Protein: GATA1
Erythroid transcription factor (Eryf1) (GATA-binding factor 1) (GATA-1) (GF-1) (NF-E1 DNA-binding protein)

Gene: GATA1
Organism: Homo sapiens
Interactions: 174
UniProt ID: P15976

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

554455

TRIP6
Thyroid receptor-interacting protein 6

5

0

High-throughput

0.887

High

554407

RBTN2
Rhombotin-2

1

11

Small-scale

0.740

High

554448

FHL3
Four and a half LIM domains protein 3

1

1

High-throughput

0.723

High

212356

AAKB2
5'-AMP-activated protein kinase subunit beta-2

5

0

High-throughput

0.697

High

554428

FLI1
Friend leukemia integration 1 transcription factor

3

9

Small-scale

0.683

High

554417

HXA1
Homeobox protein Hox-A1

3

13

High-throughput

0.675

High

554514

DHX36
ATP-dependent DNA/RNA helicase DHX36

3

1

High-throughput

0.667

High

554505

MDFI
MyoD family inhibitor

2

1

High-throughput

0.651

High

554403

SPI1
Transcription factor PU.1

3

14

Small-scale

0.646

High

554464

TENS2
Tensin-2

3

0

High-throughput

0.633

High

388206

HSPB1
Heat shock protein beta-1

2

3

Small-scale

0.631

High

554477

PIAS4
E3 SUMO-protein ligase PIAS4

2

2

Small-scale

0.611

High

554488

FOG2
Zinc finger protein ZFPM2

2

12

Small-scale

0.606

High

554427

PITX1
Pituitary homeobox 1

2

4

High-throughput

0.606

High

554438

TLE5
TLE family member 5

2

10

High-throughput

0.606

High

554465

KANK2
KN motif and ankyrin repeat domain-containing protein 2

2

7

High-throughput

0.606

High

554441

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

2

3

Small-scale

0.595

High

554499

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

2

7

Small-scale

0.595

High

554402

TAL1
T-cell acute lymphocytic leukemia protein 1

2

9

Small-scale

0.586

High

554440

EP300
Histone acetyltransferase p300

2

20

Small-scale

0.584

High

554457

NF2L2
Nuclear factor erythroid 2-related factor 2

1

2

Small-scale

0.582

High

554454

MED1
Mediator of RNA polymerase II transcription subunit 1

1

9

Small-scale

0.581

High

554487

TEKT4
Tektin-4

2

0

High-throughput

0.580

High

554509

DGC6L
Protein DGCR6L

2

0

High-throughput

0.580

High

554522

PLS4
Phospholipid scramblase 4

2

0

High-throughput

0.580

High

554526

FANCL
E3 ubiquitin-protein ligase FANCL

2

0

High-throughput

0.580

High

554495

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

2

Small-scale

0.578

High

554411

AKT1
RAC-alpha serine/threonine-protein kinase

1

2

Small-scale

0.569

High

177185

HDAC3
Histone deacetylase 3

1

15

Small-scale

0.561

High

554409

PML
Protein PML

1

7

Small-scale

0.561

High

554422

HDAC4
Histone deacetylase 4

1

20

Small-scale

0.561

High

554532

HDAC5
Histone deacetylase 5

1

20

Small-scale

0.561

High

275171

GRAP2
GRB2-related adapter protein 2

1

1

High-throughput

0.560

High

280346

GLRX3
Glutaredoxin-3

1

1

High-throughput

0.560

High

554443

TRAF1
TNF receptor-associated factor 1

1

1

High-throughput

0.560

High

554496

RBPMS
RNA-binding protein with multiple splicing

1

1

High-throughput

0.560

High

554511

KR411
Keratin-associated protein 4-11

2

7

High-throughput

0.553

High

554512

KRA45
Keratin-associated protein 4-5

2

7

High-throughput

0.553

High

554503

HEXI2
Protein HEXIM2

1

0

High-throughput

0.549

High

554415

CASP3
Caspase-3

1

0

Small-scale

0.545

High

171516

ZBT22
Zinc finger and BTB domain-containing protein 22

1

7

High-throughput

0.541

High

554444

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

2

High-throughput

0.541

High

554449

TRI29
Tripartite motif-containing protein 29

1

1

High-throughput

0.541

High

554450

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

1

High-throughput

0.541

High

554468

RAI1
Retinoic acid-induced protein 1

1

7

High-throughput

0.541

High

174352

FANCG
Fanconi anemia group G protein

1

0

High-throughput

0.536

High

554414

BCL6
B-cell lymphoma 6 protein

1

0

High-throughput

0.536

High

554489

PSMF1
Proteasome inhibitor PI31 subunit

1

0

High-throughput

0.536

High

554504

PP16B
Protein phosphatase 1 regulatory inhibitor subunit 16B

1

0

High-throughput

0.536

High

225342

MED14
Mediator of RNA polymerase II transcription subunit 14

1

6

Small-scale

0.536

High

554421

HSP72
Heat shock-related 70 kDa protein 2

1

2

High-throughput

0.536

High

554508

HEMGN
Hemogen

1

0

Small-scale

0.529

High

554484

RIN3
Ras and Rab interactor 3

2

4

High-throughput

0.526

High

554506

LZTS2
Leucine zipper putative tumor suppressor 2

1

10

High-throughput

0.523

High

554510

KRA92
Keratin-associated protein 9-2

1

6

High-throughput

0.523

High

554513

KRA32
Keratin-associated protein 3-2

1

1

High-throughput

0.523

High

158085

TX1B3
Tax1-binding protein 3

1

0

High-throughput

0.518

High

554453

TAF7
Transcription initiation factor TFIID subunit 7

1

0

High-throughput

0.518

High

554476

ZZZ3
ZZ-type zinc finger-containing protein 3

1

0

High-throughput

0.518

High

554456

CEBPE
CCAAT/enhancer-binding protein epsilon

1

4

Small-scale

0.515

High

554473

FOG1
Zinc finger protein ZFPM1

1

11

Small-scale

0.515

High

157863

KLF11
Krueppel-like factor 11

1

15

High-throughput

0.515

High

281532

WFS1
Wolframin

1

1

High-throughput

0.515

High

358707

CRYAA
Alpha-crystallin A chain

1

3

High-throughput

0.515

High

554404

FGFR3
Fibroblast growth factor receptor 3

1

2

High-throughput

0.515

High

554416

BAG6
Large proline-rich protein BAG6

1

8

High-throughput

0.515

High

554470

Q86V38
Atrophin 1

1

7

High-throughput

0.515

High

554493

KLK6
Kallikrein-6

1

1

High-throughput

0.515

High

554534

RNF11
RING finger protein 11

1

1

High-throughput

0.515

High

554525

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

Small-scale

0.513

High

554439

GOGA2
Golgin subfamily A member 2

1

1

High-throughput

0.512

High

554459

MK06
Mitogen-activated protein kinase 6

1

7

High-throughput

0.508

High

146154

ARI1A
AT-rich interactive domain-containing protein 1A

1

15

Small-scale

0.501

High

434924

SP1
Transcription factor Sp1

1

11

Small-scale

0.501

High

554420

SMCA4
Transcription activator BRG1

1

20

Small-scale

0.501

High

554429

SPIB
Transcription factor Spi-B

1

15

Small-scale

0.501

High

554483

SMRC2
SWI/SNF complex subunit SMARCC2

1

20

Small-scale

0.501

High

554492

CBP
CREB-binding protein

1

20

Small-scale

0.501

High

554494

SMRC1
SWI/SNF complex subunit SMARCC1

1

19

Small-scale

0.501

High

554497

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

12

Small-scale

0.501

High

554530

DNM3L
DNA

1

2

Small-scale

0.501

High

499512

CH60
60 kDa heat shock protein, mitochondrial

1

3

High-throughput

0.500

High

554405

CCNC
Cyclin-C

1

1

Small-scale

0.500

High

554413

LONM
Lon protease homolog, mitochondrial

1

2

High-throughput

0.500

High

554446

MED21
Mediator of RNA polymerase II transcription subunit 21

1

1

Small-scale

0.500

High

554533

MED16
Mediator of RNA polymerase II transcription subunit 16

1

2

Small-scale

0.500

High

554471

ZDH17
Palmitoyltransferase ZDHHC17

1

4

High-throughput

0.494

High

554469

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.493

High

554519

SRA1
Steroid receptor RNA activator 1

1

0

Small-scale

0.480

High

48611

MED19
Mediator of RNA polymerase II transcription subunit 19

1

0

Small-scale

0.479

High

554425

PSME3
Proteasome activator complex subunit 3

1

0

High-throughput

0.479

High

554517

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

Small-scale

0.479

High

131690

BCL9
B-cell CLL/lymphoma 9 protein

1

15

High-throughput

0.479

High

152586

KMT2D
Histone-lysine N-methyltransferase 2D

1

16

High-throughput

0.479

High

164181

ZN609
Zinc finger protein 609

1

6

High-throughput

0.479

High

172352

NKRF
NF-kappa-B-repressing factor

1

1

High-throughput

0.479

High

183061

KDM6A
Lysine-specific demethylase 6A

1

7

High-throughput

0.479

High

215578

AKAP8
A-kinase anchor protein 8

1

2

High-throughput

0.479

High

245558

TBL1X
F-box-like/WD repeat-containing protein TBL1X

1

9

High-throughput

0.479

High

263502

PR40A
Pre-mRNA-processing factor 40 homolog A

1

4

High-throughput

0.479

High

300397

PCF11
Pre-mRNA cleavage complex 2 protein Pcf11

1

3

High-throughput

0.479

High

317810

CPSF4
Cleavage and polyadenylation specificity factor subunit 4

1

1

High-throughput

0.479

High

414156

RB
Retinoblastoma-associated protein

1

1

Small-scale

0.479

High

554412

HSP74
Heat shock 70 kDa protein 4

1

3

Small-scale

0.479

High

554418

CEBPA
CCAAT/enhancer-binding protein alpha

1

4

High-throughput

0.479

High

554419

SMCA2
Probable global transcription activator SNF2L2

1

20

High-throughput

0.479

High

554430

MECOM
Histone-lysine N-methyltransferase MECOM

1

2

High-throughput

0.479

High

554431

TLE1
Transducin-like enhancer protein 1

1

20

High-throughput

0.479

High

554432

TLE3
Transducin-like enhancer protein 3

1

17

High-throughput

0.479

High

554433

CSTF1
Cleavage stimulation factor subunit 1

1

13

High-throughput

0.479

High

554434

ZBT16
Zinc finger and BTB domain-containing protein 16

1

1

Small-scale

0.479

High

554435

RING1
E3 ubiquitin-protein ligase RING1

1

18

High-throughput

0.479

High

554436

ZO1
Tight junction protein ZO-1

1

3

Small-scale

0.479

High

554437

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

2

High-throughput

0.479

High

554445

IKZF1
DNA-binding protein Ikaros

1

1

Small-scale

0.479

High

554447

HDAC1
Histone deacetylase 1

1

15

Small-scale

0.479

High

554452

ZN638
Zinc finger protein 638

1

4

High-throughput

0.479

High

554461

RBM20
RNA-binding protein 20

1

4

High-throughput

0.479

High

554462

BEND3
BEN domain-containing protein 3

1

3

High-throughput

0.479

High

554466

BCOR
BCL-6 corepressor

1

3

High-throughput

0.479

High

554467

PAXI1
PAX-interacting protein 1

1

7

High-throughput

0.479

High

554472

SUGP2
SURP and G-patch domain-containing protein 2

1

2

High-throughput

0.479

High

554474

CCAR1
Cell division cycle and apoptosis regulator protein 1

1

1

High-throughput

0.479

High

554475

RAVR1
Ribonucleoprotein PTB-binding 1

1

4

High-throughput

0.479

High

554479

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

3

High-throughput

0.479

High

554481

ARI1B
AT-rich interactive domain-containing protein 1B

1

20

High-throughput

0.479

High

554482

KDM2B
Lysine-specific demethylase 2B

1

2

High-throughput

0.479

High

554485

MORC4
MORC family CW-type zinc finger protein 4

1

2

High-throughput

0.479

High

554490

DPF1
Zinc finger protein neuro-d4

1

20

High-throughput

0.479

High

554491

REQU
Zinc finger protein ubi-d4

1

20

High-throughput

0.479

High

554498

FUBP1
Far upstream element-binding protein 1

1

6

High-throughput

0.479

High

554500

FUBP3
Far upstream element-binding protein 3

1

6

High-throughput

0.479

High

554502

ZFR
Zinc finger RNA-binding protein

1

3

High-throughput

0.479

High

554507

PCGF1
Polycomb group RING finger protein 1

1

16

High-throughput

0.479

High

554520

HM20A
High mobility group protein 20A

1

19

High-throughput

0.479

High

554521

BRD7
Bromodomain-containing protein 7

1

18

High-throughput

0.479

High

554524

RBM12
RNA-binding protein 12

1

5

High-throughput

0.479

High

554528

CPSF2
Cleavage and polyadenylation specificity factor subunit 2

1

1

High-throughput

0.479

High

554529

RCOR3
REST corepressor 3

1

20

High-throughput

0.479

High

554531

SATB2
DNA-binding protein SATB2

1

4

High-throughput

0.479

High

554535

NCOR2
Nuclear receptor corepressor 2

1

18

High-throughput

0.479

High

103697

G5E9A7
DM1 locus, WD repeat containing

1

11

High-throughput

0.470

High

554408

GRN
Progranulin

1

1

High-throughput

0.470

High

554423

KR105
Keratin-associated protein 10-5

1

5

High-throughput

0.470

High

344787

TIMP1
Metalloproteinase inhibitor 1

1

0

Small-scale

0.458

High

475311

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

Small-scale

0.458

High

521208

SKI
Ski oncogene

1

0

Small-scale

0.458

High

548855

NDKA
Nucleoside diphosphate kinase A

1

0

Small-scale

0.458

High

554406

PSA4
Proteasome subunit alpha type-4

1

0

High-throughput

0.458

High

554463

ZN318
Zinc finger protein 318

1

0

High-throughput

0.458

High

554523

MBIP1
MAP3K12-binding inhibitory protein 1

1

0

High-throughput

0.458

High

554527

SENP1
Sentrin-specific protease 1

1

0

Small-scale

0.458

High

243877

BRD4
Bromodomain-containing protein 4

1

9

High-throughput

0.445

High

131302

CLD5
Claudin-5

1

1

Small-scale

0.437

High

554451

GSE1
Genetic suppressor element 1

1

2

High-throughput

0.437

High

554458

OCLN
Occludin

1

1

Small-scale

0.437

High

554518

FBRS
Probable fibrosin-1

1

3

High-throughput

0.437

High

207294

FRS3
Fibroblast growth factor receptor substrate 3

3

0

High-throughput

0.352

High

554478

CCD24
Coiled-coil domain-containing protein 24

3

0

High-throughput

0.352

High

554442

MKRN3
Probable E3 ubiquitin-protein ligase makorin-3

2

0

High-throughput

0.316

High

554515

CHRD
Chordin

2

0

High-throughput

0.316

High

554516

ARMC7
Armadillo repeat-containing protein 7

2

0

High-throughput

0.316

High

554486

FBF1
Fas-binding factor 1

1

0

High-throughput

0.299

High

554501

RADIL
Ras-associating and dilute domain-containing protein

1

0

High-throughput

0.299

High

554426

VA0D1
V-type proton ATPase subunit d 1

1

0

High-throughput

0.292

High

554480

PNMA1
Paraneoplastic antigen Ma1

1

0

High-throughput

0.292

High

231445

KIF1B
Kinesin-like protein KIF1B

1

0

High-throughput

0.268

Low

413820

GELS
Gelsolin

1

0

High-throughput

0.268

Low

554410

METK2
S-adenosylmethionine synthase isoform type-2

1

0

High-throughput

0.268

Low

554424

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.268

Low

554536

Q9Y649
GW128

1

0

High-throughput

0.268

Low

554460

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.251

Low

353042

IL2RA
Interleukin-2 receptor subunit alpha

1

0

Small-scale

0.249

Low

532888

PRG2
Bone marrow proteoglycan

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024