Protein: LSM1
Sm-like protein LSm1 (SPB8 protein)

Gene: LSM1
Organism: Saccharomyces cerevisiae S288C
Interactions: 132
UniProt ID: P47017

Gene Ontology (top 5):
GO:0000288 - nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000339 - RNA cap binding
GO:0000932 - P-body
GO:0003682 - chromatin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

635880

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

18

10

Small-scale

0.987

High

768230

LSM5
U6 snRNA-associated Sm-like protein LSm5

15

15

Small-scale

0.984

High

746307

LSM2
U6 snRNA-associated Sm-like protein LSm2

14

20

Small-scale

0.983

High

810530

LSM3
U6 snRNA-associated Sm-like protein LSm3

15

20

Small-scale

0.983

High

810539

LSM6
U6 snRNA-associated Sm-like protein LSm6

12

20

Small-scale

0.980

High

767790

LSM4
U6 snRNA-associated Sm-like protein LSm4

11

20

Small-scale

0.979

High

810527

LSM7
U6 snRNA-associated Sm-like protein LSm7

10

20

Small-scale

0.974

High

761974

DHH1
ATP-dependent RNA helicase DHH1

6

9

Small-scale

0.732

High

605080

XRN1
5'-3' exoribonuclease 1

6

4

Small-scale

0.729

High

810521

DCP2
m7GpppN-mRNA hydrolase

4

2

Small-scale

0.694

High

675753

RENT1
ATP-dependent helicase NAM7

3

8

Small-scale

0.662

High

731738

SN114
Pre-mRNA-splicing factor SNU114

1

16

High-throughput

0.656

High

810515

LSM8
U6 snRNA-associated Sm-like protein LSm8

1

18

Small-scale

0.656

High

810526

RIA1
Ribosome assembly protein 1

1

16

High-throughput

0.656

High

546192

SYKC
Lysine--tRNA ligase, cytoplasmic

2

1

High-throughput

0.621

High

810514

LSM1
Sm-like protein LSm1

1

18

Small-scale

0.621

High

368185

EF1A
Elongation factor 1-alpha

1

2

Small-scale

0.618

High

425031

DHE4
NADP-specific glutamate dehydrogenase 1

2

1

High-throughput

0.603

High

810554

DCP1
mRNA-decapping enzyme subunit 1

2

3

Small-scale

0.601

High

494315

HSP72
Heat shock protein SSA2

2

8

High-throughput

0.552

High

676165

XPO1
Exportin-1

1

4

High-throughput

0.536

High

766461

EDC3
Enhancer of mRNA-decapping protein 3

1

2

High-throughput

0.515

High

618335

STE11
Serine/threonine-protein kinase STE11

1

1

High-throughput

0.508

High

679867

FUN30
ATP-dependent helicase FUN30

1

2

High-throughput

0.508

High

693657

SIP1
SNF1 protein kinase subunit beta-1

1

1

High-throughput

0.508

High

698552

SLX5
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5

1

1

High-throughput

0.508

High

744964

CHK1
Serine/threonine-protein kinase CHK1

1

1

High-throughput

0.508

High

810516

MTR3
Exosome complex component MTR3

1

1

High-throughput

0.508

High

810517

BRO1
Vacuolar-sorting protein BRO1

1

1

High-throughput

0.508

High

608795

KCC2
Calcium/calmodulin-dependent protein kinase II

1

1

High-throughput

0.501

High

648202

KCC1
Calcium/calmodulin-dependent protein kinase I

1

1

High-throughput

0.501

High

715942

UTP20
U3 small nucleolar RNA-associated protein 20

1

0

High-throughput

0.493

High

452110

SWI1
SWI/SNF chromatin-remodeling complex subunit SWI1

1

0

High-throughput

0.486

High

748321

SDS24
Protein SDS24

1

0

High-throughput

0.486

High

765451

MIG3
Transcription corepressor MIG3

1

0

High-throughput

0.486

High

785004

YRB1
Ran-specific GTPase-activating protein 1

1

0

High-throughput

0.486

High

810529

SIW14
Inositol phosphatase SIW14

1

0

High-throughput

0.486

High

810534

UFO1
Ubiquitin ligase complex F-box protein UFO1

1

0

High-throughput

0.486

High

810537

DCE
Glutamate decarboxylase

1

0

High-throughput

0.486

High

810543

CMS1
Protein CMS1

1

0

High-throughput

0.486

High

810549

INP53
Polyphosphatidylinositol phosphatase INP53

1

0

High-throughput

0.486

High

810551

PTPA2
Serine/threonine-protein phosphatase 2A activator 2

1

0

High-throughput

0.486

High

696514

TOR2
Serine/threonine-protein kinase TOR2

1

2

High-throughput

0.481

High

715213

TOR1
Serine/threonine-protein kinase TOR1

1

2

High-throughput

0.481

High

376834

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

7

Small-scale

0.479

High

408399

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

1

High-throughput

0.479

High

416016

DED1
ATP-dependent RNA helicase DED1

1

5

Small-scale

0.479

High

424882

IF4E
Eukaryotic translation initiation factor 4E

1

3

Small-scale

0.479

High

543993

HSC82
ATP-dependent molecular chaperone HSC82

1

4

High-throughput

0.479

High

548415

MS116
ATP-dependent RNA helicase MSS116, mitochondrial

1

5

High-throughput

0.479

High

662624

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

692027

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

2

High-throughput

0.479

High

705357

HSP78
Heat shock protein 78, mitochondrial

1

3

High-throughput

0.479

High

764983

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

4

Small-scale

0.479

High

765135

IF4F2
Eukaryotic initiation factor 4F subunit p130

1

4

Small-scale

0.479

High

810520

EIF2A
Eukaryotic translation initiation factor 2A

1

3

High-throughput

0.479

High

810531

NOP3
Serine/arginine

1

9

Small-scale

0.479

High

810540

MHR1
Large ribosomal subunit protein mL67

1

2

High-throughput

0.479

High

810542

VAM6
Vacuolar morphogenesis protein 6

1

4

High-throughput

0.479

High

810547

SCC1
Sister chromatid cohesion protein 1

1

1

High-throughput

0.479

High

810553

RM23
Large ribosomal subunit protein uL13m

1

3

High-throughput

0.479

High

539998

EI2BA
Translation initiation factor eIF2B subunit alpha

1

1

High-throughput

0.464

High

629811

SYNM
Asparagine--tRNA ligase, mitochondrial

1

2

High-throughput

0.464

High

692828

SPT16
FACT complex subunit SPT16

1

1

High-throughput

0.464

High

775143

PDK1
[Pyruvate dehydrogenase

1

2

High-throughput

0.464

High

498675

RT01
Small ribosomal subunit protein mS43

1

0

High-throughput

0.458

High

585334

MYO2
Myosin-2

1

0

Small-scale

0.458

High

810519

MNP1
Large ribosomal subunit protein bL12m

1

0

High-throughput

0.458

High

810535

RM34
Large ribosomal subunit protein bL34m

1

0

High-throughput

0.458

High

810544

ESA1
Histone acetyltransferase ESA1

1

0

Small-scale

0.458

High

810546

NMD4
Nonsense-mediated decay protein 4

1

0

Small-scale

0.458

High

491669

HSP71
Heat shock protein SSA1

1

8

High-throughput

0.445

High

511826

SSB1
Ribosome-associated molecular chaperone SSB1

1

6

High-throughput

0.445

High

692313

PRP19
Pre-mRNA-processing factor 19

1

15

Small-scale

0.445

High

694988

HSP7F
Heat shock protein homolog SSE1

1

11

High-throughput

0.445

High

520533

RM02
Large ribosomal subunit protein bL27m

1

2

High-throughput

0.437

High

534490

RM31
Large ribosomal subunit protein mL60

1

2

High-throughput

0.437

High

589386

RM33
Large ribosomal subunit protein uL30m

1

2

High-throughput

0.437

High

607423

RM08
Large ribosomal subunit protein bL17m

1

2

High-throughput

0.437

High

607492

RM20
Large ribosomal subunit protein mL58

1

2

High-throughput

0.437

High

615613

RM25
Large ribosomal subunit protein mL59

1

2

High-throughput

0.437

High

629862

RM32
Large ribosomal subunit protein bL32m

1

1

High-throughput

0.437

High

635375

IMG1
Large ribosomal subunit protein bL19m

1

2

High-throughput

0.437

High

635785

IMG2
Large ribosomal subunit protein mL49

1

2

High-throughput

0.437

High

679566

RM09
Large ribosomal subunit protein uL3m

1

3

High-throughput

0.437

High

689515

RM41
Large ribosomal subunit protein uL23m

1

2

High-throughput

0.437

High

696875

RML2
Large ribosomal subunit protein uL2m

1

2

High-throughput

0.437

High

729804

RM38
Large ribosomal subunit protein uL14m

1

2

High-throughput

0.437

High

735148

RM03
Large ribosomal subunit protein mL44

1

2

High-throughput

0.437

High

735218

RM04
Large ribosomal subunit protein uL29m

1

1

High-throughput

0.437

High

735280

RM07
Large ribosomal subunit protein uL5m

1

2

High-throughput

0.437

High

735341

RM10
Large ribosomal subunit protein uL15m

1

2

High-throughput

0.437

High

735516

RM24
Large ribosomal subunit protein bL28m

1

2

High-throughput

0.437

High

735562

RM27
Large ribosomal subunit protein mL41

1

2

High-throughput

0.437

High

735609

RM28
Large ribosomal subunit protein mL40

1

2

High-throughput

0.437

High

735671

RM17
Large ribosomal subunit protein mL46

1

2

High-throughput

0.437

High

735728

RM36
Large ribosomal subunit protein bL31m

1

1

High-throughput

0.437

High

735795

RM39
Large ribosomal subunit protein bL33m

1

2

High-throughput

0.437

High

735830

RM40
Large ribosomal subunit protein uL24m

1

2

High-throughput

0.437

High

743353

RM16
Large ribosomal subunit protein uL16m

1

2

High-throughput

0.437

High

762339

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

777358

RN49
Large ribosomal subunit protein bL21m

1

2

High-throughput

0.437

High

810518

RL4P
Large ribosomal subunit protein uL4m

1

2

High-throughput

0.437

High

810522

RM50
Large ribosomal subunit protein bL9m

1

2

High-throughput

0.437

High

810525

RM22
Large ribosomal subunit protein uL22m

1

2

High-throughput

0.437

High

810532

RM13
Large ribosomal subunit protein mL50

1

2

High-throughput

0.437

High

810536

RM01
Large ribosomal subunit protein uL1m

1

2

High-throughput

0.437

High

810541

RM35
Large ribosomal subunit protein mL38

1

2

High-throughput

0.437

High

760759

TCPG
T-complex protein 1 subunit gamma

1

1

High-throughput

0.407

High

754137

CIC1
Proteasome-interacting protein CIC1

1

0

High-throughput

0.269

Low

387992

ADT1
ADP,ATP carrier protein 1

1

0

High-throughput

0.265

Low

448506

PRTB
Cerevisin

1

0

High-throughput

0.265

Low

700243

PMP1
Plasma membrane ATPase proteolipid 1

1

0

High-throughput

0.265

Low

775111

ATC7
Phospholipid-transporting ATPase NEO1

1

0

High-throughput

0.265

Low

809820

PMT4
Dolichyl-phosphate-mannose--protein mannosyltransferase 4

1

0

High-throughput

0.265

Low

810545

GNT1
Glucose N-acetyltransferase 1

1

0

High-throughput

0.265

Low

810548

MDM32
Mitochondrial distribution and morphology protein 32

1

0

High-throughput

0.265

Low

810552

AIR2
Protein AIR2

1

0

High-throughput

0.265

Low

480752

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

689588

RM49
Large ribosomal subunit protein mL61

1

0

High-throughput

0.249

Low

700279

RM06
Large ribosomal subunit protein uL6m

1

0

High-throughput

0.249

Low

735398

RM11
Large ribosomal subunit protein uL10m

1

0

High-throughput

0.249

Low

735457

RM15
Large ribosomal subunit protein mL57

1

0

High-throughput

0.249

Low

735768

RM37
Large ribosomal subunit protein mL54

1

0

High-throughput

0.249

Low

767318

MRX1
MIOREX complex component 1

1

0

High-throughput

0.249

Low

810524

RM19
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.249

Low

810528

RN35
Large ribosomal subunit protein bL35m

1

0

High-throughput

0.249

Low

810533

ATP25
ATPase synthesis protein 25, mitochondrial

1

0

High-throughput

0.249

Low

810538

RM51
Large ribosomal subunit protein mL43

1

0

High-throughput

0.249

Low

810550

UTP23
rRNA-processing protein UTP23

1

0

High-throughput

0.249

Low

810523

YN16
Putative uncharacterized protein YNL276C

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024