Protein: CLF1
Pre-mRNA-splicing factor CLF1 (Crooked neck-like factor 1) (PRP19-associated complex protein 77) (Synthetic lethal with CDC40 protein 3)

Gene: CLF1
Organism: Saccharomyces cerevisiae S288C
Interactions: 78
UniProt ID: Q12309

Gene Ontology (top 5):
GO:0000245 - spliceosomal complex assembly
GO:0000354 - cis assembly of pre-catalytic spliceosome
GO:0000398 - mRNA splicing, via spliceosome
GO:0000785 - chromatin
GO:0000974 - Prp19 complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

977088

CEF1
Pre-mRNA-splicing factor CEF1

10

12

Small-scale

0.977

High

861084

SYF2
Pre-mRNA-splicing factor SYF2

5

1

Small-scale

0.925

High

655771

PRP45
Pre-mRNA-processing protein 45

5

8

Small-scale

0.921

High

692376

PRP19
Pre-mRNA-processing factor 19

14

20

Small-scale

0.762

High

978488

SYF1
Pre-mRNA-splicing factor SYF1

8

10

Small-scale

0.752

High

748097

NTC20
Pre-mRNA-splicing factor NTC20

7

1

Small-scale

0.750

High

985865

SN309
Pre-mRNA-splicing factor SNT309

7

1

Small-scale

0.750

High

598657

ISY1
Pre-mRNA-splicing factor ISY1

6

6

Small-scale

0.740

High

1014927

CWC2
Pre-mRNA-splicing factor CWC2

6

8

Small-scale

0.733

High

657779

YJU2
Splicing factor YJU2

6

6

Small-scale

0.731

High

1015445

PRP46
Pre-mRNA-splicing factor PRP46

5

20

Small-scale

0.713

High

622351

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22

5

18

Small-scale

0.708

High

987205

SP382
Pre-mRNA-splicing factor SPP382

4

3

Small-scale

0.699

High

971705

CUS1
Cold sensitive U2 snRNA suppressor 1

4

3

Small-scale

0.692

High

704735

PRP8
Pre-mRNA-splicing factor 8

4

11

Small-scale

0.691

High

731786

SN114
Pre-mRNA-splicing factor SNU114

4

15

Small-scale

0.691

High

746888

SLT11
Pre-mRNA-splicing factor SLT11

4

5

Small-scale

0.691

High

980239

RSE1
Pre-mRNA-splicing factor RSE1

4

4

Small-scale

0.691

High

697276

BRR2
Pre-mRNA-splicing helicase BRR2

4

20

Small-scale

0.686

High

766976

RSMB
Small nuclear ribonucleoprotein-associated protein B

4

12

Small-scale

0.686

High

836950

SF3B1
U2 snRNP component HSH155

4

12

Small-scale

0.682

High

997045

RU2A
U2 small nuclear ribonucleoprotein A'

4

13

Small-scale

0.676

High

859463

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

3

16

High-throughput

0.671

High

861587

CWC22
Pre-mRNA-splicing factor CWC22

3

3

High-throughput

0.662

High

770347

RUXG
Small nuclear ribonucleoprotein G

3

20

High-throughput

0.643

High

996591

NCBP2
Nuclear cap-binding protein subunit 2

3

20

High-throughput

0.640

High

732407

MUD2
Splicing factor MUD2

3

0

Small-scale

0.627

High

733102

NTR2
Pre-mRNA-splicing factor NTR2

2

1

Small-scale

0.611

High

865379

CWC25
Pre-mRNA-splicing factor CWC25

2

2

High-throughput

0.611

High

976135

CWC21
Pre-mRNA-splicing factor CWC21

2

2

High-throughput

0.601

High

589465

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

2

18

High-throughput

0.584

High

795434

SMD3
Small nuclear ribonucleoprotein Sm D3

2

20

Small-scale

0.584

High

873679

RUXF
Small nuclear ribonucleoprotein F

2

12

Small-scale

0.584

High

970252

SMD1
Small nuclear ribonucleoprotein Sm D1

2

3

Small-scale

0.584

High

986609

SMD2
Small nuclear ribonucleoprotein Sm D2

2

6

Small-scale

0.584

High

856947

CWC23
Pre-mRNA-splicing factor CWC23

2

7

Small-scale

0.558

High

698740

ORC2
Origin recognition complex subunit 2

1

0

Small-scale

0.549

High

987742

URN1
Pre-mRNA-splicing factor URN1

1

1

High-throughput

0.536

High

972434

SLU7
Pre-mRNA-splicing factor SLU7

2

1

Small-scale

0.533

High

703291

PRP40
Pre-mRNA-processing protein PRP40

1

3

Small-scale

0.527

High

495319

HSP72
Heat shock protein SSA2

2

11

High-throughput

0.504

High

554256

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

19

High-throughput

0.479

High

586540

PRP9
Pre-mRNA-splicing factor PRP9

1

4

High-throughput

0.479

High

616123

PRP28
Pre-mRNA-splicing ATP-dependent RNA helicase PRP28

1

14

Small-scale

0.479

High

629405

BUD31
Pre-mRNA-splicing factor BUD31

1

5

High-throughput

0.479

High

692440

PRP21
Pre-mRNA-splicing factor PRP21

1

6

High-throughput

0.479

High

710239

NCBP1
Nuclear cap-binding protein complex subunit 1

1

3

High-throughput

0.479

High

746365

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

20

Small-scale

0.479

High

768263

LSM5
U6 snRNA-associated Sm-like protein LSm5

1

3

Small-scale

0.479

High

775707

IST3
U2 snRNP component IST3

1

16

High-throughput

0.479

High

775731

MSL1
U2 small nuclear ribonucleoprotein B''

1

20

High-throughput

0.479

High

778645

PRP17
Pre-mRNA-processing factor 17

1

20

High-throughput

0.479

High

809557

CWC26
Pre-mRNA-splicing factor CWC26

1

3

High-throughput

0.479

High

865193

CUS2
Cold sensitive U2 snRNA suppressor 2

1

20

Small-scale

0.479

High

865990

LSM7
U6 snRNA-associated Sm-like protein LSm7

1

20

Small-scale

0.479

High

884838

LSM3
U6 snRNA-associated Sm-like protein LSm3

1

20

Small-scale

0.479

High

971115

SPP2
Pre-mRNA-splicing factor SPP2

1

1

High-throughput

0.479

High

977581

CWC15
Pre-mRNA-splicing factor CWC15

1

1

High-throughput

0.479

High

987147

LSM6
U6 snRNA-associated Sm-like protein LSm6

1

12

Small-scale

0.479

High

989435

RDS3
Pre-mRNA-splicing factor RDS3

1

2

High-throughput

0.479

High

991158

PRP11
Pre-mRNA-splicing factor PRP11

1

5

High-throughput

0.479

High

1015444

RUXE
Small nuclear ribonucleoprotein E

1

6

Small-scale

0.479

High

1015446

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

1

3

Small-scale

0.479

High

1015447

HSH49
Protein HSH49

1

10

High-throughput

0.479

High

972656

XRN2
5'-3' exoribonuclease 2

1

4

Small-scale

0.437

High

997007

AP3D
AP-3 complex subunit delta

1

1

High-throughput

0.437

High

513225

SSB1
Ribosome-associated molecular chaperone SSB1

1

12

High-throughput

0.407

High

705813

HSP78
Heat shock protein 78, mitochondrial

1

6

High-throughput

0.407

High

829727

RL4B
Large ribosomal subunit protein uL4B

1

4

High-throughput

0.407

High

748202

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.279

Low

514657

FUS1
Nuclear fusion protein FUS1

1

0

High-throughput

0.265

Low

636094

CSM1
Monopolin complex subunit CSM1

1

0

Small-scale

0.265

Low

744858

GPX2
Glutathione peroxidase-like peroxiredoxin 2

1

0

High-throughput

0.265

Low

1015368

DAD1
DASH complex subunit DAD1

1

0

High-throughput

0.251

Low

1015387

CENPH
Inner kinetochore subunit MCM16

1

0

High-throughput

0.251

Low

733487

YK21
Uncharacterized protein YKR041W

1

0

High-throughput

0.249

Low

696610

SEC17
Alpha-soluble NSF attachment protein

1

0

High-throughput

0.238

Low

748099

YB40
Putative uncharacterized protein YBR190W

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024