HitPredict

Interactor 1: RNF4 (P78317)
E3 ubiquitin-protein ligase RNF4 (EC 2.3.2.27) (RING finger protein 4) (Small nuclear ring finger protein) (Protein SNURF)
Gene: RNF4

Interactor 2: VEZF1 (Q14119)
Vascular endothelial zinc finger 1 (Putative transcription factor DB1) (Zinc finger protein 161)
Gene: VEZF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29180619
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0008270 - zinc ion binding GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 190 Hs			1 521
+	Hs
		1005016 RNF4_HUMAN (1-190): 9.74e-53: 168: 100.00		ZN184_HUMAN (41-498): 0: 585: 16.40
+	Hs
		1004865 RNF4_HUMAN (1-190): 9.74e-53: 168: 100.00		ZN420_HUMAN (55-513): 0: 541: 16.77
+	Hs
		1004687 RNF4_HUMAN (1-190): 9.74e-53: 168: 100.00		ZN658_HUMAN (29-498): 1.57e-118: 375: 10.65
+	Hs
		1004970 RNF4_HUMAN (1-190): 9.74e-53: 168: 100.00		ZN845_HUMAN (57-498): 4.06e-114: 362: 16.17
+	Hs
		599935 RNF4_HUMAN (1-190): 9.74e-53: 168: 100.00		ZNF12_HUMAN (43-470): 5.87e-117: 362: 16.77
+	Hs
		295024 RNF4_HUMAN (1-190): 9.74e-53: 168: 100.00		ZN189_HUMAN (106-470): 9.56e-106: 331: 17.87
+	Hs
		599985 RNF4_HUMAN (1-190): 9.74e-53: 168: 100.00		ZNF16_HUMAN (2-258): 8.45e-100: 317: 19.77
+	Hs
		1004829 RNF4_HUMAN (1-190): 9.74e-53: 168: 100.00		ZN283_HUMAN (9-296): 1.09e-86: 282: 18.62
+	Hs
		940378 RNF4_HUMAN (1-190): 9.74e-53: 168: 100.00		MAZ_HUMAN (66-327): 2.94e-81: 263: 54.34
+	Hs
		1005112 RNF4_HUMAN (1-190): 9.74e-53: 168: 100.00		PATZ1_HUMAN (148-324): 1.02e-65: 227: 58.10
+	Hs
		1004784 RNF4_HUMAN (1-190): 9.74e-53: 168: 100.00		ZN227_HUMAN (270-512): 2.3e-63: 222: 8.41
+	Hs
		1005071 RNF4_HUMAN (1-190): 9.74e-53: 168: 100.00		ZN436_HUMAN (188-432): 7.9e-64: 216: 21.51
+	Hs
		1005117 RNF4_HUMAN (1-190): 9.74e-53: 168: 100.00		ZN160_HUMAN (326-499): 6.81e-41: 159: 9.47
+	Hs
		70556 RNF4_HUMAN (1-190): 9.74e-53: 168: 100.00		ZN850_HUMAN (399-507): 1.51e-19: 94.8: 9.17
+	Hs
		1005210 RNF4_HUMAN (1-190): 9.74e-53: 168: 100.00		ZN629_HUMAN (3-228): 4.97e-17: 86.5: 14.09
+	Hs
		1005178 RNF4_HUMAN (1-190): 9.74e-53: 168: 100.00		RBAK_HUMAN (68-324): 1.05e-16: 85.5: 28.03
+	Hs
		1004614 RNF4_HUMAN (1-190): 9.74e-53: 168: 100.00		ZKSC8_HUMAN (45-143): 1.97e-16: 84.3: 14.78
+	Hs
		600476 RNF4_HUMAN (1-190): 9.74e-53: 168: 100.00		ZNF28_HUMAN (171-319): 2.43e-15: 80.9: 30.92
+	Hs
		1004835 RNF4_HUMAN (1-190): 9.74e-53: 168: 100.00		ZFP62_HUMAN (2-71): 1.02e-14: 79.4: 1.43
+	Hs
		60183 RNF4_HUMAN (1-190): 9.74e-53: 168: 100.00		ZN320_HUMAN (190-326): 5.61e-12: 70.1: 33.57