Protein: CLH
Clathrin heavy chain

Gene: CLH, Chc
Organism: Drosophila melanogaster
Interactions: 144
UniProt ID: P29742

Gene Ontology (top 5):
GO:0005198 - structural molecule activity
GO:0005802 - trans-Golgi network
GO:0005886 - plasma membrane
GO:0005905 - clathrin-coated pit
GO:0005938 - cell cortex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

715171

CLC
Clathrin light chain

2

7

High-throughput

0.737

High

597824

BICD
Protein bicaudal D

2

4

Small-scale

0.644

High

715186

Q9W329
Golgi-localized, gamma-adaptin ear containing, ARF binding protein

1

20

Small-scale

0.618

High

197046

O18332
FI01544p

2

2

High-throughput

0.571

High

564951

ATNA
Sodium/potassium-transporting ATPase subunit alpha

2

3

High-throughput

0.571

High

715078

COPB
Coatomer subunit beta

2

7

High-throughput

0.571

High

715094

VATA2
V-type proton ATPase catalytic subunit A isoform 2

2

2

High-throughput

0.571

High

715103

Q7K3J0
T-complex protein 1 subunit theta

2

1

High-throughput

0.571

High

715120

Q8T8W3
AT21416p

2

7

High-throughput

0.571

High

715144

Q9VAY2
Heat shock protein 83

2

3

High-throughput

0.571

High

715152

ARL8
ADP-ribosylation factor-like protein 8

2

4

High-throughput

0.571

High

715175

Q9VWL0
Mec2

2

3

High-throughput

0.571

High

715162

GOLP3
Golgi phosphoprotein 3 homolog sauron

2

0

Small-scale

0.559

High

715087

ROP
Protein ROP

2

0

High-throughput

0.547

High

715076

RAC1
Ras-related protein Rac1

1

8

High-throughput

0.541

High

715129

HRS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

17

High-throughput

0.541

High

198025

PRS8
26S proteasome regulatory subunit 8

2

3

High-throughput

0.521

High

652003

ATC1
Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type

2

3

High-throughput

0.521

High

715074

2AAA
Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit

2

1

High-throughput

0.521

High

715080

PRS4
26S proteasome regulatory subunit 4

2

4

High-throughput

0.521

High

715081

TCPG
T-complex protein 1 subunit gamma

2

2

High-throughput

0.521

High

715106

Q7KMQ0
26S proteasome regulatory subunit 7

2

3

High-throughput

0.521

High

715125

LDH
L-lactate dehydrogenase

2

2

High-throughput

0.521

High

715133

Q9V3V6
26S proteasome regulatory complex subunit p50

2

6

High-throughput

0.521

High

715136

Q9V455
Importin subunit alpha

2

1

High-throughput

0.521

High

715150

IPO9
Importin-9

2

1

High-throughput

0.521

High

715151

Q9VHL2
T-complex protein 1 subunit eta

2

1

High-throughput

0.521

High

715155

Q9VK69
T-complex protein 1 subunit delta

2

2

High-throughput

0.521

High

715160

Q9VN44
FI07923p

2

3

High-throughput

0.521

High

715163

Q9VQL1
serine--tRNA ligase

2

1

High-throughput

0.521

High

715173

IDH3A
Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

2

1

High-throughput

0.521

High

715187

Q9W392
T-complex protein 1 subunit beta

2

2

High-throughput

0.521

High

602962

KINH
Kinesin heavy chain

1

0

Small-scale

0.513

High

118280

M9ND00
Dynamin associated protein 160, isoform D

1

7

Small-scale

0.501

High

624286

CI
Transcriptional activator cubitus interruptus

1

2

High-throughput

0.494

High

715095

SO
Protein sine oculis

1

0

High-throughput

0.486

High

391880

HSP83
Heat shock protein 83

1

3

High-throughput

0.479

High

715083

ARF1
ADP-ribosylation factor 1

1

2

High-throughput

0.479

High

715090

DYL1
Dynein light chain 1, cytoplasmic

1

1

Small-scale

0.479

High

715102

Q7K3H0
LD28067p

1

6

High-throughput

0.479

High

715107

TERA
Transitional endoplasmic reticulum ATPase TER94

1

2

High-throughput

0.479

High

715111

Q7KTD0
ABC-type glutathione-S-conjugate transporter

1

3

High-throughput

0.479

High

715112

Q7KU90
Liquid facets, isoform B

1

11

Small-scale

0.479

High

715113

AKT1
RAC serine/threonine-protein kinase

1

3

High-throughput

0.479

High

715115

Q8IRH0
Puromycin-sensitive aminopeptidase

1

1

High-throughput

0.479

High

715126

FOXO
Forkhead box protein O

1

1

High-throughput

0.479

High

715131

RAB5
Ras-related protein Rab5

1

4

High-throughput

0.479

High

715176

Q9VX95
DnaJ homolog subfamily C member 22

1

1

Small-scale

0.479

High

715182

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

3

High-throughput

0.479

High

715082

CDK5
Cyclin-dependent kinase 5 homolog

1

2

High-throughput

0.464

High

715119

PUF68
Poly(U)-binding-splicing factor hfp

1

1

High-throughput

0.464

High

715146

Q9VDE3
LD08669p

1

6

High-throughput

0.464

High

715185

Q9W2E3
Negative cofactor 2alpha

1

1

High-throughput

0.464

High

561559

SPTCA
Spectrin alpha chain

1

0

High-throughput

0.458

High

715093

MERH
Moesin/ezrin/radixin homolog 2

1

0

High-throughput

0.458

High

715184

Q9W1K4
Egalitarian, isoform B

1

0

High-throughput

0.458

High

715071

VATB
V-type proton ATPase subunit B

1

3

High-throughput

0.445

High

715086

ARL2
ADP-ribosylation factor-like protein 2

1

4

High-throughput

0.445

High

715147

FLNA
Filamin-A

1

3

High-throughput

0.445

High

715154

Q9VK56
ABC-type glutathione-S-conjugate transporter

1

3

High-throughput

0.445

High

715180

Q9W0E4
Aminopeptidase

1

1

High-throughput

0.445

High

52639

A1Z729
NADP-retinol dehydrogenase

1

1

High-throughput

0.437

High

119564

M9PAY7
Pi3K21B, isoform C

1

4

High-throughput

0.437

High

704330

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

1

High-throughput

0.437

High

715073

ATPA
ATP synthase subunit alpha, mitochondrial

1

2

High-throughput

0.437

High

715099

Q76NQ0
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.437

High

715109

Q7KN97
Pyruvate carboxylase

1

2

High-throughput

0.437

High

715110

Q7KT38
non-specific serine/threonine protein kinase

1

7

Small-scale

0.437

High

715123

Q94533
Ribosomal protein S6 kinase

1

3

High-throughput

0.437

High

715148

ATD3A
ATPase family AAA domain-containing protein 3A homolog

1

6

High-throughput

0.437

High

715165

Q9VR42
Serine/threonine-protein kinase RIO3

1

2

High-throughput

0.437

High

715172

RS10B
Small ribosomal subunit protein eS10B

1

4

High-throughput

0.437

High

715174

Q9VWJ6
FI03615p

1

1

High-throughput

0.437

High

715075

SQH
Myosin regulatory light chain sqh

1

0

High-throughput

0.426

High

715114

CPLX
Complexin

1

0

High-throughput

0.426

High

715124

VDAC
Voltage-dependent anion-selective channel

1

0

High-throughput

0.426

High

657728

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

1

1

High-throughput

0.407

High

715079

ACTZ
Actin-related protein 1

1

1

High-throughput

0.407

High

715089

Q0E9E2
Pyruvate carboxylase

1

2

High-throughput

0.407

High

715097

Q6NP35
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.407

High

715104

Q7KKI0
T-complex protein 1 subunit epsilon

1

3

High-throughput

0.407

High

715118

Q8SYG3
E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.407

High

715128

Q960C7
NADP-retinol dehydrogenase

1

1

High-throughput

0.407

High

715132

JIL1
Chromosomal serine/threonine-protein kinase JIL-1

1

4

High-throughput

0.407

High

715189

Q9W414
Regulatory particle triple-A ATPase 4

1

3

High-throughput

0.407

High

715142

Q9VAN8
FI15955p1

2

0

High-throughput

0.313

High

144855

ATPG
ATP synthase subunit gamma, mitochondrial

2

0

High-throughput

0.298

High

715092

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

2

0

High-throughput

0.298

High

715098

Q6NP72
GEO09659p1

2

0

High-throughput

0.298

High

715101

Q7K110
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

2

0

High-throughput

0.298

High

715108

Q7KN94
Electron transfer flavoprotein subunit alpha

2

0

High-throughput

0.298

High

715135

KRH2
Krueppel homolog 2

2

0

High-throughput

0.298

High

715139

Q9V9Q4
LD43819p

2

0

High-throughput

0.298

High

715156

NFS1
Cysteine desulfurase, mitochondrial

2

0

High-throughput

0.298

High

715164

Q9VQL7
Fatty acid synthase

2

0

High-throughput

0.298

High

715169

Q9VV75
AT02348p

2

0

High-throughput

0.298

High

715170

Q9VW54
26S proteasome non-ATPase regulatory subunit 2

2

0

High-throughput

0.298

High

715177

Q9VXQ5
Chaperonin containing TCP1 subunit 6

2

0

High-throughput

0.298

High

715181

GALE
UDP-glucose 4-epimerase

2

0

High-throughput

0.298

High

715188

Q9W3N1
RH59310p

2

0

High-throughput

0.298

High

232099

ESS2
Splicing factor ESS-2 homolog

1

0

High-throughput

0.265

Low

620688

SXL
Protein sex-lethal

1

0

High-throughput

0.265

Low

715100

Q7JZC9
Nnf1a

1

0

High-throughput

0.265

Low

715138

Q9V4B8
RE68558p

1

0

High-throughput

0.265

Low

715159

Q9VM98
AT06841p1

1

0

High-throughput

0.265

Low

715178

BAP60
Brahma-associated protein of 60 kDa

1

0

High-throughput

0.265

Low

51892

PO210
Nuclear pore membrane glycoprotein 210

1

0

High-throughput

0.249

Low

55410

A1Z9E3
Elongation factor Tu

1

0

High-throughput

0.249

Low

68892

MBD56
Methyl-CpG-binding domain protein 5/6 homolog sba

1

0

High-throughput

0.249

Low

437974

PYR1
Multifunctional protein r

1

0

High-throughput

0.249

Low

626985

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.249

Low

715072

GLT
Glutactin

1

0

High-throughput

0.249

Low

715084

CCD1P
Probable cytochrome P450 12d1 proximal, mitochondrial

1

0

High-throughput

0.249

Low

715088

Q0E8E8
Phosphate carrier protein, mitochondrial

1

0

High-throughput

0.249

Low

715091

SIMA
Protein similar

1

0

High-throughput

0.249

Low

715121

MESD
LDLR chaperone boca

1

0

High-throughput

0.249

Low

715137

Q9V470
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

1

0

High-throughput

0.249

Low

715143

Q9VAW3
glutamine--fructose-6-phosphate transaminase

1

0

High-throughput

0.249

Low

715145

Q9VCF8
LD23561p

1

0

High-throughput

0.249

Low

715149

CYFIP
Cytoplasmic FMR1-interacting protein

1

0

Small-scale

0.249

Low

715157

Q9VLC5
aldehyde dehydrogenase

1

0

High-throughput

0.249

Low

715161

Q9VPR1
GH02075p

1

0

High-throughput

0.249

Low

715166

ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.249

Low

715179

Q9VZL3
very-long-chain enoyl-CoA reductase

1

0

High-throughput

0.249

Low

304184

ERD2
ER lumen protein-retaining receptor

1

0

High-throughput

0.232

Low

360516

COX2
Cytochrome c oxidase subunit 2

1

0

High-throughput

0.232

Low

669680

PSMD3
Probable 26S proteasome non-ATPase regulatory subunit 3

1

0

High-throughput

0.232

Low

715077

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

0

High-throughput

0.232

Low

715085

ESM3
Enhancer of split m3 protein

1

0

High-throughput

0.232

Low

715096

Q500Y7
GEO11443p1

1

0

High-throughput

0.232

Low

715105

Q7KLX3
Translocon-associated protein subunit delta

1

0

High-throughput

0.232

Low

715116

Q8MSW0
Isoleucine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.232

Low

715117

Q8STG9
DSec61alpha

1

0

High-throughput

0.232

Low

715122

DYLT
Dynein light chain Tctex-type

1

0

Small-scale

0.232

Low

715127

Q95WY3
Nucleolar protein 56

1

0

High-throughput

0.232

Low

715130

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

High-throughput

0.232

Low

715134

Q9V434
Asparagine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.232

Low

715140

FRIL
Ferritin light chain

1

0

High-throughput

0.232

Low

715141

CISD2
CDGSH iron-sulfur domain protein

1

0

High-throughput

0.232

Low

715153

Q9VJD1
Glucosidase 2 subunit beta

1

0

High-throughput

0.232

Low

715158

Q9VLS7
LD21067p

1

0

High-throughput

0.232

Low

715167

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.232

Low

715168

Q9VUZ0
Translocon-associated protein subunit beta

1

0

High-throughput

0.232

Low

715183

Q9W1H8
acetyl-CoA C-acyltransferase

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025