Protein: SMD1
Small nuclear ribonucleoprotein Sm D1 (Sm-D1) (snRNP core protein D1)

Gene: SMD1
Organism: Saccharomyces cerevisiae S288C
Interactions: 98
UniProt ID: Q02260

Gene Ontology (top 5):
GO:0000243 - commitment complex
GO:0000245 - spliceosomal complex assembly
GO:0000387 - spliceosomal snRNP assembly
GO:0000395 - mRNA 5'-splice site recognition
GO:0000398 - mRNA splicing, via spliceosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

766943

RSMB
Small nuclear ribonucleoprotein-associated protein B

7

4

Small-scale

0.960

High

970249

RU2A
U2 small nuclear ribonucleoprotein A'

6

3

Small-scale

0.943

High

795410

SMD3
Small nuclear ribonucleoprotein Sm D3

5

7

Small-scale

0.922

High

731758

SN114
Pre-mRNA-splicing factor SNU114

4

2

High-throughput

0.896

High

586513

PRP9
Pre-mRNA-splicing factor PRP9

4

1

High-throughput

0.892

High

704703

PRP8
Pre-mRNA-splicing factor 8

4

1

Small-scale

0.892

High

770324

RUXG
Small nuclear ribonucleoprotein G

4

9

High-throughput

0.881

High

970241

SMD2
Small nuclear ribonucleoprotein Sm D2

3

2

High-throughput

0.839

High

811663

LSM8
U6 snRNA-associated Sm-like protein LSm8

3

11

High-throughput

0.830

High

962581

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

3

2

Small-scale

0.827

High

970239

RU1C
U1 small nuclear ribonucleoprotein C

3

0

High-throughput

0.811

High

970247

LUC7
Protein LUC7

3

0

High-throughput

0.796

High

970231

PRP3
U4/U6 small nuclear ribonucleoprotein PRP3

2

1

High-throughput

0.789

High

710743

LOT5
Protein LOT5

3

0

Small-scale

0.782

High

746337

LSM2
U6 snRNA-associated Sm-like protein LSm2

2

7

High-throughput

0.776

High

873654

RUXF
Small nuclear ribonucleoprotein F

2

2

High-throughput

0.776

High

970253

RUXE
Small nuclear ribonucleoprotein E

2

1

High-throughput

0.776

High

697246

BRR2
Pre-mRNA-splicing helicase BRR2

7

5

Small-scale

0.741

High

767821

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

4

High-throughput

0.691

High

703259

PRP40
Pre-mRNA-processing protein PRP40

4

1

High-throughput

0.691

High

970233

CEF1
Pre-mRNA-splicing factor CEF1

4

2

Small-scale

0.686

High

696661

RU1A
U1 small nuclear ribonucleoprotein A

5

0

Small-scale

0.684

High

970250

CWC2
Pre-mRNA-splicing factor CWC2

3

2

High-throughput

0.667

High

860152

SNU71
U1 small nuclear ribonucleoprotein component SNU71

4

0

Small-scale

0.664

High

970236

SNU56
56 kDa U1 small nuclear ribonucleoprotein component

4

0

High-throughput

0.664

High

586435

PRP6
Pre-mRNA-splicing factor 6

3

3

High-throughput

0.662

High

692418

PRP21
Pre-mRNA-splicing factor PRP21

3

1

High-throughput

0.662

High

763246

PRP39
Pre-mRNA-processing factor 39

3

4

High-throughput

0.662

High

830821

PRP31
Pre-mRNA-processing factor 31

3

1

High-throughput

0.662

High

710202

NCBP1
Nuclear cap-binding protein complex subunit 1

4

0

High-throughput

0.661

High

692341

PRP19
Pre-mRNA-processing factor 19

3

3

Small-scale

0.650

High

970228

CUS1
Cold sensitive U2 snRNA suppressor 1

3

1

High-throughput

0.650

High

970257

BRR1
Pre-mRNA-splicing factor BRR1

1

0

High-throughput

0.631

High

884821

LSM3
U6 snRNA-associated Sm-like protein LSm3

1

12

High-throughput

0.618

High

960463

NAM8
Protein NAM8

3

0

Small-scale

0.613

High

970245

PRP11
Pre-mRNA-splicing factor PRP11

2

1

High-throughput

0.601

High

970227

SMD1
Small nuclear ribonucleoprotein Sm D1

1

0

Small-scale

0.586

High

970237

SYF1
Pre-mRNA-splicing factor SYF1

2

3

Small-scale

0.584

High

970252

CLF1
Pre-mRNA-splicing factor CLF1

2

3

Small-scale

0.584

High

970232

CWC21
Pre-mRNA-splicing factor CWC21

2

0

Small-scale

0.559

High

970248

NCBP2
Nuclear cap-binding protein subunit 2

2

0

High-throughput

0.559

High

970255

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

2

0

Small-scale

0.559

High

688725

AAR2
A1 cistron-splicing factor AAR2

1

1

High-throughput

0.515

High

705928

XPOT
Exportin-T

1

1

High-throughput

0.508

High

622333

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22

1

1

Small-scale

0.501

High

866351

CARME
Carnosine N-methyltransferase

1

0

High-throughput

0.493

High

811768

RAV1
Regulator of V-ATPase in vacuolar membrane protein 1

1

0

High-throughput

0.486

High

858982

ARO8
Aromatic/aminoadipate aminotransferase 1

1

0

High-throughput

0.486

High

970230

SLU7
Pre-mRNA-splicing factor SLU7

1

0

High-throughput

0.486

High

544271

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.479

High

589094

PRP4
U4/U6 small nuclear ribonucleoprotein PRP4

1

2

High-throughput

0.479

High

598579

PRP5
Pre-mRNA-processing ATP-dependent RNA helicase PRP5

1

2

High-throughput

0.479

High

638835

SPB4
ATP-dependent rRNA helicase SPB4

1

2

High-throughput

0.479

High

694195

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

1

High-throughput

0.479

High

778628

PRP17
Pre-mRNA-processing factor 17

1

4

High-throughput

0.479

High

836925

SF3B1
U2 snRNP component HSH155

1

2

High-throughput

0.479

High

970235

PRP42
U1 small nuclear ribonucleoprotein component PRP42

1

6

High-throughput

0.479

High

970238

RSE1
Pre-mRNA-splicing factor RSE1

1

1

High-throughput

0.479

High

970254

PRP46
Pre-mRNA-splicing factor PRP46

1

3

High-throughput

0.479

High

970229

ULP1
Ubiquitin-like-specific protease 1

1

0

High-throughput

0.460

High

566217

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.458

High

598639

ISY1
Pre-mRNA-splicing factor ISY1

1

0

High-throughput

0.458

High

629387

BUD31
Pre-mRNA-splicing factor BUD31

1

0

High-throughput

0.458

High

655738

PRP45
Pre-mRNA-processing protein 45

1

0

High-throughput

0.458

High

657757

YJU2
Splicing factor YJU2

1

0

High-throughput

0.458

High

663075

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

692060

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

0

High-throughput

0.458

High

732385

MUD2
Splicing factor MUD2

1

0

Small-scale

0.458

High

733088

NTR2
Pre-mRNA-splicing factor NTR2

1

0

High-throughput

0.458

High

746868

SLT11
Pre-mRNA-splicing factor SLT11

1

0

High-throughput

0.458

High

747719

SP381
Pre-mRNA-splicing factor SPP381

1

0

High-throughput

0.458

High

748080

NTC20
Pre-mRNA-splicing factor NTC20

1

0

High-throughput

0.458

High

762483

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

860350

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.458

High

861067

SYF2
Pre-mRNA-splicing factor SYF2

1

0

High-throughput

0.458

High

861571

CWC22
Pre-mRNA-splicing factor CWC22

1

0

High-throughput

0.458

High

961600

PRP38
Pre-mRNA-splicing factor 38

1

0

High-throughput

0.458

High

970234

CWC15
Pre-mRNA-splicing factor CWC15

1

0

High-throughput

0.458

High

970240

SN309
Pre-mRNA-splicing factor SNT309

1

0

High-throughput

0.458

High

970243

DIB1
Spliceosomal protein DIB1

1

0

High-throughput

0.458

High

970244

RDS3
Pre-mRNA-splicing factor RDS3

1

0

High-throughput

0.458

High

970246

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

970251

BBP
Branchpoint-bridging protein

1

0

Small-scale

0.458

High

492168

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

494744

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

512399

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

766164

HSP7E
Heat shock protein SSC3, mitochondrial

1

1

High-throughput

0.445

High

769229

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

737203

LONM
Lon protease homolog, mitochondrial

1

1

High-throughput

0.437

High

773976

MLP2
Protein MLP2

1

1

High-throughput

0.437

High

865367

CWC25
Pre-mRNA-splicing factor CWC25

1

0

High-throughput

0.426

High

865481

JJJ1
J protein JJJ1

1

0

High-throughput

0.426

High

970242

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.426

High

565231

SAC7
GTPase-activating protein SAC7

1

0

High-throughput

0.265

Low

710686

PXA2
Peroxisomal long-chain fatty acid import protein 1

1

0

High-throughput

0.265

Low

746664

QDR3
Quinidine resistance protein 3

1

0

High-throughput

0.265

Low

970256

SEC39
Protein transport protein SEC39

1

0

High-throughput

0.265

Low


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Last updated: 15 Jul 2024