HitPredict

Interactor 1: GBB1 (P62871)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: GNB1

Interactor 2: GNAI1 (P63097)
Guanine nucleotide-binding protein G(i) subunit alpha-1 (EC 3.6.5.-) (Adenylate cyclase-inhibiting G alpha protein)
Gene: GNAI1

Species: Bos taurus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	20018744
Identification Methods	nuclear magnetic resonance
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003924 - GTPase activity GO:0005737 - cytoplasm GO:0005834 - heterotrimeric G-protein complex GO:0007186 - G protein-coupled receptor signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 340 Bt			1 354
+	Hs
		984060 GBB2_HUMAN (1-340): 5.18e-107: 318: 90.29		GNAI1_HUMAN (1-354): 0: 516: 100.00
+	Hs
		983444 GBB1_HUMAN (1-340): 1.7e-106: 316: 100.00		GNAI1_HUMAN (1-354): 0: 516: 100.00
+	Hs
		989876 GBB4_HUMAN (1-340): 2.62e-106: 316: 90.88		GNAI1_HUMAN (1-354): 0: 516: 100.00
+	Hs
		475940 GBB2_HUMAN (1-340): 5.18e-107: 318: 90.29		GNAI3_HUMAN (1-354): 0: 507: 93.79
+	Hs
		475939 GBB1_HUMAN (1-340): 1.7e-106: 316: 100.00		GNAI3_HUMAN (1-354): 0: 507: 93.79
+	Hs
		476036 GBB4_HUMAN (1-340): 2.62e-106: 316: 90.88		GNAI3_HUMAN (1-354): 0: 507: 93.79
+	Hs
		418642 GBB2_HUMAN (1-340): 5.18e-107: 318: 90.29		GNAI2_HUMAN (1-354): 2.64e-179: 502: 87.89
+	Hs
		418641 GBB1_HUMAN (1-340): 1.7e-106: 316: 100.00		GNAI2_HUMAN (1-354): 2.64e-179: 502: 87.89
+	Hs
		418741 GBB4_HUMAN (1-340): 2.62e-106: 316: 90.88		GNAI2_HUMAN (1-354): 2.64e-179: 502: 87.89
+	Hs
		482600 GBB1_HUMAN (1-340): 1.7e-106: 316: 100.00		GNAO_HUMAN (1-354): 1.39e-175: 493: 72.11
+	Ce
		604385 GBB1_CAEEL (1-340): 2.21e-107: 318: 85.88		GNAO_CAEEL (1-354): 6.14e-172: 484: 69.86
+	Mm
		617634 GBB1_MOUSE (1-340): 1.7e-106: 316: 100.00		GNAO_MOUSE (1-354): 5.01e-173: 486: 71.83
+	Bt
		415093 GBB1_BOVIN (1-340): 1.7e-106: 316: 100.00		GNAT1_BOVIN (1-354): 4.13e-169: 476: 67.80
+	Hs
		893477 GBB1_HUMAN (1-340): 1.7e-106: 316: 100.00		GNAQ_HUMAN (1-353): 3.05e-167: 472: 52.26
+	Hs
		716015 GBB1_HUMAN (1-340): 1.7e-106: 316: 100.00		GNA11_HUMAN (1-353): 1.37e-162: 460: 51.13
+	Hs
		984112 GBB2_HUMAN (1-340): 5.18e-107: 318: 90.29		GNA13_HUMAN (2-353): 2.27e-155: 442: 39.17
+	Hs
		983481 GBB1_HUMAN (1-340): 1.7e-106: 316: 100.00		GNA13_HUMAN (2-353): 2.27e-155: 442: 39.17
+	Hs
		984059 GBB2_HUMAN (1-340): 5.18e-107: 318: 90.29		GNAS2_HUMAN (1-354): 4.73e-143: 412: 38.23
+	Hs
		983443 GBB1_HUMAN (1-340): 1.7e-106: 316: 100.00		GNAS2_HUMAN (1-354): 4.73e-143: 412: 38.23
+	Hs
		989795 GBB4_HUMAN (1-340): 2.62e-106: 316: 90.88		GNAS2_HUMAN (1-354): 4.73e-143: 412: 38.23