Protein: HEM3
Porphobilinogen deaminase (PBG) (EC 2.5.1.61) (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase)

Gene: HEM3
Organism: Saccharomyces cerevisiae S288C
Interactions: 9
UniProt ID: P28789

Gene Ontology (top 5):
GO:0004418 - hydroxymethylbilane synthase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006782 - protoporphyrinogen IX biosynthetic process
GO:0006783 - heme biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

488925

SWI6
Regulatory protein SWI6

1

0

High-throughput

0.458

High

705116

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

705117

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.458

High

705118

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.458

High

544063

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

705119

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

526101

HSP72
Heat shock protein SSA2

1

0

High-throughput

0.426

High

705120

YO036
Uncharacterized protein YOL036W

1

0

High-throughput

0.249

Low

705121

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025