Protein: PIS
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (EC 2.7.8.11) (Phosphatidylinositol synthase) (PI synthase) (PtdIns synthase)

Gene: PIS, PIS1
Organism: Saccharomyces cerevisiae S288C
Interactions: 56
UniProt ID: P06197

Gene Ontology (top 5):
GO:0003881 - CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

411151

PIS
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

2

0

High-throughput

0.751

High

411188

MPS3
Spindle pole body assembly component MPS3

2

0

High-throughput

0.575

High

411160

GAP1
General amino-acid permease GAP1

1

1

Small-scale

0.552

High

411157

HSC82
ATP-dependent molecular chaperone HSC82

2

0

High-throughput

0.547

High

411158

NCPR
NADPH--cytochrome P450 reductase

1

1

High-throughput

0.541

High

411172

GCS1
ADP-ribosylation factor GTPase-activating protein GCS1

1

1

High-throughput

0.541

High

411194

TMEDA
Endoplasmic reticulum vesicle protein 25

1

2

High-throughput

0.541

High

411202

ERP1
Protein ERP1

1

2

High-throughput

0.541

High

411153

HSP71
Heat shock protein SSA1

2

1

High-throughput

0.533

High

411155

CP51
Lanosterol 14-alpha demethylase CYP51

1

0

High-throughput

0.518

High

411165

PPZ1
Serine/threonine-protein phosphatase PP-Z1

1

0

High-throughput

0.518

High

411171

RER2
Dehydrodolichyl diphosphate synthase complex subunit RER2

1

0

High-throughput

0.518

High

411176

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.518

High

411178

SSH1
Sec sixty-one protein homolog

1

0

High-throughput

0.518

High

411179

MSC7
Putative aldehyde dehydrogenase-like protein YHR039C

1

0

High-throughput

0.518

High

411185

AYR1
NADPH-dependent 1-acyldihydroxyacetone phosphate reductase

1

0

High-throughput

0.518

High

411186

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.518

High

411193

ERG5
C-22 sterol desaturase ERG5

1

0

High-throughput

0.518

High

411196

OSH6
Oxysterol-binding protein homolog 6

1

0

High-throughput

0.518

High

411197

SHR3
Secretory component protein SHR3

1

0

High-throughput

0.518

High

411200

TCB3
Tricalbin-3

1

0

High-throughput

0.518

High

411204

TMS1
Membrane protein TMS1

1

0

High-throughput

0.518

High

411205

SEY1
Protein SEY1

1

0

High-throughput

0.518

High

411182

MST28
Multicopy suppressor of SEC21 protein 28

1

1

High-throughput

0.508

High

411173

SIS2
Phosphopantothenoylcysteine decarboxylase subunit SIS2

1

1

High-throughput

0.494

High

411174

CAB3
Coenzyme A biosynthesis protein 3

1

1

High-throughput

0.494

High

411163

SEC14
SEC14 cytosolic factor

1

0

High-throughput

0.486

High

411187

GST1
Glutathione S-transferase 1

1

0

High-throughput

0.486

High

411199

PEX29
Peroxisomal membrane protein PEX29

1

0

High-throughput

0.486

High

411201

USA1
U1 SNP1-associating protein 1

1

0

High-throughput

0.486

High

411203

LAM6
Membrane-anchored lipid-binding protein LAM6

1

0

High-throughput

0.486

High

411154

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.479

High

411166

PMT2
Dolichyl-phosphate-mannose--protein mannosyltransferase 2

1

1

High-throughput

0.479

High

411169

EMP24
Endosomal protein P24B

1

1

High-throughput

0.479

High

411170

PMT1
Dolichyl-phosphate-mannose--protein mannosyltransferase 1

1

1

High-throughput

0.479

High

411181

UIP3
ULP1-interacting protein 3

1

1

High-throughput

0.464

High

411161

ACO1
Acyl-CoA desaturase 1

1

0

High-throughput

0.458

High

411162

PSA1
Proteasome subunit alpha type-1

1

0

High-throughput

0.458

High

411164

CWH43
Protein CWH43

1

0

High-throughput

0.458

High

411180

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

411183

SPF1
Endoplasmic reticulum transmembrane helix translocase

1

0

High-throughput

0.458

High

411191

ALG9
Alpha-1,2-mannosyltransferase ALG9

1

0

High-throughput

0.458

High

411192

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

411189

ERV29
ER-derived vesicles protein ERV29

1

0

High-throughput

0.438

High

411195

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.438

High

411175

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

411190

COPA
Coatomer subunit alpha

1

1

High-throughput

0.437

High

411168

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.407

High

411167

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.282

High

411198

ROD1
Protein ROD1

1

0

High-throughput

0.282

High

411177

NTM1
Alpha N-terminal protein methyltransferase 1

1

0

High-throughput

0.265

Low

411152

DED1
ATP-dependent RNA helicase DED1

1

0

High-throughput

0.249

Low

411156

HEM6
Oxygen-dependent coproporphyrinogen-III oxidase

1

0

High-throughput

0.249

Low

411159

VATA
V-type proton ATPase catalytic subunit A

1

0

High-throughput

0.249

Low

411184

SSB2
Ribosome-associated molecular chaperone SSB2

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024