Protein: EDC3
Enhancer of mRNA-decapping protein 3

Gene: EDC3
Organism: Saccharomyces cerevisiae S288C
Interactions: 72
UniProt ID: P39998

Gene Ontology (top 5):
GO:0000932 - P-body
GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0031087 - deadenylation-independent decapping of nuclear-transcribed mRNA

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

761945

DHH1
ATP-dependent RNA helicase DHH1

8

2

Small-scale

0.972

High

766449

EDC3
Enhancer of mRNA-decapping protein 3

6

2

Small-scale

0.935

High

766466

DCP2
m7GpppN-mRNA hydrolase

16

4

Small-scale

0.764

High

766478

DCP1
mRNA-decapping enzyme subunit 1

7

0

Small-scale

0.714

High

605051

XRN1
5'-3' exoribonuclease 1

4

1

Small-scale

0.692

High

747138

TTL
Probable tubulin--tyrosine ligase PBY1

4

0

Small-scale

0.666

High

471502

RS28B
Small ribosomal subunit protein eS28B

3

1

Small-scale

0.663

High

766462

LSM8
U6 snRNA-associated Sm-like protein LSm8

3

2

High-throughput

0.652

High

766479

RS28A
Small ribosomal subunit protein eS28A

2

1

Small-scale

0.643

High

766459

SCD6
Protein SCD6

2

1

Small-scale

0.619

High

766455

SSB2
Ribosome-associated molecular chaperone SSB2

3

1

High-throughput

0.611

High

676080

XPO1
Exportin-1

2

2

High-throughput

0.606

High

675743

RENT1
ATP-dependent helicase NAM7

2

2

Small-scale

0.586

High

664463

HRR25
Casein kinase I homolog HRR25

2

0

Small-scale

0.585

High

635866

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

2

1

Small-scale

0.584

High

759294

MET30
F-box protein MET30

2

0

High-throughput

0.565

High

494057

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.552

High

368094

EF1A
Elongation factor 1-alpha

2

0

Small-scale

0.547

High

756499

KOG1
Target of rapamycin complex 1 subunit KOG1

1

0

High-throughput

0.529

High

766453

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

0

High-throughput

0.518

High

766473

MYO5
Myosin-5

1

0

High-throughput

0.518

High

766461

LSM1
Sm-like protein LSm1

1

2

High-throughput

0.515

High

766468

LSM3
U6 snRNA-associated Sm-like protein LSm3

1

1

High-throughput

0.515

High

746292

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

2

High-throughput

0.508

High

485527

SSBP1
Single-stranded nucleic acid-binding protein

1

2

Small-scale

0.501

High

565607

PHO85
Cyclin-dependent protein kinase PHO85

1

1

High-throughput

0.501

High

602685

MCK1
Protein kinase MCK1

1

2

High-throughput

0.501

High

766451

EDC2
Enhancer of mRNA-decapping protein 2

1

0

High-throughput

0.493

High

619144

SPT6
Transcription elongation factor SPT6

1

0

High-throughput

0.486

High

710655

SEF1
Putative transcription factor SEF1

1

0

High-throughput

0.486

High

766463

HIR3
Histone transcription regulator 3

1

0

High-throughput

0.486

High

766476

SRL2
Protein SRL2

1

0

High-throughput

0.486

High

412760

KAPA
cAMP-dependent protein kinase type 1

1

0

High-throughput

0.480

High

730809

CENPA
Histone H3-like centromeric protein CSE4

1

1

High-throughput

0.479

High

766469

H3
Histone H3

1

1

High-throughput

0.479

High

399484

RLA0
Large ribosomal subunit protein uL10

1

0

Small-scale

0.458

High

407079

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

407940

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

410391

SC160
Protein SCP160

1

0

Small-scale

0.458

High

498943

RL4A
Large ribosomal subunit protein uL4A

1

0

Small-scale

0.458

High

543801

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.458

High

662319

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

748140

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.458

High

766456

TM108
Protein TMA108

1

0

High-throughput

0.458

High

766457

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

766464

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

766465

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.458

High

766471

EBS1
Nonsense-mediated mRNA decay factor EBS1

1

0

Small-scale

0.458

High

766472

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

766474

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

766475

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.458

High

766477

NMD4
Nonsense-mediated decay protein 4

1

0

Small-scale

0.458

High

491332

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

511436

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

766458

TCPH
T-complex protein 1 subunit eta

1

1

High-throughput

0.445

High

766467

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.438

High

760734

TCPG
T-complex protein 1 subunit gamma

1

1

High-throughput

0.437

High

360891

TBB
Tubulin beta chain

1

0

High-throughput

0.426

High

424536

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

454612

TBA3
Tubulin alpha-3 chain

1

0

High-throughput

0.426

High

478234

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.426

High

556075

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

705220

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.426

High

766460

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

758663

TEM1
Protein TEM1

2

0

High-throughput

0.307

High

710610

SKT5
Chitin synthase regulator SKT5

1

0

High-throughput

0.265

Low

766450

FIR1
Factor interacting with REF2

1

0

High-throughput

0.265

Low

766452

NU157
Nucleoporin NUP157

1

0

High-throughput

0.265

Low

766454

DSE1
Protein DSE1

1

0

High-throughput

0.265

Low

762226

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

766470

NUM1
Nuclear migration protein NUM1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024