Protein: UBR1
E3 ubiquitin-protein ligase UBR1 (EC 2.3.2.27) (N-end-recognizing protein) (N-recognin-1) (RING-type E3 ubiquitin transferase UBR1)

Gene: UBR1
Organism: Saccharomyces cerevisiae S288C
Interactions: 56
UniProt ID: P19812

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0005737 - cytoplasm
GO:0006513 - protein monoubiquitination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

410209

UBC2
Ubiquitin-conjugating enzyme E2 2

15

14

Small-scale

0.763

High

587313

CUP9
Homeobox protein CUP9

5

1

Small-scale

0.655

High

587286

UBR1
E3 ubiquitin-protein ligase UBR1

1

2

Small-scale

0.647

High

490293

HSP71
Heat shock protein SSA1

3

2

Small-scale

0.624

High

587301

UFD4
Ubiquitin fusion degradation protein 4

2

0

Small-scale

0.606

High

587288

MCK1
Protein kinase MCK1

1

2

Small-scale

0.598

High

587321

PRS8
26S proteasome regulatory subunit 8 homolog

1

1

Small-scale

0.578

High

587302

PRS7
26S proteasome regulatory subunit 7 homolog

1

1

Small-scale

0.561

High

587324

VAM6
Vacuolar morphogenesis protein 6

2

0

Small-scale

0.559

High

587290

SIS1
Protein SIS1

2

0

Small-scale

0.547

High

587298

RPN2
26S proteasome regulatory subunit RPN2

1

0

Small-scale

0.537

High

587307

CHK1
Serine/threonine-protein kinase CHK1

1

0

Small-scale

0.520

High

539221

YAK1
Dual specificity protein kinase YAK1

1

0

High-throughput

0.513

High

587287

PP11
Serine/threonine-protein phosphatase PP1-1

1

0

High-throughput

0.513

High

587296

CCR4
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4

1

0

High-throughput

0.513

High

587310

PEX7
Peroxisomal targeting signal 2 receptor

1

0

High-throughput

0.513

High

477116

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

2

Small-scale

0.501

High

587305

SPT7
Transcriptional activator SPT7

1

1

High-throughput

0.489

High

561826

ATE1
Arginyl-tRNA--protein transferase 1

1

1

Small-scale

0.481

High

587308

6PGD1
6-phosphogluconate dehydrogenase, decarboxylating 1

1

0

Small-scale

0.480

High

587300

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

430808

DYR
Dihydrofolate reductase

1

0

Small-scale

0.458

High

587294

RENT1
ATP-dependent helicase NAM7

1

0

Small-scale

0.458

High

587297

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

587304

PMT1
Dolichyl-phosphate-mannose--protein mannosyltransferase 1

1

0

Small-scale

0.458

High

587309

NMD2
Nonsense-mediated mRNA decay protein 2

1

0

Small-scale

0.458

High

587315

YJO4
Uncharacterized protein YJL144W

1

0

Small-scale

0.458

High

587318

CDH1
APC/C activator protein CDH1

1

0

Small-scale

0.458

High

587319

HST2
NAD-dependent protein deacetylase HST2

1

0

High-throughput

0.458

High

587320

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

587323

AVO2
Target of rapamycin complex 2 subunit AVO2

1

0

Small-scale

0.458

High

510215

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

587299

HSP7F
Heat shock protein homolog SSE1

1

4

High-throughput

0.445

High

587311

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

523337

SRS2
ATP-dependent DNA helicase SRS2

1

1

Small-scale

0.439

High

587292

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

477883

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.426

High

587314

TCPH
T-complex protein 1 subunit eta

1

0

High-throughput

0.426

High

587316

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

0

High-throughput

0.426

High

587322

ADA2
Transcriptional adapter 2

1

0

High-throughput

0.426

High

381592

GAL80
Galactose/lactose metabolism regulatory protein GAL80

1

0

Small-scale

0.391

High

587291

MGMT
Methylated-DNA--protein-cysteine methyltransferase

3

0

Small-scale

0.349

High

587325

SCC1
Sister chromatid cohesion protein 1

2

0

Small-scale

0.310

High

587306

CENPA
Histone H3-like centromeric protein CSE4

2

0

Small-scale

0.305

High

587317

YGI1
Uncharacterized protein YGL081W

1

0

High-throughput

0.279

Low

587289

KC11
Casein kinase I homolog 1

1

0

Small-scale

0.269

Low

587312

PSA4
Proteasome subunit alpha type-4

1

0

Small-scale

0.269

Low

587295

RAD16
DNA repair protein RAD16

1

0

Small-scale

0.251

Low

522405

STE6
Alpha-factor-transporting ATPase

1

0

Small-scale

0.249

Low

566123

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.249

Low

580510

FAS2
Fatty acid synthase subunit alpha

1

0

Small-scale

0.249

Low

587303

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

587326

NDOR1
NADPH-dependent diflavin oxidoreductase 1

1

0

Small-scale

0.249

Low

587327

SMC6
Structural maintenance of chromosomes protein 6

1

0

High-throughput

0.249

Low

587293

PSB5
Proteasome subunit beta type-5

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024