Protein: UBP15
Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.4.19.12) (Deubiquitinating enzyme 15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15)

Gene: UBP15
Organism: Saccharomyces cerevisiae S288C
Interactions: 147
UniProt ID: P50101

Gene Ontology (top 5):
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005777 - peroxisome
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

837406

CDH1
APC/C activator protein CDH1

4

16

Small-scale

0.890

High

477365

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

2

20

Small-scale

0.767

High

837410

2ABA
Protein phosphatase PP2A regulatory subunit B

2

0

High-throughput

0.736

High

837427

ECM30
Protein ECM30

8

0

Small-scale

0.715

High

693630

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

18

High-throughput

0.691

High

746816

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

15

High-throughput

0.665

High

767623

GLE2
mRNA export factor GLE2

1

10

High-throughput

0.618

High

837401

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

13

High-throughput

0.618

High

837423

SEC13
Protein transport protein SEC13

1

6

High-throughput

0.618

High

360950

TBB
Tubulin beta chain

2

12

High-throughput

0.611

High

424604

PYR1
Multifunctional protein URA2

2

4

High-throughput

0.611

High

539263

YAK1
Dual specificity protein kinase YAK1

2

12

Small-scale

0.611

High

714899

PEX5
Peroxisomal targeting signal receptor

2

7

Small-scale

0.602

High

817337

ASK10
Activator of SKN7 protein 10

2

1

High-throughput

0.601

High

837407

FPK1
Flippase kinase 1

2

11

Small-scale

0.584

High

837404

SEH1
Nucleoporin SEH1

1

11

High-throughput

0.553

High

707338

PEX6
Peroxisomal ATPase PEX6

1

7

Small-scale

0.552

High

491802

HSP71
Heat shock protein SSA1

2

10

High-throughput

0.552

High

768907

SSB2
Ribosome-associated molecular chaperone SSB2

2

10

High-throughput

0.552

High

762149

YM11
Uncharacterized protein YMR124W

2

0

High-throughput

0.547

High

416025

DED1
ATP-dependent RNA helicase DED1

1

11

High-throughput

0.536

High

701903

SWE1
Mitosis inhibitor protein kinase SWE1

1

12

High-throughput

0.536

High

715355

SPT7
Transcriptional activator SPT7

1

20

High-throughput

0.536

High

757438

SPT8
Transcription factor SPT8

1

1

High-throughput

0.536

High

797817

LSB3
LAS seventeen-binding protein 3

1

5

High-throughput

0.536

High

837408

CBK1
Serine/threonine-protein kinase CBK1

1

8

High-throughput

0.536

High

837435

HSP42
Heat shock protein 42

1

2

High-throughput

0.536

High

585344

MYO2
Myosin-2

1

11

High-throughput

0.515

High

597133

ACE2
Metallothionein expression activator

1

11

High-throughput

0.515

High

602455

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

1

High-throughput

0.515

High

690326

CDC11
Cell division control protein 11

1

2

High-throughput

0.515

High

704604

SEC3
Exocyst complex component SEC3

1

11

High-throughput

0.515

High

766326

SNU13
13 kDa ribonucleoprotein-associated protein

1

5

High-throughput

0.515

High

783847

BUB1
Checkpoint serine/threonine-protein kinase BUB1

1

7

High-throughput

0.515

High

791193

EMW1
Essential for maintenance of the cell wall protein 1

1

6

High-throughput

0.515

High

810874

MTR4
ATP-dependent RNA helicase DOB1

1

17

High-throughput

0.515

High

837403

ALAT
Probable alanine aminotransferase

1

2

High-throughput

0.515

High

837411

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

7

High-throughput

0.515

High

837425

RGC1
Regulator of the glycerol channel 1

1

1

High-throughput

0.515

High

837436

NOP56
Nucleolar protein 56

1

3

High-throughput

0.515

High

597585

FAR1
Cyclin-dependent kinase inhibitor FAR1

1

0

High-throughput

0.513

High

767797

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

0

High-throughput

0.513

High

837429

PRP11
Pre-mRNA-splicing factor PRP11

1

0

High-throughput

0.513

High

412808

KAPA
cAMP-dependent protein kinase type 1

1

7

High-throughput

0.501

High

565692

PHO85
Cyclin-dependent protein kinase PHO85

1

2

High-throughput

0.501

High

673208

CGS5
S-phase entry cyclin-5

1

2

Small-scale

0.501

High

703242

PRP40
Pre-mRNA-processing protein PRP40

1

2

High-throughput

0.501

High

743898

AKL1
Serine/threonine-protein kinase AKL1

1

1

High-throughput

0.501

High

771533

SECU
Securin

1

1

Small-scale

0.501

High

771567

DOA10
ERAD-associated E3 ubiquitin-protein ligase DOA10

1

3

High-throughput

0.501

High

798316

TOS3
Serine/threonine-protein kinase TOS3

1

4

High-throughput

0.501

High

812527

ENT3
Epsin-3

1

3

Small-scale

0.501

High

837419

SKY1
Serine/threonine-protein kinase SKY1

1

20

High-throughput

0.501

High

837420

ENT5
Epsin-5

1

3

Small-scale

0.501

High

837431

ESA1
Histone acetyltransferase ESA1

1

3

Small-scale

0.501

High

622050

SSD1
Protein SSD1

1

0

High-throughput

0.493

High

733759

DRE2
Fe-S cluster assembly protein DRE2

1

0

High-throughput

0.493

High

757060

MNL1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

0

High-throughput

0.493

High

805109

SAC3
Nuclear mRNA export protein SAC3

1

0

High-throughput

0.493

High

812350

YJ68
Uncharacterized protein YJR098C

1

0

High-throughput

0.493

High

375442

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

2

High-throughput

0.479

High

440065

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

2

High-throughput

0.479

High

454398

TBA1
Tubulin alpha-1 chain

1

6

High-throughput

0.479

High

454633

TBA3
Tubulin alpha-3 chain

1

8

High-throughput

0.479

High

530014

STE12
Protein STE12

1

1

Small-scale

0.479

High

544073

HSC82
ATP-dependent molecular chaperone HSC82

1

6

High-throughput

0.479

High

554692

HSP26
Heat shock protein 26

1

2

High-throughput

0.479

High

558149

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

High-throughput

0.479

High

621573

PEX1
Peroxisomal ATPase PEX1

1

8

Small-scale

0.479

High

662745

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

691643

NUP2
Nucleoporin NUP2

1

7

High-throughput

0.479

High

698872

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

4

High-throughput

0.479

High

710344

IF4B
Eukaryotic translation initiation factor 4B

1

4

High-throughput

0.479

High

716466

SPT21
Protein SPT21

1

1

High-throughput

0.479

High

728281

DEF1
RNA polymerase II degradation factor 1

1

4

High-throughput

0.479

High

730856

CENPA
Histone H3-like centromeric protein CSE4

1

9

High-throughput

0.479

High

743596

HMT1
Protein arginine N-methyltransferase 1

1

2

High-throughput

0.479

High

750985

KPR2
Ribose-phosphate pyrophosphokinase 2

1

3

High-throughput

0.479

High

753883

RPN1
26S proteasome regulatory subunit RPN1

1

5

High-throughput

0.479

High

761184

RGA1
Rho-type GTPase-activating protein 1

1

3

High-throughput

0.479

High

762378

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

774361

NU159
Nucleoporin NUP159

1

9

High-throughput

0.479

High

811035

NU192
Nucleoporin NUP192

1

1

High-throughput

0.479

High

819890

CLA4
Serine/threonine-protein kinase CLA4

1

10

Small-scale

0.479

High

837409

APJ1
J domain-containing protein APJ1

1

7

High-throughput

0.479

High

837415

ROD1
Protein ROD1

1

1

Small-scale

0.479

High

837416

IMA1
Importin subunit alpha

1

6

High-throughput

0.479

High

837417

DIG1
Down-regulator of invasive growth 1

1

1

Small-scale

0.479

High

837426

IMB1
Importin subunit beta-1

1

2

High-throughput

0.479

High

837432

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

2

High-throughput

0.479

High

837434

GLE1
mRNA export factor GLE1

1

2

High-throughput

0.479

High

812597

IML1
Vacuolar membrane-associated protein IML1

1

3

High-throughput

0.470

High

816880

NOL10
Ribosome biogenesis protein ENP2

1

1

High-throughput

0.470

High

837405

MLC1
Myosin light chain 1

1

4

High-throughput

0.470

High

566200

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.458

High

576202

TEC1
Ty transcription activator TEC1

1

0

Small-scale

0.458

High

685415

MLF3
Protein MLF3

1

0

Small-scale

0.458

High

697183

PMD1
Negative regulator of sporulation PMD1

1

0

Small-scale

0.458

High

700988

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

710023

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

0

High-throughput

0.458

High

710850

LST4
Protein LST4

1

0

Small-scale

0.458

High

734028

NU133
Nucleoporin NUP133

1

0

High-throughput

0.458

High

745494

ECM21
Protein ECM21

1

0

Small-scale

0.458

High

755493

SBE22
Protein SBE22

1

0

Small-scale

0.458

High

756002

YHT1
PH domain-containing protein YHR131C

1

0

High-throughput

0.458

High

772770

NUP82
Nucleoporin NUP82

1

0

High-throughput

0.458

High

837418

DIG2
Down-regulator of invasive growth 2

1

0

Small-scale

0.458

High

837430

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

837437

HPH1
Protein HPH1

1

0

Small-scale

0.458

High

366579

HSP82
ATP-dependent molecular chaperone HSP82

1

6

High-throughput

0.445

High

368214

EF1A
Elongation factor 1-alpha

1

4

High-throughput

0.445

High

478352

HSP77
Import motor subunit, mitochondrial

1

12

High-throughput

0.445

High

494421

HSP72
Heat shock protein SSA2

1

10

High-throughput

0.445

High

511965

SSB1
Ribosome-associated molecular chaperone SSB1

1

10

High-throughput

0.445

High

556159

VATB
V-type proton ATPase subunit B

1

4

High-throughput

0.445

High

599486

VPS1
Vacuolar protein sorting-associated protein 1

1

2

High-throughput

0.445

High

628262

SIS1
Protein SIS1

1

4

High-throughput

0.445

High

696015

HSP79
Heat shock protein homolog SSE2

1

14

High-throughput

0.445

High

705413

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.445

High

772567

JEM1
DnaJ-like chaperone JEM1

1

6

High-throughput

0.445

High

792384

TCPH
T-complex protein 1 subunit eta

1

11

High-throughput

0.445

High

805314

AP3B
AP-3 complex subunit beta

1

6

High-throughput

0.445

High

810061

PFD1
Prefoldin subunit 1

1

1

High-throughput

0.445

High

829630

RL4B
Large ribosomal subunit protein uL4B

1

1

High-throughput

0.445

High

837428

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

6

High-throughput

0.445

High

837433

RL7B
Large ribosomal subunit protein uL30B

1

3

High-throughput

0.445

High

541898

NSP1
Nucleoporin NSP1

1

11

High-throughput

0.437

High

619609

MPCP
Mitochondrial phosphate carrier protein

1

4

High-throughput

0.437

High

757305

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

3

High-throughput

0.437

High

822979

NUP57
Nucleoporin NUP57

1

8

High-throughput

0.437

High

830665

NU145
Nucleoporin NUP145

1

13

High-throughput

0.437

High

837412

NUP49
Nucleoporin NUP49/NSP49

1

7

High-throughput

0.437

High

837413

NU100
Nucleoporin NUP100/NSP100

1

10

High-throughput

0.437

High

837414

NU116
Nucleoporin NUP116/NSP116

1

10

High-throughput

0.437

High

837421

NUP53
Nucleoporin NUP53

1

1

High-throughput

0.437

High

837424

NUP59
Nucleoporin ASM4

1

1

High-throughput

0.437

High

704487

DHE2
NAD-specific glutamate dehydrogenase

1

0

High-throughput

0.269

Low

707174

PAD1
Flavin prenyltransferase PAD1, mitochondrial

1

0

High-throughput

0.269

Low

746115

YBE4
Uncharacterized protein YBL044W

1

0

High-throughput

0.269

Low

709331

NIC96
Nucleoporin NIC96

1

0

High-throughput

0.249

Low

728199

NU120
Nucleoporin NUP120

1

0

High-throughput

0.249

Low

745764

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

746104

RRT1
Regulator of rDNA transcription protein 1

1

0

High-throughput

0.249

Low

805082

NUP85
Nucleoporin NUP85

1

0

High-throughput

0.249

Low

837402

NU188
Nucleoporin NUP188

1

0

High-throughput

0.249

Low

837422

YM35
Uncharacterized protein YMR160W

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024