HitPredict - High confidence protein-protein interactions

Protein: A1AT1
Alpha-1-antitrypsin 1-1 (AAT) (Alpha-1 protease inhibitor 1) (Alpha-1-antiproteinase) (Serine protease inhibitor 1-1) (Serine protease inhibitor A1a) (Serpin A1a)

Gene: A1AT1, Serpina1a
Organism: Mus musculus
Interactions: 5
UniProt ID: P07758

Gene Ontology (top 5):
GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0006487 - protein N-linked glycosylation
GO:0006953 - acute-phase response

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
459951	ELNE Neutrophil elastase	1	20	Small-scale	0.647	High
459954	CELA1 Chymotrypsin-like elastase family member 1	1	12	Small-scale	0.647	High
459955	Q9Z1R9 trypsin	1	20	Small-scale	0.647	High
459952	FACD2 Fanconi anemia group D2 protein homolog	1	10	High-throughput	0.437	High
459953	BACD1 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1	1	0	High-throughput	0.249	Low

Service provided by Combinatics, Japan

Last updated: 11Aug2025