Protein: ACO1
Acyl-CoA desaturase 1 (EC 1.14.19.1) (Delta 9 fatty acid desaturase) (Fatty acid desaturase 1) (Stearoyl-CoA desaturase 1)

Gene: ACO1, OLE1
Organism: Saccharomyces cerevisiae S288C
Interactions: 102
UniProt ID: P21147

Gene Ontology (top 5):
GO:0000001 - mitochondrion inheritance
GO:0004768 - stearoyl-CoA 9-desaturase activity
GO:0005506 - iron ion binding
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

596938

ACO1
Acyl-CoA desaturase 1

4

0

Small-scale

0.854

High

541614

SEC63
Protein translocation protein SEC63

2

1

Small-scale

0.757

High

596971

PHO88
SRP-independent targeting protein 3

4

0

High-throughput

0.666

High

596983

CYB5
Cytochrome b5

1

5

High-throughput

0.618

High

596998

HLJ1
Protein HLJ1

1

1

High-throughput

0.618

High

495788

CP51
Lanosterol 14-alpha demethylase CYP51

1

1

High-throughput

0.541

High

596939

ELO2
Fatty acid elongase 2

1

1

High-throughput

0.541

High

597004

TMEDA
Endoplasmic reticulum vesicle protein 25

1

1

High-throughput

0.541

High

596953

OCH1
Initiation-specific alpha-1,6-mannosyltransferase

1

0

High-throughput

0.518

High

596972

MKAR
Very-long-chain 3-oxoacyl-CoA reductase

1

0

High-throughput

0.518

High

596985

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.518

High

596986

SNL1
HSP70 co-chaperone SNL1

1

0

High-throughput

0.518

High

596997

ILM1
Protein ILM1

1

0

High-throughput

0.518

High

597002

ERG5
C-22 sterol desaturase ERG5

1

0

High-throughput

0.518

High

596978

ERP2
Protein ERP2

1

2

High-throughput

0.515

High

596992

SPC1
Signal peptidase complex subunit 1

1

1

High-throughput

0.515

High

596940

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.481

High

596959

GPT1
Glycerol-3-phosphate O-acyltransferase 1

1

1

Small-scale

0.481

High

596969

GPT2
Glycerol-3-phosphate O-acyltransferase 2

1

1

Small-scale

0.481

High

520221

HMDH1
3-hydroxy-3-methylglutaryl-coenzyme A reductase 1

1

1

High-throughput

0.479

High

520310

HMDH2
3-hydroxy-3-methylglutaryl-coenzyme A reductase 2

1

1

High-throughput

0.479

High

596951

PMT2
Dolichyl-phosphate-mannose--protein mannosyltransferase 2

1

2

High-throughput

0.479

High

596979

SPF1
Endoplasmic reticulum transmembrane helix translocase

1

1

High-throughput

0.479

High

596982

SCS2
Vesicle-associated membrane protein-associated protein SCS2

1

1

Small-scale

0.479

High

596984

ELO3
Fatty acid elongase 3

1

1

High-throughput

0.479

High

596993

PMT4
Dolichyl-phosphate-mannose--protein mannosyltransferase 4

1

2

High-throughput

0.479

High

597013

HRD1
ERAD-associated E3 ubiquitin-protein ligase HRD1

1

1

Small-scale

0.479

High

597017

ERP4
Protein ERP4

1

2

High-throughput

0.479

High

596961

PLSC
1-acyl-sn-glycerol-3-phosphate acyltransferase

1

0

Small-scale

0.460

High

597015

DGAT2
Diacylglycerol O-acyltransferase 1

1

0

Small-scale

0.460

High

411161

PIS
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

1

0

High-throughput

0.458

High

596941

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.458

High

596942

CWH43
Protein CWH43

1

0

High-throughput

0.458

High

596955

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

Small-scale

0.458

High

596960

EMP24
Endosomal protein P24B

1

0

High-throughput

0.458

High

596963

SEC66
Translocation protein SEC66

1

0

High-throughput

0.458

High

596968

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

0

High-throughput

0.458

High

596974

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

596975

GPI16
GPI transamidase component GPI16

1

0

High-throughput

0.458

High

596990

ALG2
Alpha-1,3/1,6-mannosyltransferase ALG2

1

0

High-throughput

0.458

High

596991

PHO86
Inorganic phosphate transporter PHO86

1

0

High-throughput

0.458

High

597001

ERG25
C-4 methylsterol oxidase ERG25

1

0

High-throughput

0.458

High

597005

NUM1
Nuclear migration protein NUM1

1

0

High-throughput

0.458

High

597009

CUE4
CUE domain-containing protein CUE4

1

0

High-throughput

0.458

High

597011

GSF2
Glucose-signaling factor 2

1

0

High-throughput

0.458

High

597018

ENV10
SRP-independent targeting protein 2

1

0

High-throughput

0.458

High

477120

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

2

High-throughput

0.457

High

562679

FUS3
Mitogen-activated protein kinase FUS3

1

1

High-throughput

0.457

High

597000

PMT5
Dolichyl-phosphate-mannose--protein mannosyltransferase 5

1

2

High-throughput

0.457

High

596958

ANP1
Mannan polymerase II complex ANP1 subunit

1

1

High-throughput

0.445

High

596977

MNN9
Mannan polymerase complexes subunit MNN9

1

1

High-throughput

0.445

High

596987

HACD
Very-long-chain

1

0

High-throughput

0.438

High

596995

GPI14
GPI mannosyltransferase 1

1

0

High-throughput

0.438

High

490319

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.437

High

596943

TAH1
TPR repeat-containing protein associated with Hsp90

1

1

Small-scale

0.437

High

596952

HS104
Heat shock protein 104

1

1

High-throughput

0.437

High

596962

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.437

High

597003

ORC1
Origin recognition complex subunit 1

1

1

High-throughput

0.437

High

596999

MNN10
Probable alpha-1,6-mannosyltransferase MNN10

1

0

High-throughput

0.426

High

493182

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.407

High

596957

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.407

High

365780

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.282

High

596945

PPZ1
Serine/threonine-protein phosphatase PP-Z1

1

0

High-throughput

0.282

High

596965

MID2
Cell wall integrity sensor MID2

1

0

High-throughput

0.282

High

596967

CAB3
Coenzyme A biosynthesis protein 3

1

0

High-throughput

0.282

High

596947

KCC1
Calcium/calmodulin-dependent protein kinase I

1

0

High-throughput

0.261

Low

596996

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

0

High-throughput

0.261

Low

596948

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

596949

BMH1
Protein BMH1

1

0

High-throughput

0.249

Low

596954

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.249

Low

596956

HOG1
Mitogen-activated protein kinase HOG1

1

0

High-throughput

0.249

Low

596964

YKK0
Probable intramembrane protease YKL100C

1

0

High-throughput

0.249

Low

596970

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

596976

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.249

Low

596988

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.249

Low

596989

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

0

High-throughput

0.249

Low

596994

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.249

Low

597007

GIS1
Transcriptional activator/repressor GIS1

1

0

High-throughput

0.249

Low

597008

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

597010

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.249

Low

597014

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

597016

TPO4
Polyamine transporter 4

1

0

High-throughput

0.238

Low

360735

TBB
Tubulin beta chain

1

0

High-throughput

0.232

Low

376631

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.232

Low

399329

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.232

Low

404493

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.232

Low

407724

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.232

Low

454175

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.232

Low

498791

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.232

Low

510240

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.232

Low

534694

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.232

Low

555807

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.232

Low

596944

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.232

Low

596946

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.232

Low

596950

XPO1
Exportin-1

1

0

High-throughput

0.232

Low

596966

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

High-throughput

0.232

Low

596973

YHI0
Putative proline--tRNA ligase YHR020W

1

0

High-throughput

0.232

Low

596980

GEA2
ARF guanine-nucleotide exchange factor 2

1

0

High-throughput

0.232

Low

596981

IMB4
Importin subunit beta-4

1

0

High-throughput

0.232

Low

597006

CLU
Clustered mitochondria protein 1

1

0

High-throughput

0.232

Low

597012

RRP5
rRNA biogenesis protein RRP5

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024