Protein: PHIP
PH-interacting protein (PHIP) (DDB1- and CUL4-associated factor 14) (IRS-1 PH domain-binding protein) (WD repeat-containing protein 11)

Gene: PHIP
Organism: Homo sapiens
Interactions: 192
UniProt ID: Q8WWQ0

Gene Ontology (top 5):
GO:0001932 - regulation of protein phosphorylation
GO:0005158 - insulin receptor binding
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0007010 - cytoskeleton organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1082298

DDB1
DNA damage-binding protein 1

10

20

Small-scale

0.967

High

1043124

CUL4A
Cullin-4A

11

20

Small-scale

0.755

High

1043478

CUL4B
Cullin-4B

8

20

Small-scale

0.750

High

935038

H31
Histone H3.1

4

20

Small-scale

0.676

High

211219

BUB3
Mitotic checkpoint protein BUB3

2

20

Small-scale

0.675

High

1067068

BRD3
Bromodomain-containing protein 3

1

20

High-throughput

0.665

High

772082

VHL
von Hippel-Lindau disease tumor suppressor

1

1

High-throughput

0.665

High

299434

UBXN7
UBX domain-containing protein 7

3

4

Small-scale

0.640

High

164439

TRI66
Tripartite motif-containing protein 66

1

20

High-throughput

0.618

High

244704

BRD4
Bromodomain-containing protein 4

1

20

High-throughput

0.618

High

600197

TAF1
Transcription initiation factor TFIID subunit 1

1

18

High-throughput

0.618

High

631525

BRD2
Bromodomain-containing protein 2

1

20

High-throughput

0.618

High

836257

TAF6
Transcription initiation factor TFIID subunit 6

1

5

High-throughput

0.618

High

847033

SMCA4
Transcription activator BRG1

1

20

Small-scale

0.618

High

1059760

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

20

Small-scale

0.618

High

1074799

TAF5
Transcription initiation factor TFIID subunit 5

1

16

High-throughput

0.618

High

1080166

EZH2
Histone-lysine N-methyltransferase EZH2

1

20

High-throughput

0.618

High

1123641

DCAF6
DDB1- and CUL4-associated factor 6

1

19

High-throughput

0.618

High

1139022

TAF3
Transcription initiation factor TFIID subunit 3

1

17

High-throughput

0.618

High

1164179

BRWD3
Bromodomain and WD repeat-containing protein 3

1

19

High-throughput

0.618

High

1199169

PB1
Protein polybromo-1

1

18

Small-scale

0.618

High

1255033

CHD5
Chromodomain-helicase-DNA-binding protein 5

1

20

Small-scale

0.618

High

1262796

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

20

Small-scale

0.618

High

1262802

RSF1
Remodeling and spacing factor 1

1

20

Small-scale

0.618

High

1262809

MEP50
Methylosome protein WDR77

1

17

Small-scale

0.618

High

1262811

CECR2
Chromatin remodeling regulator CECR2

1

20

High-throughput

0.618

High

1262819

WDR76
WD repeat-containing protein 76

1

17

High-throughput

0.618

High

996791

SSRP1
FACT complex subunit SSRP1

2

20

Small-scale

0.611

High

1061186

NUMA1
Nuclear mitotic apparatus protein 1

2

18

Small-scale

0.611

High

1085854

IF16
Gamma-interferon-inducible protein 16

2

8

High-throughput

0.611

High

1087293

H2B2E
Histone H2B type 2-E

2

17

Small-scale

0.611

High

524997

XRCC5
X-ray repair cross-complementing protein 5

2

2

Small-scale

0.584

High

952500

H33
Histone H3.3

2

20

Small-scale

0.584

High

1262849

SP16H
FACT complex subunit SPT16

2

7

Small-scale

0.584

High

828320

CENPA
Histone H3-like centromeric protein A

2

20

Small-scale

0.571

High

149109

CTRO
Citron Rho-interacting kinase

1

11

High-throughput

0.553

High

1171001

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.553

High

1244397

NUP43
Nucleoporin Nup43

1

19

High-throughput

0.553

High

1262818

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.553

High

1262823

ANLN
Anillin

1

6

High-throughput

0.553

High

557751

NCK1
SH2/SH3 adapter protein NCK1

1

8

High-throughput

0.536

High

564974

HMGA1
High mobility group protein HMG-I/HMG-Y

1

2

High-throughput

0.536

High

575510

EGR1
Early growth response protein 1

1

1

High-throughput

0.536

High

649630

RL10
Large ribosomal subunit protein uL16

1

3

High-throughput

0.536

High

786044

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

3

High-throughput

0.536

High

948822

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

1

4

High-throughput

0.536

High

1033394

ORC1
Origin recognition complex subunit 1

1

2

High-throughput

0.536

High

1153882

IFIX
Pyrin and HIN domain-containing protein 1

1

8

High-throughput

0.536

High

1262800

HDA11
Histone deacetylase 11

1

20

High-throughput

0.536

High

1262801

DCNL1
DCN1-like protein 1

1

1

High-throughput

0.536

High

1262805

MPP8
M-phase phosphoprotein 8

1

14

High-throughput

0.536

High

1262808

VRK1
Serine/threonine-protein kinase VRK1

1

8

High-throughput

0.536

High

1262815

NUCKS
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1

1

2

High-throughput

0.536

High

71194

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

15

High-throughput

0.515

High

360217

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

10

High-throughput

0.515

High

502368

BIP
Endoplasmic reticulum chaperone BiP

1

12

High-throughput

0.515

High

518903

TPR
Nucleoprotein TPR

1

20

High-throughput

0.515

High

1037324

TBB3
Tubulin beta-3 chain

1

20

High-throughput

0.481

High

124240

TAF4
Transcription initiation factor TFIID subunit 4

1

15

High-throughput

0.479

High

151436

CHD1
Chromodomain-helicase-DNA-binding protein 1

1

20

Small-scale

0.479

High

164247

ZN609
Zinc finger protein 609

1

10

High-throughput

0.479

High

167165

ZN536
Zinc finger protein 536

1

3

High-throughput

0.479

High

172484

NKRF
NF-kappa-B-repressing factor

1

3

High-throughput

0.479

High

178982

FOXP2
Forkhead box protein P2

1

20

High-throughput

0.479

High

210163

PRC1
Protein regulator of cytokinesis 1

1

15

High-throughput

0.479

High

229448

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

20

Small-scale

0.479

High

231131

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

3

High-throughput

0.479

High

231325

GANP
Germinal-center associated nuclear protein

1

10

High-throughput

0.479

High

233870

HBP1
HMG box-containing protein 1

1

20

High-throughput

0.479

High

237612

DIAP1
Protein diaphanous homolog 1

1

2

High-throughput

0.479

High

255950

OBSL1
Obscurin-like protein 1

1

11

High-throughput

0.479

High

257668

ANR17
Ankyrin repeat domain-containing protein 17

1

5

High-throughput

0.479

High

297651

RHBT1
Rho-related BTB domain-containing protein 1

1

16

High-throughput

0.479

High

313649

ZIC2
Zinc finger protein ZIC 2

1

2

High-throughput

0.479

High

347443

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.479

High

433921

LYN
Tyrosine-protein kinase Lyn

1

4

High-throughput

0.479

High

455699

PARP1
Poly [ADP-ribose] polymerase 1

1

12

High-throughput

0.479

High

470106

H2AZ
Histone H2A.Z

1

17

Small-scale

0.479

High

485137

GLI3
Transcriptional activator GLI3

1

2

High-throughput

0.479

High

553291

RFA2
Replication protein A 32 kDa subunit

1

6

High-throughput

0.479

High

603619

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

6

High-throughput

0.479

High

611472

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

20

High-throughput

0.479

High

651796

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.479

High

668856

PML
Protein PML

1

20

High-throughput

0.479

High

742432

SYUA
Alpha-synuclein

1

5

High-throughput

0.479

High

824223

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

16

High-throughput

0.479

High

848435

IRAK1
Interleukin-1 receptor-associated kinase 1

1

1

High-throughput

0.479

High

882461

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

13

High-throughput

0.479

High

897279

CSN2
COP9 signalosome complex subunit 2

1

5

Small-scale

0.479

High

904053

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

16

Small-scale

0.479

High

912338

SMD1
Small nuclear ribonucleoprotein Sm D1

1

16

Small-scale

0.479

High

916725

RS6
Small ribosomal subunit protein eS6

1

4

High-throughput

0.479

High

917657

H4
Histone H4

1

15

Small-scale

0.479

High

918554

H2B1C
Histone H2B type 1-C/E/F/G/I

1

17

High-throughput

0.479

High

969886

KIF23
Kinesin-like protein KIF23

1

12

High-throughput

0.479

High

974620

MECOM
Histone-lysine N-methyltransferase MECOM

1

6

High-throughput

0.479

High

1024193

CSN1
COP9 signalosome complex subunit 1

1

5

Small-scale

0.479

High

1027151

CBX3
Chromobox protein homolog 3

1

11

High-throughput

0.479

High

1035927

BIRC3
Baculoviral IAP repeat-containing protein 3

1

9

High-throughput

0.479

High

1042151

CUL3
Cullin-3

1

20

Small-scale

0.479

High

1066457

KIF14
Kinesin-like protein KIF14

1

13

High-throughput

0.479

High

1079551

NEDD8
NEDD8

1

6

Small-scale

0.479

High

1080554

ZFHX3
Zinc finger homeobox protein 3

1

7

High-throughput

0.479

High

1087066

H2A2C
Histone H2A type 2-C

1

13

Small-scale

0.479

High

1089538

CPEB4
Cytoplasmic polyadenylation element-binding protein 4

1

6

High-throughput

0.479

High

1158790

TAF2
Transcription initiation factor TFIID subunit 2

1

4

High-throughput

0.479

High

1163763

RICTR
Rapamycin-insensitive companion of mTOR

1

5

High-throughput

0.479

High

1167278

BCOR
BCL-6 corepressor

1

13

High-throughput

0.479

High

1173744

ACD11
Acyl-CoA dehydrogenase family member 11

1

1

High-throughput

0.479

High

1174607

H32
Histone H3.2

1

20

Small-scale

0.479

High

1184920

CSN6
COP9 signalosome complex subunit 6

1

2

Small-scale

0.479

High

1193136

SLN11
Schlafen family member 11

1

2

High-throughput

0.479

High

1199921

ZFHX4
Zinc finger homeobox protein 4

1

4

High-throughput

0.479

High

1217546

FOXP4
Forkhead box protein P4

1

19

High-throughput

0.479

High

1219298

PHF6
PHD finger protein 6

1

20

Small-scale

0.479

High

1221598

SMC5
Structural maintenance of chromosomes protein 5

1

4

High-throughput

0.479

High

1224378

XRN1
5'-3' exoribonuclease 1

1

4

High-throughput

0.479

High

1262794

CSN5
COP9 signalosome complex subunit 5

1

7

Small-scale

0.479

High

1262798

DCPS
m7GpppX diphosphatase

1

1

High-throughput

0.479

High

1262803

HTF4
Transcription factor 12

1

1

High-throughput

0.479

High

1262804

RING2
E3 ubiquitin-protein ligase RING2

1

19

High-throughput

0.479

High

1262807

PKP2
Plakophilin-2

1

16

High-throughput

0.479

High

1262810

CSN4
COP9 signalosome complex subunit 4

1

1

Small-scale

0.479

High

1262812

RHBT2
Rho-related BTB domain-containing protein 2

1

16

High-throughput

0.479

High

1262813

BC11B
B-cell lymphoma/leukemia 11B

1

1

High-throughput

0.479

High

1262816

FOXP1
Forkhead box protein P1

1

15

High-throughput

0.479

High

1262820

AGO3
Protein argonaute-3

1

1

High-throughput

0.479

High

1262821

CSN7B
COP9 signalosome complex subunit 7b

1

2

Small-scale

0.479

High

1262822

PRD16
Histone-lysine N-methyltransferase PRDM16

1

5

High-throughput

0.479

High

1262824

4ET
Eukaryotic translation initiation factor 4E transporter

1

1

High-throughput

0.479

High

1262825

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

7

High-throughput

0.479

High

1262826

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

3

High-throughput

0.479

High

1262827

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

3

High-throughput

0.479

High

1262828

RCOR3
REST corepressor 3

1

18

High-throughput

0.479

High

1262829

MYEF2
Myelin expression factor 2

1

5

High-throughput

0.479

High

1262830

RERE
Arginine-glutamic acid dipeptide repeats protein

1

14

High-throughput

0.479

High

1262831

HDAC6
Histone deacetylase 6

1

20

High-throughput

0.479

High

1262832

CSN7A
COP9 signalosome complex subunit 7a

1

2

Small-scale

0.479

High

1262834

TBK1
Serine/threonine-protein kinase TBK1

1

8

High-throughput

0.479

High

1262835

TRPS1
Zinc finger transcription factor Trps1

1

17

High-throughput

0.479

High

1262836

RCOR1
REST corepressor 1

1

19

High-throughput

0.479

High

1262837

AGO2
Protein argonaute-2

1

1

High-throughput

0.479

High

1262839

INT6
Integrator complex subunit 6

1

2

High-throughput

0.479

High

1262840

ZN608
Zinc finger protein 608

1

7

High-throughput

0.479

High

1262841

CIZ1
Cip1-interacting zinc finger protein

1

6

High-throughput

0.479

High

1262842

AKP8L
A-kinase anchor protein 8-like

1

3

High-throughput

0.479

High

1262843

CSN3
COP9 signalosome complex subunit 3

1

5

Small-scale

0.479

High

1262846

SRRM2
Serine/arginine repetitive matrix protein 2

1

19

High-throughput

0.479

High

1262847

ZN281
Zinc finger protein 281

1

2

High-throughput

0.479

High

1262848

ZN330
Zinc finger protein 330

1

1

High-throughput

0.479

High

1262850

NCOR2
Nuclear receptor corepressor 2

1

20

High-throughput

0.479

High

1262851

IF2B2
Insulin-like growth factor 2 mRNA-binding protein 2

1

17

High-throughput

0.479

High

500846

CLUS
Clusterin

1

0

High-throughput

0.458

High

1262791

CSN9
COP9 signalosome complex subunit 9

1

0

Small-scale

0.458

High

1262792

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.458

High

1262806

CSN8
COP9 signalosome complex subunit 8

1

0

Small-scale

0.458

High

1262845

SATB2
DNA-binding protein SATB2

1

0

Small-scale

0.458

High

381255

TBB4A
Tubulin beta-4A chain

1

20

High-throughput

0.457

High

179745

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

5

High-throughput

0.437

High

322927

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

14

High-throughput

0.437

High

398381

PCCB
Propionyl-CoA carboxylase beta chain, mitochondrial

1

16

High-throughput

0.437

High

506014

ODB2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

1

5

High-throughput

0.437

High

575803

VINC
Vinculin

1

2

Small-scale

0.437

High

612036

HEMH
Ferrochelatase, mitochondrial

1

1

High-throughput

0.437

High

721020

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.437

High

963378

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

10

Small-scale

0.437

High

1057839

GSE1
Genetic suppressor element 1

1

1

High-throughput

0.437

High

1061027

NOLC1
Nucleolar and coiled-body phosphoprotein 1

1

16

Small-scale

0.437

High

1061519

CUL7
Cullin-7

1

7

High-throughput

0.437

High

1121681

SWAHC
Ankyrin repeat domain-containing protein SOWAHC

1

6

High-throughput

0.437

High

1131785

CE170
Centrosomal protein of 170 kDa

1

19

High-throughput

0.437

High

1135879

TUT4
Terminal uridylyltransferase 4

1

5

High-throughput

0.437

High

1219797

ANKH1
Ankyrin repeat and KH domain-containing protein 1

1

5

High-throughput

0.437

High

1230151

CNTRB
Centrobin

1

12

High-throughput

0.437

High

1235575

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

4

High-throughput

0.437

High

1242611

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

14

High-throughput

0.437

High

1262793

LAR4B
La-related protein 4B

1

7

High-throughput

0.437

High

1262795

GCDH
Glutaryl-CoA dehydrogenase, mitochondrial

1

1

High-throughput

0.437

High

1262797

CHCH1
Small ribosomal subunit protein mS37

1

1

High-throughput

0.437

High

1262799

CHM4C
Charged multivesicular body protein 4c

1

7

High-throughput

0.437

High

1262833

MKRN1
E3 ubiquitin-protein ligase makorin-1

1

3

High-throughput

0.437

High

1262838

NUP50
Nuclear pore complex protein Nup50

1

6

High-throughput

0.437

High

1262844

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

7

High-throughput

0.437

High

1047178

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

1

High-throughput

0.407

High

1262817

TXNIP
Thioredoxin-interacting protein

1

3

High-throughput

0.407

High

1262814

STMN4
Stathmin-4

1

0

High-throughput

0.282

High

1241215

NECP1
Adaptin ear-binding coat-associated protein 1

1

0

High-throughput

0.279

Low

166289

GRRE1
Granule associated Rac and RHOG effector protein 1

1

0

High-throughput

0.249

Low

343996

ASSY
Argininosuccinate synthase

1

0

High-throughput

0.249

Low

520728

ODBA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low

1229820

SPICE
Spindle and centriole-associated protein 1

1

0

High-throughput

0.249

Low

1246610

COQ8A
Atypical kinase COQ8A, mitochondrial

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024