Protein: TPH2
Tryptophan 5-hydroxylase 2 (EC 1.14.16.4) (Neuronal tryptophan hydroxylase) (Tryptophan 5-monooxygenase 2)

Gene: TPH2
Organism: Homo sapiens
Interactions: 5
UniProt ID: Q8IWU9

Gene Ontology (top 5):
GO:0004510 - tryptophan 5-monooxygenase activity
GO:0005506 - iron ion binding
GO:0005829 - cytosol
GO:0009072 - aromatic amino acid metabolic process
GO:0042427 - serotonin biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

607896

TPH1
Tryptophan 5-hydroxylase 1

1

3

High-throughput

0.665

High

1311070

DJC12
DnaJ homolog subfamily C member 12

2

3

High-throughput

0.558

High

565964

EF2
Elongation factor 2

1

0

High-throughput

0.458

High

971754

1433E
14-3-3 protein epsilon

1

0

Small-scale

0.426

High

1311069

SYBU
Syntabulin

2

0

High-throughput

0.328

High


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Last updated: 11Aug2025