HitPredict - High confidence protein-protein interactions

Protein: DNA2
DNA replication ATP-dependent helicase/nuclease DNA2 (DNA replication ATP-dependent helicase-like homolog) [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)]

Gene: DNA2
Organism: Xenopus laevis
Interactions: 7
UniProt ID: Q8QHA5

Gene Ontology (top 5):
GO:0000076 - DNA replication checkpoint signaling
GO:0000729 - DNA double-strand break processing
GO:0003677 - DNA binding
GO:0003723 - RNA binding
GO:0004518 - nuclease activity

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
1180216	Q2TAV8 WD repeat and HMG-box DNA-binding protein 1	1	16	Small-scale	0.479	High
1208421	Q5MPF8 non-specific serine/threonine protein kinase	1	8	Small-scale	0.479	High
1009571	P79922 DNA	1	0	High-throughput	0.458	High
1204153	MCM10 Protein MCM10 homolog	1	0	Small-scale	0.458	High
1251232	NBN Nibrin	1	0	Small-scale	0.458	High
1341382	PCM1 Pericentriolar material 1 protein	1	0	Small-scale	0.458	High
1225455	Q642R6 MGC83295 protein	1	0	Small-scale	0.249	Low

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Last updated: 11Aug2025