Protein: CLU
Clustered mitochondria protein 1 (Translation initiation factor 31) (eIF3-associated protein p135)

Gene: CLU, CLU1
Organism: Saccharomyces cerevisiae S288C
Interactions: 182
UniProt ID: Q03690

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0005737 - cytoplasm
GO:0007005 - mitochondrion organization
GO:0010494 - cytoplasmic stress granule

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

525000

HSP71
Heat shock protein SSA1

3

8

High-throughput

0.656

High

393253

HSP82
ATP-dependent molecular chaperone HSP82

3

3

High-throughput

0.633

High

792224

GBLP
Small ribosomal subunit protein RACK1

2

1

High-throughput

0.611

High

923113

BRE5
UBP3-associated protein BRE5

2

1

High-throughput

0.601

High

1030565

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

2

3

High-throughput

0.601

High

701738

URA7
CTP synthase 1

2

0

High-throughput

0.595

High

796117

IMB2
Importin subunit beta-2

2

0

High-throughput

0.595

High

1042359

GCN5
Histone acetyltransferase GCN5

2

3

High-throughput

0.574

High

727287

HS104
Heat shock protein 104

2

2

High-throughput

0.571

High

553649

ERF1
Eukaryotic peptide chain release factor subunit 1

2

0

High-throughput

0.563

High

793521

MAK5
ATP-dependent RNA helicase MAK5

2

0

High-throughput

0.563

High

410316

RL25
Large ribosomal subunit protein uL23

2

0

High-throughput

0.559

High

558850

CAF20
Cap-associated protein CAF20

2

0

High-throughput

0.559

High

527560

HSP72
Heat shock protein SSA2

2

8

High-throughput

0.552

High

742291

HSP7F
Heat shock protein homolog SSE1

2

11

High-throughput

0.552

High

819663

SSB2
Ribosome-associated molecular chaperone SSB2

2

8

High-throughput

0.552

High

619382

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

2

2

High-throughput

0.537

High

1029636

MCE1
mRNA-capping enzyme subunit alpha

2

2

High-throughput

0.537

High

364718

CDK1
Cyclin-dependent kinase 1

1

4

High-throughput

0.536

High

486512

TBA3
Tubulin alpha-3 chain

1

1

High-throughput

0.536

High

740004

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

1

Small-scale

0.536

High

802587

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.536

High

826374

SGN1
RNA-binding protein SGN1

1

2

High-throughput

0.536

High

1039616

NOG1
Nucleolar GTP-binding protein 1

1

1

High-throughput

0.536

High

1043595

HEL2
E3 ubiquitin-protein ligase HEL2

1

1

High-throughput

0.536

High

850183

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

1

High-throughput

0.533

High

1043591

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

1

Small-scale

0.527

High

531392

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.513

High

636941

FAR1
Cyclin-dependent kinase inhibitor FAR1

1

0

High-throughput

0.513

High

743280

PP12
Serine/threonine-protein phosphatase PP1-2

1

0

High-throughput

0.513

High

813963

RBG1
Ribosome-interacting GTPase 1

1

0

High-throughput

0.513

High

836871

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.513

High

863095

CWC26
Pre-mRNA-splicing factor CWC26

1

0

High-throughput

0.513

High

868441

LCF4
Long-chain-fatty-acid--CoA ligase 4

1

0

High-throughput

0.513

High

1043598

PRP11
Pre-mRNA-splicing factor PRP11

1

0

High-throughput

0.513

High

1043608

INP53
Polyphosphatidylinositol phosphatase INP53

1

0

High-throughput

0.513

High

518119

SSBP1
Single-stranded nucleic acid-binding protein

1

4

High-throughput

0.501

High

864078

YJO4
Uncharacterized protein YJL144W

1

0

High-throughput

0.493

High

923958

YNX4
Uncharacterized globin-like protein YNL234W

1

0

High-throughput

0.493

High

598434

TUP1
General transcriptional corepressor TUP1

1

2

High-throughput

0.489

High

625044

PRP6
Pre-mRNA-splicing factor 6

1

3

High-throughput

0.489

High

763014

SPT7
SAGA complex subunit SPT7

1

3

High-throughput

0.489

High

793449

ATR
Serine/threonine-protein kinase MEC1

1

2

High-throughput

0.489

High

793984

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

4

High-throughput

0.489

High

808546

TEM1
Protein TEM1

1

1

High-throughput

0.489

High

825474

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

1

High-throughput

0.489

High

923192

NOG2
Nucleolar GTP-binding protein 2

1

1

High-throughput

0.489

High

1043592

KU80
ATP-dependent DNA helicase II subunit 2

1

2

High-throughput

0.489

High

149935

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.479

High

432686

RL7A
Large ribosomal subunit protein uL30A

1

1

High-throughput

0.479

High

579980

HSC82
ATP-dependent molecular chaperone HSC82

1

3

High-throughput

0.479

High

601118

RL8A
Large ribosomal subunit protein eL8A

1

2

High-throughput

0.479

High

604974

MDHM
Malate dehydrogenase, mitochondrial

1

1

Small-scale

0.479

High

646522

RAD53
Serine/threonine-protein kinase RAD53

1

2

High-throughput

0.479

High

682370

SPB4
ATP-dependent rRNA helicase SPB4

1

1

High-throughput

0.479

High

689122

RL16A
Large ribosomal subunit protein uL13A

1

2

High-throughput

0.479

High

689276

RL16B
Large ribosomal subunit protein uL13B

1

2

High-throughput

0.479

High

709958

BMH1
Protein BMH1

1

6

High-throughput

0.479

High

747556

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.479

High

778512

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.479

High

781255

RL14A
Large ribosomal subunit protein eL14A

1

1

High-throughput

0.479

High

795516

ATG8
Autophagy-related protein 8

1

2

High-throughput

0.479

High

802367

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.479

High

812112

DHH1
ATP-dependent RNA helicase DHH1

1

1

High-throughput

0.479

High

814032

IF2P
Eukaryotic translation initiation factor 5B

1

1

High-throughput

0.479

High

817286

ARB1
ABC transporter ATP-binding protein ARB1

1

1

Small-scale

0.479

High

824940

TM108
Protein TMA108

1

1

High-throughput

0.479

High

1025021

NUM1
Nuclear migration protein NUM1

1

13

High-throughput

0.479

High

1026814

CDC14
Tyrosine-protein phosphatase CDC14

1

2

Small-scale

0.479

High

1042216

TOM1
E3 ubiquitin-protein ligase TOM1

1

1

High-throughput

0.479

High

1043606

NEW1
[NU+] prion formation protein 1

1

1

High-throughput

0.479

High

403640

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

Small-scale

0.458

High

427426

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.458

High

433828

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.458

High

434433

RL15A
Large ribosomal subunit protein eL15A

1

0

High-throughput

0.458

High

435329

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

436147

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

442091

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

455240

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

514811

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

531870

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.458

High

570129

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

657124

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

Small-scale

0.458

High

674811

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

748025

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

750771

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.458

High

779933

YRA2
RNA annealing protein YRA2

1

0

High-throughput

0.458

High

780059

EAP1
Protein EAP1

1

0

High-throughput

0.458

High

792568

RL32
Large ribosomal subunit protein eL32

1

0

High-throughput

0.458

High

797787

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.458

High

803672

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

806993

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

0

High-throughput

0.458

High

835880

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.458

High

874504

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

918973

PESC
Pescadillo homolog

1

0

High-throughput

0.458

High

924444

IGO1
mRNA stability protein IGO1

1

0

Small-scale

0.458

High

1033538

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

1038742

XRN2
5'-3' exoribonuclease 2

1

0

High-throughput

0.458

High

1040547

ESP1
Separin

1

0

High-throughput

0.458

High

1043597

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.458

High

1043601

SGO1
Shugoshin

1

0

High-throughput

0.458

High

1043602

MCA1
Metacaspase-1

1

0

High-throughput

0.458

High

1043604

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

1043610

CSN10
COP9 signalosome complex subunit 10

1

0

Small-scale

0.458

High

1043612

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.458

High

546098

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.445

High

742936

HSP79
Heat shock protein homolog SSE2

1

12

High-throughput

0.445

High

816377

HSP7E
Heat shock protein SSC3, mitochondrial

1

10

High-throughput

0.445

High

816892

NUG1
Nuclear GTP-binding protein NUG1

1

1

High-throughput

0.445

High

893053

PHB2
Prohibitin-2

1

1

High-throughput

0.445

High

671067

SIS1
Protein SIS1

1

2

High-throughput

0.437

High

680018

CDC48
Cell division control protein 48

1

5

High-throughput

0.437

High

689640

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.437

High

720935

SEC1
Protein transport protein SEC1

1

1

High-throughput

0.437

High

779337

CENPA
Histone H3-like centromeric protein CSE4

1

1

High-throughput

0.437

High

803057

MUP3
Low-affinity methionine permease

1

1

High-throughput

0.437

High

963688

H3
Histone H3

1

1

High-throughput

0.437

High

1043605

AP3D
AP-3 complex subunit delta

1

1

High-throughput

0.437

High

676299

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

1043590

ARX1
Probable metalloprotease ARX1

1

0

High-throughput

0.426

High

1043609

HSP42
Heat shock protein 42

1

0

High-throughput

0.426

High

817395

PIC2
Mitochondrial phosphate carrier protein 2

1

2

High-throughput

0.407

High

893334

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

1

High-throughput

0.407

High

926275

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

3

High-throughput

0.407

High

1036335

ADA2
SAGA complex subunit ADA2

1

1

High-throughput

0.407

High

1043611

RUVB2
RuvB-like protein 2

1

2

High-throughput

0.407

High

1043614

GLT1
Glutamate synthase [NADH]

1

1

High-throughput

0.407

High

449363

RAD3
General transcription and DNA repair factor IIH helicase subunit XPD/RAD3

2

0

High-throughput

0.307

High

675347

RAD51
DNA repair protein RAD51

2

0

High-throughput

0.307

High

858461

TAF1
Transcription initiation factor TFIID subunit 1

2

0

High-throughput

0.307

High

415242

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.279

Low

726016

NTH1
Endonuclease III homolog 1

1

0

High-throughput

0.279

Low

737114

CDC11
Cell division control protein 11

1

0

High-throughput

0.279

Low

779443

MAOM
NAD-dependent malic enzyme, mitochondrial

1

0

High-throughput

0.279

Low

807265

SPT8
SAGA complex subunit SPT8

1

0

High-throughput

0.279

Low

817620

UTP7
U3 small nucleolar RNA-associated protein 7

1

0

High-throughput

0.279

Low

898189

SPT20
SAGA complex subunit SPT20

1

0

High-throughput

0.279

Low

918562

YG2A
Zinc finger protein YGR067C

1

0

High-throughput

0.279

Low

1031764

CIK1
Spindle pole body-associated protein CIK1

1

0

High-throughput

0.279

Low

1043593

SEN15
tRNA-splicing endonuclease subunit SEN15

1

0

High-throughput

0.279

Low

1043594

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

0

High-throughput

0.279

Low

1043600

PSR2
Probable phosphatase PSR2

1

0

High-throughput

0.279

Low

1043607

HFI1
SAGA complex subunit HFI1

1

0

High-throughput

0.279

Low

1043613

YP015
Zinc finger protein YPR015C

1

0

High-throughput

0.279

Low

1043616

SUS1
SAGA complex subunit SUS1

1

0

High-throughput

0.279

Low

554536

RT13
Small ribosomal subunit protein mS27

1

0

High-throughput

0.269

Low

383874

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

432908

RL9A
Large ribosomal subunit protein uL6A

1

0

High-throughput

0.249

Low

503217

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

504394

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

512625

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.249

Low

513195

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

647201

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.249

Low

708044

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

739751

SPT16
FACT complex subunit SPT16

1

0

High-throughput

0.249

Low

753563

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

763990

SPT10
Protein SPT10

1

0

High-throughput

0.249

Low

764148

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

795188

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

797044

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.249

Low

806810

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.249

Low

812616

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

818269

NSA2
Ribosome biogenesis protein NSA2

1

0

High-throughput

0.249

Low

826790

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

925382

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

1038392

RL21A
Large ribosomal subunit protein eL21A

1

0

High-throughput

0.249

Low

1043596

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

1043603

ESA1
Histone acetyltransferase ESA1

1

0

Small-scale

0.249

Low

1043617

ENV10
SRP-independent targeting protein 2

1

0

High-throughput

0.249

Low

427039

FUR4
Uracil permease

1

0

High-throughput

0.232

Low

456450

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

0

High-throughput

0.232

Low

613873

ERD2
ER lumen protein-retaining receptor

1

0

High-throughput

0.232

Low

636342

ACO1
Acyl-CoA desaturase 1

1

0

High-throughput

0.232

Low

747201

PMP1
Plasma membrane ATPase proteolipid 1

1

0

High-throughput

0.232

Low

802496

LAG1
Ceramide synthase LAG1

1

0

High-throughput

0.232

Low

812206

ILV3
Dihydroxy-acid dehydratase, mitochondrial

1

0

High-throughput

0.232

Low

850632

SA155
SIT4-associating protein SAP155

1

0

High-throughput

0.232

Low

916448

SCS3
Acyl-coenzyme A diphosphatase SCS3

1

0

High-throughput

0.232

Low

916774

ERG25
C-4 methylsterol oxidase ERG25

1

0

High-throughput

0.232

Low

918236

YG1A
Uncharacterized membrane protein YGR016W

1

0

High-throughput

0.232

Low

1043599

CRLS1
Cardiolipin synthase

1

0

High-throughput

0.232

Low

1043615

YB111
Uncharacterized helicase-like protein YBL111C

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025