Protein: SPTC1
Serine palmitoyltransferase 1 (SPT 1) (SPT1) (EC 2.3.1.50) (Long chain base biosynthesis protein 1)

Gene: SPTC1, LCB1
Organism: Saccharomyces cerevisiae S288C
Interactions: 31
UniProt ID: P25045

Gene Ontology (top 5):
GO:0004758 - serine C-palmitoyltransferase activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0030170 - pyridoxal phosphate binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

626000

LCB2
Serine palmitoyltransferase 2

10

9

Small-scale

0.975

High

626008

ORM2
Protein ORM2

8

8

Small-scale

0.971

High

626002

ORM1
Protein ORM1

6

8

Small-scale

0.944

High

626010

TSC3
Serine palmitoyltransferase-regulating protein TSC3

7

1

Small-scale

0.742

High

625993

SAC1
Phosphatidylinositol-3-phosphatase SAC1

7

1

Small-scale

0.742

High

625989

SPTC1
Serine palmitoyltransferase 1

1

9

Small-scale

0.618

High

626001

GPI8
GPI-anchor transamidase

1

0

High-throughput

0.518

High

454197

TBA1
Tubulin alpha-1 chain

1

1

High-throughput

0.489

High

625999

ELO3
Fatty acid elongase 3

1

1

High-throughput

0.479

High

626004

ALG9
Alpha-1,2-mannosyltransferase ALG9

1

0

High-throughput

0.458

High

626006

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.438

High

357210

RMAR
Small ribosomal subunit protein uS3m

1

1

High-throughput

0.437

High

423768

ATPA
ATP synthase subunit alpha, mitochondrial

1

1

High-throughput

0.437

High

543247

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.437

High

597448

PUR6
Phosphoribosylaminoimidazole carboxylase

1

3

High-throughput

0.437

High

625990

SIS1
Protein SIS1

1

1

High-throughput

0.437

High

625991

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

625992

BMH1
Protein BMH1

1

2

High-throughput

0.437

High

625995

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.437

High

625998

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.437

High

626003

HST2
NAD-dependent protein deacetylase HST2

1

2

High-throughput

0.437

High

626007

SCC2
Sister chromatid cohesion protein 2

1

2

High-throughput

0.437

High

493264

HSP72
Heat shock protein SSA2

1

4

High-throughput

0.407

High

510350

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.407

High

625994

HSP7F
Heat shock protein homolog SSE1

1

5

High-throughput

0.407

High

536660

SNA3
Protein SNA3

1

0

High-throughput

0.282

High

625996

MID2
Cell wall integrity sensor MID2

1

0

High-throughput

0.282

High

626009

ESF1
Pre-rRNA-processing protein ESF1

1

0

High-throughput

0.238

Low

625997

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

High-throughput

0.232

Low

626005

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024