Interactor 1: MAD1 (Q05195)
Max dimerization protein 1 (Max dimerizer 1) (Protein MAD)
Gene: MXD1

Interactor 2: SIN3A (Q96ST3)
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)
Gene: SIN3A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.752

The method score is based on:

Property Details
Experiments 26186194, 28514442, 29028833, 7889570, 33961781, 15235594, 11106735, 20547842
Identification Methods affinity chromatography technology, pull down, x-ray crystallography, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 221
Hs

1 1273
+ Mm
+ Hs
+ Mm
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Mm
+ Ce
+ Dm
+ Hs
+ Rn
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024