Interactor 1: IFFO1 (Q0D2I5)
Non-homologous end joining factor IFFO1 (NHEJ factor IFFO1) (Intermediate filament family orphan 1) (Tumor antigen HOM-TES-103)
Gene: IFFO1

Interactor 2: XRCC4 (Q13426)
DNA repair protein XRCC4 (hXRCC4) (X-ray repair cross-complementing protein 4) [Cleaved into: Protein XRCC4, C-terminus (XRCC4/C)]
Gene: XRCC4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 0.60 0.728

The method score is based on:

Property Details
Experiments 26186194, 16189514, 28514442, 33961781, 31548606
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, x-ray crystallography, two hybrid pooling approach
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0006303 - double-strand break repair via nonhomologous end joining
GO:0035861 - site of double-strand break
GO:1990166 - protein localization to site of double-strand break
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 559
Hs

1 336
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024