HitPredict

Interactor 1: ELAV1 (P70372)
ELAV-like protein 1 (Elav-like generic protein) (Hu-antigen R) (HuR) (MelG)
Gene: Elavl1

Interactor 2: HDAC4 (Q6NZM9)
Histone deacetylase 4 (HD4) (EC 3.5.1.98)
Gene: HDAC4

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	31040226
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008283 - cell population proliferation and 1 others more... GO:0019901 - protein kinase binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 326 Mm			1 1076
+	Mm
		1221946 ELAV2_MOUSE (1-326): 2.77e-84: 260: 68.24		HDAC4_MOUSE (1-1065): 0: 841: 100.00
+	Mm
		1221949 ELAV3_MOUSE (1-326): 5.04e-80: 249: 61.96		HDAC4_MOUSE (1-1065): 0: 841: 100.00
+	Hs
		940976 ELAV1_HUMAN (1-326): 1.1e-85: 262: 98.47		HDAC4_HUMAN (1-1064): 0: 812: 93.56
+	Mm
		1223271 ELAV4_MOUSE (82-326): 7.36e-38: 140: 18.62		HDAC4_MOUSE (1-1065): 0: 841: 100.00
+	Hs
		550528 PABP1_HUMAN (6-253): 1.01e-43: 160: 20.22		HDAC5_HUMAN (1-1076): 0: 662: 54.58
+	Hs
		1102041 PABP4_HUMAN (6-204): 6.01e-44: 161: 24.42		HDAC2_HUMAN (664-1074): 7.02e-161: 486: 22.84
+	Hs
		550390 PABP1_HUMAN (6-253): 1.01e-43: 160: 20.22		HDAC2_HUMAN (664-1074): 7.02e-161: 486: 22.84
+	Hs
		1152666 ELAV1_HUMAN (1-326): 1.1e-85: 262: 98.47		HDAC6_HUMAN (644-1033): 2.59e-111: 376: 36.74
+	Hs
		1102122 PABP4_HUMAN (6-204): 6.01e-44: 161: 24.42		HDAC6_HUMAN (644-1033): 2.59e-111: 376: 36.74
+	Hs
		550501 PABP1_HUMAN (6-253): 1.01e-43: 160: 20.22		HDAC6_HUMAN (644-1033): 2.59e-111: 376: 36.74