Protein: TPH1
Tryptophan 5-hydroxylase 1 (EC 1.14.16.4) (Tryptophan 5-monooxygenase 1)

Gene: TPH1
Organism: Homo sapiens
Interactions: 15
UniProt ID: P17752

Gene Ontology (top 5):
GO:0002576 - platelet degranulation
GO:0004510 - tryptophan 5-monooxygenase activity
GO:0005506 - iron ion binding
GO:0005829 - cytosol
GO:0009072 - aromatic amino acid metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

607896

TPH2
Tryptophan 5-hydroxylase 2

1

3

High-throughput

0.665

High

220738

PPIP1
Proline-serine-threonine phosphatase-interacting protein 1

2

0

High-throughput

0.580

High

607899

DJC12
DnaJ homolog subfamily C member 12

2

3

High-throughput

0.574

High

607891

1433Z
14-3-3 protein zeta/delta

1

5

Small-scale

0.501

High

607890

COF1
Cofilin-1

1

0

High-throughput

0.493

High

607893

BECN1
Beclin-1

1

0

High-throughput

0.493

High

421460

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

607892

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

340294

YETS4
YEATS domain-containing protein 4

2

0

High-throughput

0.328

High

607894

RFWD3
E3 ubiquitin-protein ligase RFWD3

2

0

High-throughput

0.328

High

607895

MCM10
Protein MCM10 homolog

2

0

High-throughput

0.328

High

607898

GORS2
Golgi reassembly-stacking protein 2

2

0

High-throughput

0.316

High

345150

ZMYM6
Zinc finger MYM-type protein 6

1

0

High-throughput

0.268

Low

607897

BOD1
Biorientation of chromosomes in cell division protein 1

1

0

High-throughput

0.268

Low

371102

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025