Protein: NU116
Nucleoporin NUP116/NSP116 (Nuclear pore protein NUP116/NSP116)

Gene: NU116, NUP116
Organism: Saccharomyces cerevisiae S288C
Interactions: 133
UniProt ID: Q02630

Gene Ontology (top 5):
GO:0000055 - ribosomal large subunit export from nucleus
GO:0000973 - post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
GO:0003723 - RNA binding
GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

971867

NU100
Nucleoporin NUP100/NSP100

7

19

Small-scale

0.965

High

830674

NU145
Nucleoporin NUP145

5

19

Small-scale

0.912

High

971888

NU116
Nucleoporin NUP116/NSP116

4

19

Small-scale

0.896

High

772783

NUP82
Nucleoporin NUP82

15

7

Small-scale

0.762

High

767629

GLE2
mRNA export factor GLE2

11

19

Small-scale

0.759

High

971907

IMB1
Importin subunit beta-1

11

20

Small-scale

0.756

High

971930

MEX67
mRNA export factor MEX67

9

17

Small-scale

0.751

High

774368

NU159
Nucleoporin NUP159

8

19

Small-scale

0.745

High

805090

NUP85
Nucleoporin NUP85

7

8

Small-scale

0.742

High

541912

NSP1
Nucleoporin NSP1

7

20

Small-scale

0.741

High

857039

NUP84
Nucleoporin NUP84

7

14

Small-scale

0.738

High

745832

NU170
Nucleoporin NUP170

5

20

Small-scale

0.704

High

811042

NU192
Nucleoporin NUP192

5

15

Small-scale

0.703

High

734036

NU133
Nucleoporin NUP133

5

11

Small-scale

0.702

High

854933

NU188
Nucleoporin NUP188

5

7

Small-scale

0.700

High

971923

CEX1
Cytoplasmic export protein 1

3

3

Small-scale

0.689

High

709345

NIC96
Nucleoporin NIC96

4

15

Small-scale

0.680

High

728208

NU120
Nucleoporin NUP120

4

7

Small-scale

0.680

High

858397

SEH1
Nucleoporin SEH1

4

20

Small-scale

0.680

High

687987

IMB3
Importin subunit beta-3

4

20

Small-scale

0.680

High

710718

MTR2
mRNA transport regulator MTR2

4

5

Small-scale

0.676

High

971897

ARX1
Probable metalloprotease ARX1

3

6

Small-scale

0.658

High

822991

NUP57
Nucleoporin NUP57

3

19

Small-scale

0.658

High

830646

NUP42
Nucleoporin NUP42

3

19

Small-scale

0.641

High

969353

NUP49
Nucleoporin NUP49/NSP49

3

19

Small-scale

0.641

High

767713

IMB4
Importin subunit beta-4

3

20

Small-scale

0.633

High

857420

MSN5
Protein MSN5

2

20

Small-scale

0.608

High

494753

HSP72
Heat shock protein SSA2

3

16

Small-scale

0.603

High

676301

XPO1
Exportin-1

2

20

High-throughput

0.600

High

971903

SEC13
Protein transport protein SEC13

2

20

Small-scale

0.595

High

767597

NU157
Nucleoporin NUP157

2

20

Small-scale

0.585

High

971906

NUP59
Nucleoporin ASM4

2

12

Small-scale

0.585

High

971911

BUD20
Bud site selection protein 20

2

2

Small-scale

0.585

High

746534

IMB2
Importin subunit beta-2

2

20

Small-scale

0.584

High

805121

SAC3
Nuclear mRNA export protein SAC3

2

5

Small-scale

0.584

High

970946

MLP1
Protein MLP1

2

20

High-throughput

0.584

High

595060

NUP1
Nucleoporin NUP1

2

20

Small-scale

0.571

High

691658

NUP2
Nucleoporin NUP2

2

20

Small-scale

0.571

High

697596

KA122
Importin beta-like protein KAP122

2

1

Small-scale

0.571

High

763304

PO152
Nucleoporin POM152

2

7

Small-scale

0.571

High

763519

NUP60
Nucleoporin NUP60

2

4

Small-scale

0.571

High

971889

IMA1
Importin subunit alpha

2

20

Small-scale

0.571

High

971891

KA120
Importin beta-like protein KAP120

2

20

Small-scale

0.571

High

971896

NUP53
Nucleoporin NUP53

2

12

Small-scale

0.571

High

971920

GLE1
mRNA export factor GLE1

2

12

Small-scale

0.571

High

698182

AFG2
ATPase family gene 2 protein

2

5

Small-scale

0.561

High

515007

RNA1
Ran GTPase-activating protein 1

1

4

Small-scale

0.561

High

675773

RENT1
ATP-dependent helicase NAM7

1

2

Small-scale

0.552

High

746030

ATG8
Autophagy-related protein 8

2

13

Small-scale

0.533

High

971925

RTP1
RNA polymerase II assembly factor RTP1

1

1

Small-scale

0.527

High

971893

RMT2
Protein arginine N-methyltransferase 2

2

3

Small-scale

0.526

High

971900

RRP17
Ribosomal RNA-processing protein 17

2

1

Small-scale

0.521

High

763705

MBO1
Gamma tubulin complex adapter SPC72

2

1

High-throughput

0.513

High

492177

HSP71
Heat shock protein SSA1

1

16

Small-scale

0.501

High

971926

RRP12
Ribosomal RNA-processing protein 12

1

2

Small-scale

0.501

High

587881

AP1
AP-1-like transcription factor YAP1

1

1

High-throughput

0.494

High

624273

AP2
AP-1-like transcription factor YAP2

1

1

High-throughput

0.494

High

971909

PEX19
Peroxisomal membrane protein import receptor PEX19

1

1

High-throughput

0.494

High

624712

CG22
G2/mitotic-specific cyclin-2

1

6

High-throughput

0.489

High

624749

CG23
G2/mitotic-specific cyclin-3

1

6

High-throughput

0.489

High

715379

SPT7
Transcriptional activator SPT7

1

10

High-throughput

0.489

High

837454

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

3

High-throughput

0.489

High

971894

GCN5
Histone acetyltransferase GCN5

1

8

High-throughput

0.489

High

692063

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

7

High-throughput

0.479

High

754069

BRL1
Nucleus export protein BRL1

1

4

Small-scale

0.479

High

773978

MLP2
Protein MLP2

1

20

High-throughput

0.479

High

971892

HEH2
Inner nuclear membrane protein HEH2

1

4

Small-scale

0.479

High

971901

SXM1
Importin beta SMX1

1

20

High-throughput

0.479

High

971917

MDN1
Midasin

1

1

Small-scale

0.479

High

971927

MTR10
mRNA transport regulator MTR10

1

20

High-throughput

0.479

High

971931

HRP1
Nuclear polyadenylated RNA-binding protein 4

1

6

High-throughput

0.479

High

767355

SERA
D-3-phosphoglycerate dehydrogenase 1

1

1

High-throughput

0.464

High

858519

TEL2
Telomere length regulation protein TEL2

1

1

High-throughput

0.464

High

861014

UTP8
U3 small nucleolar RNA-associated protein 8

1

0

Small-scale

0.458

High

971912

NOP8
60S ribosome subunit biogenesis protein NOP8

1

0

High-throughput

0.458

High

965470

NOP3
Serine/arginine

1

6

Small-scale

0.457

High

416806

CDC31
Cell division control protein 31

1

3

Small-scale

0.445

High

691712

NDC1
Nucleoporin NDC1

1

4

Small-scale

0.445

High

766344

SNU13
13 kDa ribonucleoprotein-associated protein

1

1

Small-scale

0.445

High

766685

NUG1
Nuclear GTP-binding protein NUG1

1

1

Small-scale

0.445

High

775017

YRB2
Ran-specific GTPase-activating protein 2

1

20

Small-scale

0.445

High

864669

NOG2
Nucleolar GTP-binding protein 2

1

1

Small-scale

0.445

High

971890

NOG1
Nucleolar GTP-binding protein 1

1

3

Small-scale

0.445

High

971895

HAS1
ATP-dependent RNA helicase HAS1

1

1

Small-scale

0.445

High

971922

POM34
Nucleoporin POM34

1

5

Small-scale

0.445

High

376905

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

4

High-throughput

0.437

High

546779

SEC23
Protein transport protein SEC23

1

5

High-throughput

0.437

High

628383

SIS1
Protein SIS1

1

3

High-throughput

0.437

High

663084

TF2B
Transcription initiation factor IIB

1

5

High-throughput

0.437

High

680943

HS104
Heat shock protein 104

1

3

High-throughput

0.437

High

694196

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

6

High-throughput

0.437

High

701550

SC61A
Protein transport protein SEC61

1

3

High-throughput

0.437

High

810635

MDV1
Mitochondrial division protein 1

1

7

Small-scale

0.437

High

837414

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

10

High-throughput

0.437

High

860441

RSC1
Chromatin structure-remodeling complex subunit RSC1

1

12

High-throughput

0.437

High

860942

SHY1
Cytochrome oxidase assembly protein SHY1

1

1

Small-scale

0.437

High

866788

SAM50
Sorting assembly machinery 50 kDa subunit

1

2

High-throughput

0.437

High

971898

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

1

High-throughput

0.437

High

971905

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

2

High-throughput

0.437

High

971919

SCC1
Sister chromatid cohesion protein 1

1

1

High-throughput

0.437

High

634739

KRR1
KRR1 small subunit processome component

1

0

Small-scale

0.426

High

754174

CIC1
Proteasome-interacting protein CIC1

1

0

Small-scale

0.426

High

860863

PESC
Pescadillo homolog

1

0

Small-scale

0.426

High

971918

NOP53
Ribosome biogenesis protein NOP53

1

0

Small-scale

0.426

High

971929

PNO1
Pre-rRNA-processing protein PNO1

1

0

Small-scale

0.426

High

512412

SSB1
Ribosome-associated molecular chaperone SSB1

1

14

High-throughput

0.407

High

695340

HSP7F
Heat shock protein homolog SSE1

1

19

High-throughput

0.407

High

769238

SSB2
Ribosome-associated molecular chaperone SSB2

1

14

High-throughput

0.407

High

953681

CTR9
RNA polymerase-associated protein CTR9

1

2

Small-scale

0.407

High

971902

RRB1
Ribosome assembly protein RRB1

1

3

Small-scale

0.407

High

971914

BMS1
Ribosome biogenesis protein BMS1

1

2

Small-scale

0.407

High

799889

SPO74
Sporulation-specific protein 74

2

0

High-throughput

0.323

High

971904

IVY1
Protein IVY1

2

0

High-throughput

0.323

High

709381

LTV1
Protein LTV1

1

0

High-throughput

0.282

High

747666

YBY7
UPF0303 protein YBR137W

1

0

High-throughput

0.282

High

812562

SGM1
Protein SGM1

1

0

High-throughput

0.282

High

866380

NIS1
Protein NIS1

1

0

High-throughput

0.282

High

971916

YO289
Uncharacterized protein YOR289W

1

0

High-throughput

0.282

High

971924

DCP1
mRNA-decapping enzyme subunit 1

1

0

High-throughput

0.282

High

971921

RTN2
Reticulon-like protein 2

1

0

High-throughput

0.238

Low

746595

OLA1
Obg-like ATPase 1

1

0

Small-scale

0.232

Low

748179

AIM4
Altered inheritance of mitochondria protein 4

1

0

Small-scale

0.232

Low

755980

YHS7
Uncharacterized protein YHR127W

1

0

Small-scale

0.232

Low

764229

NOC2
Nucleolar complex protein 2

1

0

Small-scale

0.232

Low

767138

TPA1
Prolyl 3,4-dihydroxylase TPA1

1

0

Small-scale

0.232

Low

768037

NSA2
Ribosome biogenesis protein NSA2

1

0

Small-scale

0.232

Low

971899

RUVB1
RuvB-like protein 1

1

0

Small-scale

0.232

Low

971908

NOC4
Nucleolar complex protein 4

1

0

Small-scale

0.232

Low

971910

EXP1
ER export of PMA1 protein 1

1

0

Small-scale

0.232

Low

971913

ETT1
Enhancer of translation termination 1

1

0

Small-scale

0.232

Low

971915

TMA46
Translation machinery-associated protein 46

1

0

Small-scale

0.232

Low

971928

NOP14
Nucleolar complex protein 14

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024