HitPredict - High confidence protein-protein interactions

Protein: THI6
Thiamine biosynthetic bifunctional enzyme [Includes: Thiamine-phosphate synthase (TP synthase) (TPS) (EC 2.5.1.3) (Thiamine-phosphate pyrophosphorylase) (TMP pyrophosphorylase) (TMP-PPase); Hydroxyethylthiazole kinase (EC 2.7.1.50) (4-methyl-5-beta-hydroxyethylthiazole kinase) (TH kinase) (THZ kinase)]

Gene: THI6
Organism: Saccharomyces cerevisiae S288C
Interactions: 12
UniProt ID: P41835

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004417 - hydroxyethylthiazole kinase activity
GO:0004789 - thiamine-phosphate diphosphorylase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
784707	THI6 Thiamine biosynthetic bifunctional enzyme [Includes: Thiamine-phosphate synthase	1	3	High-throughput	0.656	High
784708	ACAC Acetyl-CoA carboxylase	1	0	Small-scale	0.460	High
733445	KAE1 tRNA N6-adenosine threonylcarbamoyltransferase	1	0	High-throughput	0.458	High
784710	MLH3 DNA mismatch repair protein MLH3	1	0	High-throughput	0.458	High
784709	IMA1 Importin subunit alpha	1	1	High-throughput	0.457	High
511688	SSB1 Ribosome-associated molecular chaperone SSB1	1	1	High-throughput	0.445	High
768692	SSB2 Ribosome-associated molecular chaperone SSB2	1	1	High-throughput	0.445	High
494224	HSP72 Heat shock protein SSA2	1	0	High-throughput	0.426	High
628180	SIS1 Protein SIS1	1	0	High-throughput	0.426	High
766062	HSP7E Heat shock protein SSC3, mitochondrial	1	0	High-throughput	0.426	High
662510	TF2B Transcription initiation factor IIB	1	0	High-throughput	0.249	Low

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Last updated: 15 Jul 2024