPR3
Sporulation-regulated protein 3

1

0

High-throughput

0.460

High

767542

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.460

High

767553

HDA2
HDA1 complex subunit 2

1

0

High-throughput

0.460

High

767562

GYP5
GTPase-activating protein GYP5

1

0

High-throughput

0.460

High

767540

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

767554

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

366362

HSP82
ATP-dependent molecular chaperone HSP82

1

5

High-throughput

0.445

High

543820

HSC82
ATP-dependent molecular chaperone HSC82

1

5

High-throughput

0.445

High

628109

SIS1
Protein SIS1

1

1

High-throughput

0.445

High

633258

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

694788

HSP7F
Heat shock protein homolog SSE1

1

4

High-throughput

0.445

High

767504

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

446165

MYO1
Myosin-1

1

3

High-throughput

0.439

High

514564

BIK1
Nuclear fusion protein BIK1

1

3

High-throughput

0.439

High

603313

SNF2
Transcription regulatory protein SNF2

1

3

High-throughput

0.439

High

605652

KIN3
Serine/threonine-protein kinase KIN3

1

4

High-throughput

0.439

High

703636

PRS6A
26S proteasome regulatory subunit 6A

1

1

High-throughput

0.439

High

706007

NIP80
Protein NIP100

1

5

High-throughput

0.439

High

708002

NUF2
Kinetochore protein NUF2

1

1

High-throughput

0.439

High

710766

CASP
Protein CASP

1

4

High-throughput

0.439

High

731318

DYHC
Dynein heavy chain, cytoplasmic

1

1

High-throughput

0.439

High

767505

TBP6
Probable 26S proteasome subunit YTA6

1

4

High-throughput

0.439

High

767510

MAD1
Spindle assembly checkpoint component MAD1

1

4

High-throughput

0.439

High

767515

GCN20
Protein GCN20

1

3

High-throughput

0.439

High

767529

PRS10
26S proteasome subunit RPT4

1

4

High-throughput

0.439

High

767530

IPI3
Pre-rRNA-processing protein IPI3

1

6

High-throughput

0.439

High

767536

PRS8
26S proteasome regulatory subunit 8 homolog

1

2

High-throughput

0.439

High

767559

NOP53
Ribosome biogenesis protein NOP53

1

1

High-throughput

0.439

High

767558

SRO7
Lethal(2) giant larvae protein homolog SRO7

1

0

High-throughput

0.438

High

415986

DED1
ATP-dependent RNA helicase DED1

1

1

High-throughput

0.437

High

579940

YPK2
Serine/threonine-protein kinase YPK2/YKR2

1

7

Small-scale

0.437

High

612237

HSP12
12 kDa heat shock protein

1

0

High-throughput

0.426

High

541722

SEC63
Protein translocation protein SEC63

1

3

High-throughput

0.407

High

628983

SCJ1
DnaJ-related protein SCJ1

1

1

High-throughput

0.407

High

705230

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.407

High

754445

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.407

High

760738

TCPG
T-complex protein 1 subunit gamma

1

4

High-throughput

0.407

High

760869

TCPD
T-complex protein 1 subunit delta

1

5

High-throughput

0.407

High

761010

TCPZ
T-complex protein 1 subunit zeta

1

4

High-throughput

0.407

High

766029

HSP7E
Heat shock protein SSC3, mitochondrial

1

3

High-throughput

0.407

High

767518

ERJ5
ER-localized J domain-containing protein 5

1

1

High-throughput

0.407

High

767519

STU2
Protein STU2

1

2

High-throughput

0.407

High

767523

TCPQ
T-complex protein 1 subunit theta

1

4

High-throughput

0.407

High

356500

H4
Histone H4

2

0

High-throughput

0.307

High

767526

PFD6
Prefoldin subunit 6

2

0

High-throughput

0.300

High

409998

NOT3
General negative regulator of transcription subunit 3

1

0

High-throughput

0.251

Low

599915

RE107
Recombination protein 107

1

0

High-throughput

0.251

Low

655616

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

0

High-throughput

0.251

Low

702670

TYE7
Transcription factor TYE7

1

0

High-throughput

0.251

Low

728111

BLI1
Biogenesis of lysosome-related organelles complex 1 subunit BLI1

1

0

High-throughput

0.251

Low

728422

YKF0
Uncharacterized protein YKL050C

1

0

High-throughput

0.251

Low

731817

EBP2
rRNA-processing protein EBP2

1

0

High-throughput

0.251

Low

734309

JNM1
Nuclear migration protein JNM1

1

0

High-throughput

0.251

Low

746729

FL2D
Protein MUM2

1

0

High-throughput

0.251

Low

747210

EXO84
Exocyst complex component EXO84

1

0

High-throughput

0.251

Low

747582

ATG14
Autophagy-related protein 14

1

0

High-throughput

0.251

Low

748277

CENPU
Inner kinetochore subunit AME1

1

0

High-throughput

0.251

Low

753565

ETP1
RING finger protein ETP1

1

0

High-throughput

0.251

Low

756650

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.251

Low

763668

MBO1
Gamma tubulin complex adapter SPC72

1

0

High-throughput

0.251

Low

766785

SPC25
Kinetochore protein SPC25

1

0

High-throughput

0.251

Low

767511

CBF3B
Centromere DNA-binding protein complex CBF3 subunit B

1

0

High-throughput

0.251

Low

767516

FMP32
Protein FMP32, mitochondrial

1

0

High-throughput

0.251

Low

767517

BUD27
Bud site selection protein 27

1

0

High-throughput

0.251

Low

767522

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.251

Low

767524

NNF1
Kinetochore-associated protein NNF1

1

0

High-throughput

0.251

Low

767525

MED21
Mediator of RNA polymerase II transcription subunit 21

1

0

High-throughput

0.251

Low

767527

SP105
Spindle pole body component SPC105

1

0

High-throughput

0.251

Low

767528

NNF2
Protein NNF2

1

0

High-throughput

0.251

Low

767532

AF9
Protein AF-9 homolog

1

0

High-throughput

0.251

Low

767533

HSK3
DASH complex subunit HSK3

1

0

High-throughput

0.251

Low

767535

CIK1
Spindle pole body-associated protein CIK1

1

0

High-throughput

0.251

Low

767537

LGE1
Transcriptional regulatory protein LGE1

1

0

High-throughput

0.251

Low

767538

YAP6
AP-1-like transcription factor YAP6

1

0

High-throughput

0.251

Low

767539

SPC19
DASH complex subunit SPC19

1

0

High-throughput

0.251

Low

767545

SPC24
Kinetochore protein SPC24

1

0

High-throughput

0.251

Low

767547

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.251

Low

767548

RPN7
26S proteasome regulatory subunit RPN7

1

0

High-throughput

0.251

Low

767549

NKP2
Inner kinetochore subunit NKP2

1

0

High-throughput

0.251

Low

767550

BL1S4
Biogenesis of lysosome-related organelles complex 1 subunit CNL1

1

0

High-throughput

0.251

Low

767551

NDE1
Nuclear distribution protein nudE homolog 1

1

0

High-throughput

0.251

Low

767552

ARR1
Arsenical-resistance protein ARR1

1

0

High-throughput

0.251

Low

767556

YL031
Putative uncharacterized protein YLR031W

1

0

High-throughput

0.251

Low

767563

NCA2
Nuclear control of ATPase protein 2

1

0

High-throughput

0.251

Low

767565

TMA17
Translation machinery-associated protein 17

1

0

High-throughput

0.251

Low

767567

HPH1
Protein HPH1

1

0

High-throughput

0.251

Low

767508

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

767564

LAS17
Proline-rich protein LAS17

1

0

Small-scale

0.249

Low

767531

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.232

Low

767544

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.232

Low

767561

HSP42
Heat shock protein 42

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024