Protein: SEC66
Translocation protein SEC66 (Protein HSS1) (Sec62/63 complex 31.5 kDa subunit)

Gene: SEC66
Organism: Saccharomyces cerevisiae S288C
Interactions: 58
UniProt ID: P33754

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0030447 - filamentous growth
GO:0030867 - rough endoplasmic reticulum membrane
GO:0031204 - post-translational protein targeting to membrane, translocation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

701356

SC61A
Protein transport protein SEC61

5

1

Small-scale

0.917

High

541663

SEC63
Protein translocation protein SEC63

14

0

Small-scale

0.727

High

707199

SEC72
Translocation protein SEC72

8

0

Small-scale

0.717

High

601686

SEC62
Translocation protein SEC62

5

0

Small-scale

0.684

High

707192

SSH1
Sec sixty-one protein homolog

1

1

Small-scale

0.647

High

707185

PMT1
Dolichyl-phosphate-mannose--protein mannosyltransferase 1

2

2

High-throughput

0.601

High

707187

YET1
Endoplasmic reticulum transmembrane protein 1

2

1

Small-scale

0.584

High

707186

SC61G
Protein transport protein SSS1

2

0

Small-scale

0.547

High

707209

SC6B1
Protein transport protein SBH1

1

0

Small-scale

0.546

High

707203

ALG5
Dolichyl-phosphate beta-glucosyltransferase

1

0

High-throughput

0.518

High

707205

GPI2
Phosphatidylinositol N-acetylglucosaminyltransferase GPI2 subunit

1

0

High-throughput

0.518

High

592865

SRP54
Signal recognition particle subunit SRP54

1

0

Small-scale

0.480

High

520243

HMDH1
3-hydroxy-3-methylglutaryl-coenzyme A reductase 1

1

1

High-throughput

0.479

High

520324

HMDH2
3-hydroxy-3-methylglutaryl-coenzyme A reductase 2

1

1

High-throughput

0.479

High

679892

PMT2
Dolichyl-phosphate-mannose--protein mannosyltransferase 2

1

2

High-throughput

0.479

High

707198

HPH2
Protein HPH2

1

1

Small-scale

0.479

High

707206

PMT4
Dolichyl-phosphate-mannose--protein mannosyltransferase 4

1

2

High-throughput

0.479

High

707212

TMEDA
Endoplasmic reticulum vesicle protein 25

1

1

High-throughput

0.479

High

707218

ERP1
Protein ERP1

1

1

High-throughput

0.479

High

707219

YET3
Endoplasmic reticulum transmembrane protein 3

1

1

High-throughput

0.479

High

707221

HPH1
Protein HPH1

1

1

Small-scale

0.479

High

474108

MPH3
Alpha-glucosides permease MPH3

1

0

High-throughput

0.460

High

707207

STE24
CAAX prenyl protease 1

1

0

Small-scale

0.460

High

560625

BIP
Endoplasmic reticulum chaperone BiP

1

0

Small-scale

0.458

High

596963

ACO1
Acyl-CoA desaturase 1

1

0

High-throughput

0.458

High

629463

ERG4
Delta(24(24(1)))-sterol reductase ERG4

1

0

High-throughput

0.458

High

634068

RER1
Protein RER1

1

0

Small-scale

0.458

High

634309

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.458

High

635189

CWH43
Protein CWH43

1

0

High-throughput

0.458

High

704614

PLSC
1-acyl-sn-glycerol-3-phosphate acyltransferase

1

0

High-throughput

0.458

High

707184

OSTB
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1

1

0

High-throughput

0.458

High

707188

MCD4
GPI ethanolamine phosphate transferase 1

1

0

High-throughput

0.458

High

707189

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

0

High-throughput

0.458

High

707190

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.458

High

707191

MKAR
Very-long-chain 3-oxoacyl-CoA reductase

1

0

High-throughput

0.458

High

707193

LAG1
Ceramide synthase LAG1

1

0

High-throughput

0.458

High

707195

NSG1
Protein NSG1

1

0

High-throughput

0.458

High

707197

STT3
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3

1

0

High-throughput

0.458

High

707200

SPF1
Endoplasmic reticulum transmembrane helix translocase

1

0

High-throughput

0.458

High

707202

ELO3
Fatty acid elongase 3

1

0

High-throughput

0.458

High

707204

ALG2
Alpha-1,3/1,6-mannosyltransferase ALG2

1

0

High-throughput

0.458

High

707208

HLJ1
Protein HLJ1

1

0

High-throughput

0.458

High

707210

ALG9
Alpha-1,2-mannosyltransferase ALG9

1

0

High-throughput

0.458

High

707214

OSTD
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1

1

0

High-throughput

0.458

High

707216

CUE4
CUE domain-containing protein CUE4

1

0

High-throughput

0.458

High

707217

SPC2
Signal peptidase complex subunit 2

1

0

High-throughput

0.458

High

707220

PGA3
Plasma membrane-associated coenzyme Q6 reductase PGA3

1

0

High-throughput

0.458

High

707213

SED5
Integral membrane protein SED5

1

0

Small-scale

0.426

High

707194

YHE2
Putative uncharacterized protein YHL042W

1

0

High-throughput

0.282

High

707201

PIC2
Mitochondrial phosphate carrier protein 2

1

0

High-throughput

0.282

High

707196

TEM1
Protein TEM1

1

0

High-throughput

0.265

Low

667809

SEC65
Signal recognition particle subunit SEC65

1

0

Small-scale

0.261

Low

543483

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.249

Low

661802

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

707215

TOM1
E3 ubiquitin-protein ligase TOM1

1

0

High-throughput

0.249

Low

630698

PRTD
Saccharolysin

1

0

High-throughput

0.238

Low

510787

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.232

Low

707211

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024