Protein: ITPR2
Inositol 1,4,5-trisphosphate receptor type 2 (IP3 receptor isoform 2) (IP3R 2) (InsP3R2) (Type 2 inositol 1,4,5-trisphosphate receptor) (Type 2 InsP3 receptor)

Gene: ITPR2
Organism: Homo sapiens
Interactions: 112
UniProt ID: Q14571

Gene Ontology (top 5):
GO:0001666 - response to hypoxia
GO:0005220 - inositol 1,4,5-trisphosphate-gated calcium channel activity
GO:0005509 - calcium ion binding
GO:0005654 - nucleoplasm
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1055720

TRPC4
Short transient receptor potential channel 4

1

14

Small-scale

0.713

High

361217

TNNC2
Troponin C, skeletal muscle

1

7

High-throughput

0.691

High

1055676

ITPR3
Inositol 1,4,5-trisphosphate receptor type 3

1

14

High-throughput

0.691

High

1055685

RASEF
Ras and EF-hand domain-containing protein

1

2

High-throughput

0.691

High

1055712

CABP2
Calcium-binding protein 2

1

10

High-throughput

0.691

High

58349

TESP1
Protein TESPA1

3

2

High-throughput

0.667

High

1055706

P2Y12
P2Y purinoceptor 12

3

3

High-throughput

0.667

High

1055727

CCG2
Voltage-dependent calcium channel gamma-2 subunit

3

0

High-throughput

0.638

High

160923

RAB7L
Ras-related protein Rab-7L1

2

6

High-throughput

0.628

High

686994

ACHA3
Neuronal acetylcholine receptor subunit alpha-3

2

1

High-throughput

0.628

High

1055690

ZNRF4
E3 ubiquitin-protein ligase ZNRF4

2

1

High-throughput

0.628

High

1055693

LMBL2
Lethal(3)malignant brain tumor-like protein 2

2

1

High-throughput

0.628

High

1052969

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

11

High-throughput

0.618

High

278695

BODG
Gamma-butyrobetaine dioxygenase

3

2

High-throughput

0.609

High

716577

CAH8
Carbonic anhydrase-related protein

3

2

High-throughput

0.609

High

1055710

IPPK
Inositol-pentakisphosphate 2-kinase

2

0

High-throughput

0.602

High

1039061

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

2

11

High-throughput

0.601

High

1055691

LPAR1
Lysophosphatidic acid receptor 1

2

0

High-throughput

0.585

High

390229

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

2

2

High-throughput

0.584

High

1055713

ANLN
Anillin

2

2

High-throughput

0.584

High

1055721

ZRAN1
Ubiquitin thioesterase ZRANB1

2

1

High-throughput

0.584

High

979905

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

2

0

High-throughput

0.576

High

484125

CALM3
Calmodulin-3

1

4

High-throughput

0.575

High

1055698

TAFA4
Chemokine-like protein TAFA-4

2

2

High-throughput

0.574

High

1055679

RN123
E3 ubiquitin-protein ligase RNF123

1

9

High-throughput

0.553

High

1055681

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.553

High

234216

PEPL
Periplakin

1

10

High-throughput

0.536

High

600762

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

2

High-throughput

0.536

High

717822

BMI1
Polycomb complex protein BMI-1

1

2

High-throughput

0.536

High

724829

MYH9
Myosin-9

1

6

High-throughput

0.536

High

813027

CAZA2
F-actin-capping protein subunit alpha-2

1

2

High-throughput

0.536

High

849666

CCR6
C-C chemokine receptor type 6

1

2

High-throughput

0.536

High

984583

CALD1
Caldesmon

1

13

High-throughput

0.536

High

1030928

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

3

High-throughput

0.536

High

1038869

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

1

11

High-throughput

0.536

High

1038963

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

1

11

High-throughput

0.536

High

1055678

TTMP
TPA-induced transmembrane protein

1

1

High-throughput

0.536

High

1055696

SGF29
SAGA-associated factor 29

1

2

High-throughput

0.536

High

1055723

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

11

High-throughput

0.536

High

1055728

IRAG1
Inositol 1,4,5-triphosphate receptor associated 1

1

3

High-throughput

0.536

High

884715

NU107
Nuclear pore complex protein Nup107

1

0

High-throughput

0.513

High

1055682

TPRA1
Transmembrane protein adipocyte-associated 1

1

0

High-throughput

0.513

High

1055704

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.513

High

1055722

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

High-throughput

0.493

High

796079

MAGA9
Melanoma-associated antigen 9

1

2

High-throughput

0.489

High

163804

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

6

High-throughput

0.479

High

205393

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.479

High

227455

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

273798

NU155
Nuclear pore complex protein Nup155

1

2

High-throughput

0.479

High

308708

KI20A
Kinesin-like protein KIF20A

1

6

High-throughput

0.479

High

315188

CNEP1
CTD nuclear envelope phosphatase 1

1

3

High-throughput

0.479

High

390889

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

2

High-throughput

0.479

High

514686

CP2C9
Cytochrome P450 2C9

1

1

High-throughput

0.479

High

567057

CXA1
Gap junction alpha-1 protein

1

5

High-throughput

0.479

High

568667

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

9

High-throughput

0.479

High

572954

PRS6A
26S proteasome regulatory subunit 6A

1

6

High-throughput

0.479

High

573693

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

1

High-throughput

0.479

High

795129

SSRA
Translocon-associated protein subunit alpha

1

2

High-throughput

0.479

High

813470

CAPZB
F-actin-capping protein subunit beta

1

2

High-throughput

0.479

High

818041

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.479

High

825415

LMAN1
Protein ERGIC-53

1

1

High-throughput

0.479

High

838833

EMD
Emerin

1

2

High-throughput

0.479

High

844925

RAB7A
Ras-related protein Rab-7a

1

7

High-throughput

0.479

High

845479

RAB9A
Ras-related protein Rab-9A

1

6

High-throughput

0.479

High

847467

BAP31
B-cell receptor-associated protein 31

1

2

High-throughput

0.479

High

890148

SC61B
Protein transport protein Sec61 subunit beta

1

2

High-throughput

0.479

High

894010

CDC42
Cell division control protein 42 homolog

1

11

High-throughput

0.479

High

900470

RHOA
Transforming protein RhoA

1

12

High-throughput

0.479

High

951559

RL19
Large ribosomal subunit protein eL19

1

1

High-throughput

0.479

High

961654

REEP5
Receptor expression-enhancing protein 5

1

1

High-throughput

0.479

High

969694

KIF23
Kinesin-like protein KIF23

1

3

High-throughput

0.479

High

1055677

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.479

High

1055686

CXD3
Gap junction delta-3 protein

1

5

High-throughput

0.479

High

1055687

SIR6
NAD-dependent protein deacylase sirtuin-6

1

3

High-throughput

0.479

High

1055688

DHB11
Estradiol 17-beta-dehydrogenase 11

1

2

High-throughput

0.479

High

1055689

PDZD8
PDZ domain-containing protein 8

1

1

High-throughput

0.479

High

1055692

ESR2
Estrogen receptor beta

1

6

High-throughput

0.479

High

1055694

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

2

High-throughput

0.479

High

1055697

DNJC1
DnaJ homolog subfamily C member 1

1

9

High-throughput

0.479

High

1055699

SEC62
Translocation protein SEC62

1

2

High-throughput

0.479

High

1055701

DERL1
Derlin-1

1

2

High-throughput

0.479

High

1055702

LNP
Endoplasmic reticulum junction formation protein lunapark

1

3

High-throughput

0.479

High

1055703

CCDC8
Coiled-coil domain-containing protein 8

1

1

High-throughput

0.479

High

1055705

DJC25
DnaJ homolog subfamily C member 25

1

6

High-throughput

0.479

High

1055707

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

2

High-throughput

0.479

High

1055708

TMT1A
Thiol S-methyltransferase TMT1A

1

2

High-throughput

0.479

High

1055709

ECT2
Protein ECT2

1

1

High-throughput

0.479

High

1055711

B2L10
Bcl-2-like protein 10

1

2

Small-scale

0.479

High

1055714

PXMP2
Peroxisomal membrane protein 2

1

2

High-throughput

0.479

High

1055715

ST7
Suppressor of tumorigenicity 7 protein

1

2

High-throughput

0.479

High

1055718

ELOV5
Very long chain fatty acid elongase 5

1

2

High-throughput

0.479

High

1055719

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

2

High-throughput

0.479

High

1055724

LAMP3
Lysosome-associated membrane glycoprotein 3

1

2

High-throughput

0.479

High

1055725

DJC16
DnaJ homolog subfamily C member 16

1

4

High-throughput

0.479

High

118310

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.458

High

209989

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

319839

HERC2
E3 ubiquitin-protein ligase HERC2

1

0

High-throughput

0.458

High

668683

PML
Protein PML

1

0

High-throughput

0.458

High

790401

RL35
Large ribosomal subunit protein uL29

1

0

High-throughput

0.458

High

905635

RS7
Small ribosomal subunit protein eS7

1

0

High-throughput

0.458

High

1055717

EXOC1
Exocyst complex component 1

1

0

High-throughput

0.438

High

236928

BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

1

15

High-throughput

0.437

High

590923

BTF3
Transcription factor BTF3

1

2

High-throughput

0.437

High

914072

RB11A
Ras-related protein Rab-11A

1

1

High-throughput

0.437

High

1055680

A16L1
Autophagy-related protein 16-1

1

7

High-throughput

0.437

High

1055683

DYR2
Dihydrofolate reductase 2, mitochondrial

1

1

High-throughput

0.437

High

1055684

S15A3
Solute carrier family 15 member 3

1

1

High-throughput

0.437

High

1055695

S2546
Mitochondrial outer membrane protein SLC25A46

1

1

High-throughput

0.437

High

1055700

CNPY3
Protein canopy homolog 3

1

1

Small-scale

0.437

High

1055716

OTULL
Inactive ubiquitin thioesterase OTULINL

1

2

High-throughput

0.437

High

99600

F5H1C8
Solute carrier family 15 member 3

1

1

High-throughput

0.407

High

1055726

RT07
Small ribosomal subunit protein uS7m

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024