Protein: CDK6
Cyclin-dependent kinase 6 (EC 2.7.11.22) (CR2 protein kinase) (CRK2) (Cell division protein kinase 6) (Serine/threonine-protein kinase PLSTIRE)

Gene: CDK6
Organism: Mus musculus
Interactions: 14
UniProt ID: Q64261

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0001726 - ruffle
GO:0001954 - positive regulation of cell-matrix adhesion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

629215

CCND1
G1/S-specific cyclin-D1

3

20

Small-scale

0.817

High

673186

CCND3
G1/S-specific cyclin-D3

3

20

Small-scale

0.817

High

673123

CCND2
G1/S-specific cyclin-D2

2

20

Small-scale

0.759

High

763419

CDN1A
Cyclin-dependent kinase inhibitor 1

1

20

Small-scale

0.618

High

803847

CDN1B
Cyclin-dependent kinase inhibitor 1B

1

20

Small-scale

0.618

High

1141372

CDN2D
Cyclin-dependent kinase 4 inhibitor D

1

17

Small-scale

0.618

High

956230

DAB1
Disabled homolog 1

1

6

Small-scale

0.561

High

404145

JUN
Transcription factor Jun

1

2

Small-scale

0.536

High

786543

STAT3
Signal transducer and activator of transcription 3

1

1

Small-scale

0.536

High

527159

RB
Retinoblastoma-associated protein

1

20

Small-scale

0.501

High

794650

H11
Histone H1.1

1

20

Small-scale

0.501

High

970144

CTNB1
Catenin beta-1

1

8

Small-scale

0.479

High

1112968

Q3UM65
Runt-related transcription factor

1

3

Small-scale

0.479

High

1145125

FOXP3
Forkhead box protein P3

1

7

High-throughput

0.479

High


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Last updated: 15 Jul 2024