Protein: HOT
Hydroxyacid-oxoacid transhydrogenase, mitochondrial (HOT) (EC 1.1.99.24) (Alcohol dehydrogenase iron-containing protein 1) (ADHFe1) (Fe-containing alcohol dehydrogenase)

Gene: HOT, ADHFE1
Organism: Homo sapiens
Interactions: 4
UniProt ID: Q8IWW8

Gene Ontology (top 5):
GO:0004022 - alcohol dehydrogenase (NAD+) activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006103 - 2-oxoglutarate metabolic process
GO:0006629 - lipid metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

893502

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

0

High-throughput

0.518

High

538306

LIPC
Hepatic triacylglycerol lipase

1

0

High-throughput

0.282

High

1163040

H2B2E
Histone H2B type 2-E

1

0

High-throughput

0.269

Low

1227017

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025