HitPredict

Interactor 1: A1AT1 (P07758)
Alpha-1-antitrypsin 1-1 (AAT) (Alpha-1 protease inhibitor 1) (Alpha-1-antiproteinase) (Serine protease inhibitor 1-1) (Serine protease inhibitor A1a) (Serpin A1a)
Gene: Serpina1a

Interactor 2: ELNE (Q3UP87)
Neutrophil elastase (EC 3.4.21.37) (Elastase-2) (Leukocyte elastase)
Gene: Elane

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	11961105
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Serpin~Trypsin
Common GO terms	GO:0005615 - extracellular space
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 413 Mm			1 265
+	Mm
		459955 A1AT1_MOUSE (1-413): 4.89e-180: 509: 100.00		Q9Z1R9_MOUSE (10-249): 3.16e-108: 314: 31.87
+	Hs
		369312 A1AT_HUMAN (1-413): 1.94e-176: 500: 62.77		PRTN3_HUMAN (28-247): 2.03e-99: 292: 56.50
+	Hs
		369300 A1AT_HUMAN (1-413): 1.94e-176: 500: 62.77		ELNE_HUMAN (1-264): 4.96e-93: 276: 71.32
+	Hs
		369296 A1AT_HUMAN (1-413): 1.94e-176: 500: 62.77		KLK1_HUMAN (12-250): 4.02e-92: 274: 30.57
+	Hs
		369520 AACT_HUMAN (15-410): 7.51e-167: 476: 43.21		KLK13_HUMAN (6-261): 9.92e-100: 294: 26.07
+	Hs
		369437 AACT_HUMAN (15-410): 7.51e-167: 476: 43.21		KLK2_HUMAN (7-250): 1.68e-95: 282: 27.82
+	Hs
		369427 AACT_HUMAN (15-410): 7.51e-167: 476: 43.21		ELNE_HUMAN (1-264): 4.96e-93: 276: 71.32
+	Hs
		398000 IPSP_HUMAN (46-410): 6.1e-155: 445: 42.12		KLKB1_HUMAN (19-258): 5.04e-98: 301: 27.41
+	Hs
		397992 IPSP_HUMAN (46-410): 6.1e-155: 445: 42.12		FA11_HUMAN (21-248): 2.02e-94: 292: 24.39
+	Hs
		425167 IPSP_HUMAN (46-410): 6.1e-155: 445: 42.12		KLK2_HUMAN (7-250): 1.68e-95: 282: 27.82
+	Mm
		459954 A1AT1_MOUSE (1-413): 4.89e-180: 509: 100.00		CELA1_MOUSE (23-249): 9.15e-32: 119: 33.60
+	Hs
		369301 A1AT_HUMAN (1-413): 1.94e-176: 500: 62.77		CATG_HUMAN (24-248): 1.31e-34: 126: 36.29
+	Hs
		369299 A1AT_HUMAN (1-413): 1.94e-176: 500: 62.77		CEL2A_HUMAN (23-246): 4.72e-33: 123: 35.37
+	Hs
		369329 A1AT_HUMAN (1-413): 1.94e-176: 500: 62.77		GRAM_HUMAN (15-245): 4.23e-28: 109: 32.13
+	Hs
		369297 A1AT_HUMAN (1-413): 1.94e-176: 500: 62.77		KLK3_HUMAN (21-246): 1.26e-27: 108: 32.39
+	Hs
		369428 AACT_HUMAN (15-410): 7.51e-167: 476: 43.21		CATG_HUMAN (24-248): 1.31e-34: 126: 36.29
+	Hs
		369447 AACT_HUMAN (15-410): 7.51e-167: 476: 43.21		GRAM_HUMAN (15-245): 4.23e-28: 109: 32.13
+	Hs
		518736 SPB9_HUMAN (42-410): 7.02e-160: 456: 33.16		GRAB_HUMAN (24-249): 1.39e-34: 126: 33.89
+	Hs
		895476 SPB9_HUMAN (42-410): 7.02e-160: 456: 33.16		GRAM_HUMAN (15-245): 4.23e-28: 109: 32.13
+	Hs
		425160 IPSP_HUMAN (46-410): 6.1e-155: 445: 42.12		KLK3_HUMAN (21-246): 1.26e-27: 108: 32.39