Protein: APBP2
Amyloid protein-binding protein 2 (Amyloid beta precursor protein-binding protein 2) (APP-BP2) (Protein interacting with APP tail 1)

Gene: APBP2, APPBP2
Organism: Homo sapiens
Interactions: 203
UniProt ID: Q92624

Gene Ontology (top 5):
GO:0003777 - microtubule motor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005874 - microtubule

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

761794

HSP74
Heat shock 70 kDa protein 4

3

7

High-throughput

0.871

High

1112937

CUL2
Cullin-2

3

7

Small-scale

0.861

High

1139980

RRS1
Ribosome biogenesis regulatory protein homolog

4

1

High-throughput

0.705

High

1365951

MUL1
Mitochondrial ubiquitin ligase activator of NFKB 1

4

5

High-throughput

0.703

High

958686

CSN2
COP9 signalosome complex subunit 2

4

6

High-throughput

0.691

High

1104923

XRCC4
DNA repair protein XRCC4

4

2

High-throughput

0.691

High

1366004

CSN3
COP9 signalosome complex subunit 3

4

3

High-throughput

0.691

High

479851

GSTP1
Glutathione S-transferase P

3

2

High-throughput

0.675

High

1091784

PP1R8
Nuclear inhibitor of protein phosphatase 1

3

1

High-throughput

0.675

High

1244193

KLH35
Kelch-like protein 35

3

2

High-throughput

0.675

High

1365998

KAD3
GTP:AMP phosphotransferase AK3, mitochondrial

3

1

High-throughput

0.675

High

1366007

COR2B
Coronin-2B

3

6

High-throughput

0.675

High

1366013

SNX5
Sorting nexin-5

3

3

High-throughput

0.675

High

1292792

SKAP1
Src kinase-associated phosphoprotein 1

3

11

High-throughput

0.667

High

1365949

GLMN
Glomulin

3

1

High-throughput

0.662

High

422755

A4
Amyloid-beta precursor protein

3

5

Small-scale

0.660

High

1149828

TAF11
Transcription initiation factor TFIID subunit 11

3

0

High-throughput

0.646

High

1329260

GCSAM
Germinal center-associated signaling and motility protein

3

0

High-throughput

0.646

High

1365987

LANC2
LanC-like protein 2

3

0

High-throughput

0.646

High

1365993

LUZP4
Leucine zipper protein 4

3

0

High-throughput

0.646

High

1366003

SYNRG
Synergin gamma

3

0

High-throughput

0.646

High

1085687

TBL3
Transducin beta-like protein 3

2

4

High-throughput

0.646

High

1252042

KIF6
Kinesin-like protein KIF6

2

20

High-throughput

0.640

High

839910

AF9
Protein AF-9

3

0

High-throughput

0.639

High

1337124

HIPK4
Homeodomain-interacting protein kinase 4

2

9

High-throughput

0.633

High

553758

MYCL
Protein L-Myc

2

8

High-throughput

0.628

High

1104623

IKZF1
DNA-binding protein Ikaros

2

3

High-throughput

0.628

High

1338503

DOCK8
Dedicator of cytokinesis protein 8

2

1

High-throughput

0.628

High

1365958

THOC3
THO complex subunit 3

2

6

High-throughput

0.628

High

1366005

ZN232
Zinc finger protein 232

2

5

High-throughput

0.628

High

1366010

LC7L2
Putative RNA-binding protein Luc7-like 2

3

3

High-throughput

0.616

High

659693

NFYA
Nuclear transcription factor Y subunit alpha

2

0

High-throughput

0.613

High

320742

UBXN7
UBX domain-containing protein 7

2

1

High-throughput

0.611

High

1365974

C1QT2
Complement C1q tumor necrosis factor-related protein 2

3

1

High-throughput

0.609

High

162851

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

2

3

High-throughput

0.606

High

262551

MCE1
mRNA-capping enzyme

2

1

High-throughput

0.606

High

555732

ACTN1
Alpha-actinin-1

2

1

High-throughput

0.606

High

1153010

MYLK
Myosin light chain kinase, smooth muscle

2

4

High-throughput

0.606

High

1204202

RIPL1
RILP-like protein 1

2

9

High-throughput

0.606

High

1313092

PPIL6
Probable inactive peptidyl-prolyl cis-trans isomerase-like 6

2

1

High-throughput

0.606

High

1365976

MCLN1
Mucolipin-1

2

1

High-throughput

0.606

High

1365966

CSN8
COP9 signalosome complex subunit 8

2

0

High-throughput

0.602

High

1365983

CSN7B
COP9 signalosome complex subunit 7b

2

0

High-throughput

0.602

High

1366000

FBXL5
F-box/LRR-repeat protein 5

2

0

High-throughput

0.602

High

1094389

CSN1
COP9 signalosome complex subunit 1

2

5

High-throughput

0.601

High

1359824

RASF5
Ras association domain-containing protein 5

2

0

High-throughput

0.598

High

1365965

WDR24
GATOR2 complex protein WDR24

2

9

High-throughput

0.590

High

1196209

S22A6
Solute carrier family 22 member 6

2

1

High-throughput

0.584

High

1365969

SYT11
Synaptotagmin-11

2

1

High-throughput

0.584

High

479942

CYTT
Cystatin-SA

2

0

High-throughput

0.580

High

846645

MSH2
DNA mismatch repair protein Msh2

2

0

High-throughput

0.580

High

893018

KHK
Ketohexokinase

2

0

High-throughput

0.580

High

1196894

BCL7A
B-cell CLL/lymphoma 7 protein family member A

2

0

High-throughput

0.580

High

1280310

PLPL5
Patatin-like phospholipase domain-containing protein 5

2

0

High-throughput

0.580

High

167343

KLF11
Krueppel-like factor 11

1

6

High-throughput

0.573

High

651690

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

2

High-throughput

0.573

High

842661

WASP
Actin nucleation-promoting factor WAS

1

2

High-throughput

0.573

High

930765

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

1

1

High-throughput

0.573

High

1006929

KC1G2
Casein kinase I isoform gamma-2

1

5

High-throughput

0.573

High

1025578

CDK16
Cyclin-dependent kinase 16

1

4

High-throughput

0.573

High

1193280

LONF3
LON peptidase N-terminal domain and RING finger protein 3

1

11

High-throughput

0.573

High

1352295

RN128
E3 ubiquitin-protein ligase RNF128

1

1

High-throughput

0.573

High

1365950

RNF34
E3 ubiquitin-protein ligase RNF34

1

5

High-throughput

0.573

High

1365988

ANR10
Ankyrin repeat domain-containing protein 10

1

6

High-throughput

0.573

High

1365999

CCNL1
Cyclin-L1

1

3

High-throughput

0.573

High

1147229

ELOB
Elongin-B

2

0

Small-scale

0.559

High

296670

AL1L1
Cytosolic 10-formyltetrahydrofolate dehydrogenase

2

5

High-throughput

0.553

High

592680

ITB4
Integrin beta-4

2

3

High-throughput

0.553

High

612103

ITB5
Integrin beta-5

2

4

High-throughput

0.553

High

1048271

HGFA
Hepatocyte growth factor activator serine protease

2

4

High-throughput

0.553

High

1120602

DPYS
Dihydropyrimidinase

2

1

High-throughput

0.553

High

1147494

RHEB
GTP-binding protein Rheb

2

3

High-throughput

0.553

High

1316041

TRM2A
tRNA

2

1

High-throughput

0.553

High

1365953

RAB7B
Ras-related protein Rab-7b

2

1

High-throughput

0.553

High

1365961

WFKN1
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1

2

1

High-throughput

0.553

High

1365986

AAA1
Asc-type amino acid transporter 1

2

1

High-throughput

0.553

High

1365995

BIN2
Bridging integrator 2

2

1

High-throughput

0.553

High

596766

DPEP1
Dipeptidase 1

1

0

High-throughput

0.549

High

659816

SAHH
Adenosylhomocysteinase

1

0

High-throughput

0.549

High

1100627

DHRS2
Dehydrogenase/reductase SDR family member 2, mitochondrial

1

0

High-throughput

0.549

High

1179183

CTC1
CST complex subunit CTC1

1

0

High-throughput

0.549

High

1365959

ZC3HA
Zinc finger CCCH domain-containing protein 10

1

0

High-throughput

0.549

High

1365967

TCF25
Ribosome quality control complex subunit TCF25

1

0

High-throughput

0.549

High

230377

CREB3
Cyclic AMP-responsive element-binding protein 3

1

5

High-throughput

0.541

High

1322852

EID3
EP300-interacting inhibitor of differentiation 3

1

1

High-throughput

0.541

High

51640

CBAR1
CBY1-interacting BAR domain-containing protein 1

1

0

High-throughput

0.536

High

69811

ZN785
Zinc finger protein 785

1

2

High-throughput

0.536

High

176217

PER2
Period circadian protein homolog 2

1

4

High-throughput

0.536

High

651133

CCNO
Cyclin-O

1

2

High-throughput

0.536

High

1040871

MECOM
Histone-lysine N-methyltransferase MECOM

1

3

High-throughput

0.536

High

1122531

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

2

High-throughput

0.536

High

1199863

SETMR
Histone-lysine N-methyltransferase SETMAR

1

2

High-throughput

0.536

High

1216048

TTBK1
Tau-tubulin kinase 1

1

5

High-throughput

0.536

High

1272507

CSN6
COP9 signalosome complex subunit 6

1

3

High-throughput

0.536

High

1358810

KBTB7
Kelch repeat and BTB domain-containing protein 7

1

1

High-throughput

0.536

High

1365952

TRI52
E3 ubiquitin-protein ligase TRIM52

1

5

High-throughput

0.536

High

1365964

UBP28
Ubiquitin carboxyl-terminal hydrolase 28

1

4

High-throughput

0.536

High

1365980

IKZF4
Zinc finger protein Eos

1

3

High-throughput

0.536

High

1365982

ZN408
Zinc finger protein 408

1

1

High-throughput

0.536

High

1365990

ZIM2
Zinc finger imprinted 2

1

2

High-throughput

0.536

High

1365997

UBP25
Ubiquitin carboxyl-terminal hydrolase 25

1

3

High-throughput

0.536

High

1366014

SOX21
Transcription factor SOX-21

1

1

High-throughput

0.536

High

62741

PI4P2
Putative phosphatidylinositol 4-kinase alpha-like protein P2

1

2

High-throughput

0.528

High

520240

ANDR
Androgen receptor

1

5

Small-scale

0.527

High

1365956

ERO1A
ERO1-like protein alpha

1

2

High-throughput

0.523

High

1365973

ZN747
Zinc finger protein 747

1

6

High-throughput

0.523

High

1365989

UGGG2
UDP-glucose:glycoprotein glucosyltransferase 2

1

1

High-throughput

0.523

High

1244022

ZCH12
Zinc finger CCHC domain-containing protein 12

1

0

High-throughput

0.518

High

1365963

HHIP
Hedgehog-interacting protein

1

2

High-throughput

0.515

High

62279

A4FTV9
Histone H2A

1

1

High-throughput

0.515

High

877190

KC1D
Casein kinase I isoform delta

1

6

High-throughput

0.515

High

1088246

TCF15
Transcription factor 15

1

0

High-throughput

0.513

High

1095215

MTAP
S-methyl-5'-thioadenosine phosphorylase

1

0

High-throughput

0.513

High

1109545

CROC4
Protein CROC-4

1

0

High-throughput

0.513

High

1247825

PADI6
Inactive protein-arginine deiminase type-6

1

0

High-throughput

0.513

High

1295276

P66A
Transcriptional repressor p66-alpha

1

0

High-throughput

0.513

High

1336704

CBPC5
Cytosolic carboxypeptidase-like protein 5

1

0

High-throughput

0.513

High

1360272

CSN9
COP9 signalosome complex subunit 9

1

0

High-throughput

0.513

High

1365962

RN157
E3 ubiquitin ligase RNF157

1

0

High-throughput

0.513

High

1366001

INTU
Protein inturned

1

0

High-throughput

0.513

High

575685

GPIX
Platelet glycoprotein IX

1

1

High-throughput

0.512

High

1365954

MFSD3
Major facilitator superfamily domain-containing protein 3

1

2

High-throughput

0.494

High

1365991

CHMP5
Charged multivesicular body protein 5

1

1

High-throughput

0.494

High

164774

GDF8
Growth/differentiation factor 8

1

1

High-throughput

0.489

High

300808

KRT38
Keratin, type I cuticular Ha8

1

17

High-throughput

0.489

High

643199

BMP6
Bone morphogenetic protein 6

1

1

High-throughput

0.489

High

1340400

RASF8
Ras association domain-containing protein 8

1

1

High-throughput

0.489

High

1352203

DQX1
ATP-dependent RNA helicase homolog DQX1

1

2

High-throughput

0.489

High

1365996

FBLN5
Fibulin-5

1

2

High-throughput

0.489

High

1366002

AT7L1
Ataxin-7-like protein 1

1

3

High-throughput

0.489

High

502458

H2A1
Histone H2A type 1

1

1

High-throughput

0.481

High

1365978

MMP28
Matrix metalloproteinase-28

1

1

High-throughput

0.481

High

1365985

GPC5C
G-protein coupled receptor family C group 5 member C

1

1

High-throughput

0.481

High

508364

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

7

High-throughput

0.479

High

943654

SIK1
Serine/threonine-protein kinase SIK1

1

1

Small-scale

0.479

High

1147082

ELOC
Elongin-C

1

1

Small-scale

0.479

High

1220703

RN123
E3 ubiquitin-protein ligase RNF123

1

4

High-throughput

0.479

High

1330888

CGAS
Cyclic GMP-AMP synthase

1

1

High-throughput

0.479

High

1366011

ARI1
E3 ubiquitin-protein ligase ARIH1

1

9

High-throughput

0.479

High

2855

A0A0C4DFY5
G protein-coupled receptor class C group 5 member C

1

1

High-throughput

0.470

High

86923

C0H5X0
MMP28 protein

1

1

High-throughput

0.470

High

509955

SPDE6
Speedy protein E6

1

2

High-throughput

0.470

High

1307984

Q8IUW1
ANKRD10 protein

1

3

High-throughput

0.470

High

1356256

Q8WU57
Ethanolaminephosphotransferase 1

1

1

High-throughput

0.470

High

1365968

Q9BRL4
cyclin-dependent kinase

1

4

High-throughput

0.470

High

1365970

Q9BTE2
GATOR complex protein NPRL3

1

1

High-throughput

0.470

High

166179

AIM2
Interferon-inducible protein AIM2

1

0

High-throughput

0.460

High

238929

DHX16
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16

1

0

High-throughput

0.460

High

352787

F107A
Actin-associated protein FAM107A

1

0

Small-scale

0.460

High

194289

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

1358325

SCFD1
Sec1 family domain-containing protein 1

1

0

Small-scale

0.458

High

1365957

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1110518

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

6

High-throughput

0.445

High

65610

SPE2B
Speedy protein E2B

1

2

High-throughput

0.439

High

1091892

NPRL3
GATOR1 complex protein NPRL3

1

1

High-throughput

0.439

High

1193225

SPDE2
Speedy protein E2

1

2

High-throughput

0.439

High

1365975

EPT1
Ethanolaminephosphotransferase 1

1

1

High-throughput

0.439

High

1365955

DCNL1
DCN1-like protein 1

1

0

High-throughput

0.426

High

1324980

ASCC3
Activating signal cointegrator 1 complex subunit 3

1

3

Small-scale

0.408

High

133550

ACATN
Acetyl-coenzyme A transporter 1

1

1

High-throughput

0.407

High

1310908

ZNT8
Proton-coupled zinc antiporter SLC30A8

1

1

High-throughput

0.407

High

1087071

FSTL1
Follistatin-related protein 1

4

0

High-throughput

0.369

High

771955

CLCN1
Chloride channel protein 1

3

0

High-throughput

0.352

High

946481

FXYD7
FXYD domain-containing ion transport regulator 7

3

0

High-throughput

0.352

High

1165442

COOA1

3

0

High-throughput

0.352

High

1205354

PEX39
Peroxisomal biogenesis factor 39

3

0

High-throughput

0.352

High

1241072

ARMX5
Armadillo repeat-containing X-linked protein 5

3

0

High-throughput

0.352

High

1365971

CA050
Uncharacterized protein C1orf50

3

0

High-throughput

0.352

High

1324328

PYRD2
Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2

2

0

High-throughput

0.330

High

721451

GNA15
Guanine nucleotide-binding protein subunit alpha-15

2

0

High-throughput

0.328

High

1356176

NPRL2
GATOR1 complex protein NPRL2

2

0

High-throughput

0.328

High

458707

SAP
Prosaposin

2

0

High-throughput

0.316

High

652702

AAAD
Arylacetamide deacetylase

2

0

High-throughput

0.316

High

1053159

STP2
Nuclear transition protein 2

2

0

High-throughput

0.316

High

1104555

MSLN
Mesothelin

2

0

High-throughput

0.316

High

1116271

PTC1
Protein patched homolog 1

2

0

High-throughput

0.316

High

1365979

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

2

0

High-throughput

0.316

High

1365984

AT131
Endoplasmic reticulum transmembrane helix translocase

2

0

High-throughput

0.316

High

1365992

CC167
Coiled-coil domain-containing protein 167

2

0

High-throughput

0.316

High

1366006

DOLK
Dolichol kinase

2

0

High-throughput

0.316

High

1366008

MGT4B
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B

2

0

High-throughput

0.316

High

1366009

MA2B2
Epididymis-specific alpha-mannosidase

2

0

High-throughput

0.316

High

562807

CY24A
Cytochrome b-245 light chain

1

0

Small-scale

0.305

High

191456

SIA8E
Alpha-2,8-sialyltransferase 8E

1

0

High-throughput

0.299

High

948121

SELV
Selenoprotein V

1

0

High-throughput

0.299

High

1010683

DCD
Dermcidin

1

0

High-throughput

0.299

High

1126276

GALT3
Polypeptide N-acetylgalactosaminyltransferase 3

1

0

High-throughput

0.299

High

1258788

UB2R2
Ubiquitin-conjugating enzyme E2 R2

1

0

High-throughput

0.299

High

1365960

TAFA4
Chemokine-like protein TAFA-4

1

0

High-throughput

0.299

High

1365972

SCMC3
Mitochondrial adenyl nucleotide antiporter SLC25A23

1

0

High-throughput

0.299

High

689989

CNTFR
Ciliary neurotrophic factor receptor subunit alpha

1

0

High-throughput

0.282

High

1365948

PCSK5
Proprotein convertase subtilisin/kexin type 5

1

0

High-throughput

0.282

High

1365977

WNT5B
Protein Wnt-5b

1

0

High-throughput

0.282

High

317739

NOL4
Nucleolar protein 4

1

0

High-throughput

0.279

Low

335664

GCNT3
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3

1

0

High-throughput

0.279

Low

1251903

THSD4
Thrombospondin type-1 domain-containing protein 4

1

0

High-throughput

0.279

Low

1365994

SLAI2
SLAIN motif-containing protein 2

1

0

High-throughput

0.279

Low

1366012

AP4S1
AP-4 complex subunit sigma-1

1

0

High-throughput

0.279

Low

76272

B4DJ51
Calmodulin 1

1

0

High-throughput

0.268

Low

1365981

Q9H669
cDNA: FLJ22558 fis, clone HSI01557

1

0

High-throughput

0.268

Low

1094067

RM28
Large ribosomal subunit protein bL28m

1

0

Small-scale

0.261

Low

66644

CC85C
Coiled-coil domain-containing protein 85C

1

0

High-throughput

0.251

Low

416968

CY24B
NADPH oxidase 2

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025