HitPredict

Interactor 1: F6XY72 (F6XY72)
Histidine protein kinase NDKB (EC 2.7.13.3) (EC 2.7.4.6)
Gene: NME2

Interactor 2: NDK3 (Q13232)
Nucleoside diphosphate kinase 3 (NDK 3) (NDP kinase 3) (EC 2.7.4.6) (DR-nm23) (Nucleoside diphosphate kinase C) (NDPKC) (nm23-H3)
Gene: NME3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	NDK~NDK
Common GO terms	GO:0004550 - nucleoside diphosphate kinase activity GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0006183 - GTP biosynthetic process GO:0006228 - UTP biosynthetic process and 1 others more... GO:0006241 - CTP biosynthetic process
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 82 Hs			1 169
+	Hs
		607647 NDKB_HUMAN (1-82): 5.54e-41: 133: 93.90		NDK3_HUMAN (1-169): 2.08e-91: 264: 100.00
+	Hs
		607586 NDKB_HUMAN (1-82): 5.54e-41: 133: 93.90		NDKB_HUMAN (18-169): 4.26e-91: 263: 63.82
+	Hs
		548904 NDKA_HUMAN (1-82): 2.56e-40: 131: 80.49		NDK3_HUMAN (1-169): 2.08e-91: 264: 100.00
+	Hs
		548860 NDKB_HUMAN (1-82): 5.54e-41: 133: 93.90		NDKA_HUMAN (18-169): 8.05e-89: 257: 65.79
+	Dm
		65459 NDKA_DROME (2-82): 2.97e-38: 126: 71.61		A8E6J4_DROME (1-169): 5.98e-91: 264: 61.54
+	Hs
		548853 NDKA_HUMAN (1-82): 2.56e-40: 131: 80.49		NDKA_HUMAN (18-169): 8.05e-89: 257: 65.79
+	Dm
		445605 NDKA_DROME (2-82): 2.97e-38: 126: 71.61		NDKA_DROME (17-169): 1.57e-87: 254: 65.36
+	Ce
		1274720 Q93576_CAEEL (1-82): 2.45e-39: 128: 67.07		Q93576_CAEEL (18-169): 1.13e-81: 239: 56.21
+	Hs
		135574 NDKB_HUMAN (1-82): 5.54e-41: 133: 93.90		NDKM_HUMAN (20-165): 7e-77: 229: 60.96
+	Hs
		135572 NDKA_HUMAN (1-82): 2.56e-40: 131: 80.49		NDKM_HUMAN (20-165): 7e-77: 229: 60.96
+	Hs
		233739 NDKB_HUMAN (1-82): 5.54e-41: 133: 93.90		NDK8_HUMAN (33-169): 4.69e-77: 227: 61.31
+	Hs
		233736 NDKA_HUMAN (1-82): 2.56e-40: 131: 80.49		NDK8_HUMAN (33-169): 4.69e-77: 227: 61.31
+	Hs
		233758 Q32Q12_HUMAN (1-82): 2.29e-38: 130: 80.49		NDK8_HUMAN (33-169): 4.69e-77: 227: 61.31
+	At
		249500 NDK2_ARATH (1-82): 8.73e-37: 124: 51.22		NDK2_ARATH (16-169): 5.53e-78: 233: 51.30
+	Hs
		607668 NDKB_HUMAN (1-82): 5.54e-41: 133: 93.90		Q32Q12_HUMAN (18-131): 3.16e-61: 192: 68.42
+	Hs
		548912 NDKA_HUMAN (1-82): 2.56e-40: 131: 80.49		Q32Q12_HUMAN (18-131): 3.16e-61: 192: 68.42