Protein: ZKSC8
Zinc finger protein with KRAB and SCAN domains 8 (LD5-1) (Zinc finger protein 192)

Gene: ZKSC8, ZKSCAN8
Organism: Homo sapiens
Interactions: 160
UniProt ID: Q15776

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1153640

ZN444
Zinc finger protein 444

5

20

High-throughput

0.926

High

1153658

ZN396
Zinc finger protein 396

4

20

High-throughput

0.892

High

600546

ZSC20
Zinc finger and SCAN domain-containing protein 20

3

18

High-throughput

0.861

High

1153644

ZN397
Zinc finger protein 397

3

19

High-throughput

0.861

High

1153674

ZSC32
Zinc finger and SCAN domain-containing protein 32

3

20

High-throughput

0.861

High

171883

ZN263
Zinc finger protein 263

2

18

High-throughput

0.811

High

1133373

ZN169
Zinc finger protein 169

2

20

High-throughput

0.811

High

1153633

Z324B
Zinc finger protein 324B

2

20

High-throughput

0.811

High

1153648

ZN483
Zinc finger protein 483

2

19

High-throughput

0.811

High

1153652

ZKSC4
Zinc finger protein with KRAB and SCAN domains 4

2

19

High-throughput

0.811

High

1153656

PGBD1
PiggyBac transposable element-derived protein 1

2

20

High-throughput

0.811

High

1153685

ZN232
Zinc finger protein 232

2

19

High-throughput

0.811

High

600308

ZNF24
Zinc finger protein 24

2

20

Small-scale

0.793

High

1152362

ZN174
Zinc finger protein 174

2

20

Small-scale

0.793

High

1153661

ZN587
Zinc finger protein 587

2

18

High-throughput

0.783

High

60190

ZN320
Zinc finger protein 320

1

18

High-throughput

0.691

High

163502

ZN213
Zinc finger protein 213

1

20

High-throughput

0.691

High

193855

ZSC9
Zinc finger and SCAN domain-containing protein 9

1

20

High-throughput

0.691

High

245030

ZN500
Zinc finger protein 500

1

18

High-throughput

0.691

High

517768

GLI4
Zinc finger protein GLI4

1

20

High-throughput

0.691

High

599957

ZN708
Zinc finger protein 708

1

11

High-throughput

0.691

High

600421

ZKSC1
Zinc finger protein with KRAB and SCAN domains 1

1

19

High-throughput

0.691

High

944180

SCND1
SCAN domain-containing protein 1

1

20

High-throughput

0.691

High

946048

ZN121
Zinc finger protein 121

1

17

High-throughput

0.691

High

948201

ZN445
Zinc finger protein 445

1

15

High-throughput

0.691

High

1044414

ZNF92
Zinc finger protein 92

1

11

High-throughput

0.691

High

1051150

ZNF91
Zinc finger protein 91

1

10

High-throughput

0.691

High

1153628

ZSC26
Zinc finger and SCAN domain-containing protein 26

1

19

High-throughput

0.691

High

1153629

ZSC23
Zinc finger and SCAN domain-containing protein 23

1

19

High-throughput

0.691

High

1153634

ZSC25
Zinc finger and SCAN domain-containing protein 25

1

19

High-throughput

0.691

High

1153637

ZN467
Zinc finger protein 467

1

20

High-throughput

0.691

High

1153647

ZSC18
Zinc finger and SCAN domain-containing protein 18

1

20

High-throughput

0.691

High

1153655

ZN496
Zinc finger protein 496

1

20

High-throughput

0.691

High

1153657

ZN668
Zinc finger protein 668

1

12

High-throughput

0.691

High

1153664

ZKSC3
Zinc finger protein with KRAB and SCAN domains 3

1

19

High-throughput

0.691

High

1153673

ZN446
Zinc finger protein 446

1

20

High-throughput

0.691

High

1153677

ZN629
Zinc finger protein 629

1

11

High-throughput

0.691

High

1153680

ZN215
Zinc finger protein 215

1

19

High-throughput

0.691

High

1153692

ZSC21
Zinc finger and SCAN domain-containing protein 21

1

19

High-throughput

0.691

High

890656

RGS3
Regulator of G-protein signaling 3

3

3

High-throughput

0.662

High

1088368

CHD3
Chromodomain-helicase-DNA-binding protein 3

3

3

High-throughput

0.656

High

892401

ZN165
Zinc finger protein 165

1

19

Small-scale

0.621

High

1153626

ZKSC8
Zinc finger protein with KRAB and SCAN domains 8

1

19

Small-scale

0.621

High

978965

RS6
Small ribosomal subunit protein eS6

2

4

High-throughput

0.611

High

1132718

CHD4
Chromodomain-helicase-DNA-binding protein 4

2

3

High-throughput

0.611

High

1153675

ZMYM2
Zinc finger MYM-type protein 2

2

13

High-throughput

0.611

High

898672

RL14
Large ribosomal subunit protein eL14

3

3

High-throughput

0.609

High

961037

MGN
Protein mago nashi homolog

2

3

High-throughput

0.606

High

1150100

TCEA2
Transcription elongation factor A protein 2

2

1

High-throughput

0.606

High

191657

MAGB2
Melanoma-associated antigen B2

2

3

High-throughput

0.601

High

998357

H31
Histone H3.1

2

13

High-throughput

0.584

High

1099931

TIF1B
Transcription intermediary factor 1-beta

2

20

Small-scale

0.584

High

71013

ZN724
Zinc finger protein 724

1

11

High-throughput

0.575

High

1153660

SRPK1
SRSF protein kinase 1

1

11

High-throughput

0.575

High

1153630

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

2

10

High-throughput

0.574

High

182304

WDR46
WD repeat-containing protein 46

2

9

High-throughput

0.558

High

569246

YJU2B
Probable splicing factor YJU2B

2

5

High-throughput

0.549

High

809652

RS19
Small ribosomal subunit protein eS19

2

3

High-throughput

0.549

High

286999

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

20

High-throughput

0.536

High

338845

CBX6
Chromobox protein homolog 6

1

20

High-throughput

0.536

High

428784

RLA0
Large ribosomal subunit protein uL10

1

3

High-throughput

0.536

High

451513

CENPB
Major centromere autoantigen B

1

6

High-throughput

0.536

High

586714

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.536

High

615806

RL17
Large ribosomal subunit protein uL22

1

6

High-throughput

0.536

High

658198

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.536

High

913500

KIF11
Kinesin-like protein KIF11

1

3

High-throughput

0.536

High

987042

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

3

High-throughput

0.536

High

1047554

NOTC2
Neurogenic locus notch homolog protein 2

1

20

High-throughput

0.536

High

1111410

DGKZ
Diacylglycerol kinase zeta

1

1

High-throughput

0.536

High

1148691

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

3

High-throughput

0.536

High

1153632

ZMYM1
Zinc finger MYM-type protein 1

1

16

High-throughput

0.536

High

1153635

DHX57
Putative ATP-dependent RNA helicase DHX57

1

4

High-throughput

0.536

High

1153638

FBX11
F-box only protein 11

1

3

High-throughput

0.536

High

1153639

CUL9
Cullin-9

1

15

High-throughput

0.536

High

1153649

HNRLL
Heterogeneous nuclear ribonucleoprotein L-like

1

1

High-throughput

0.536

High

1153650

FGF13
Fibroblast growth factor 13

1

8

High-throughput

0.536

High

1153670

ECT2
Protein ECT2

1

1

High-throughput

0.536

High

1153672

ABC3C
DNA dC->dU-editing enzyme APOBEC-3C

1

5

High-throughput

0.536

High

1153679

ZN346
Zinc finger protein 346

1

2

High-throughput

0.536

High

1153683

ABT1
Activator of basal transcription 1

1

3

High-throughput

0.536

High

1153687

YBOX2
Y-box-binding protein 2

1

7

High-throughput

0.536

High

385779

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

20

High-throughput

0.515

High

767219

MERL
Merlin

1

1

High-throughput

0.515

High

843588

HD
Huntingtin

1

7

High-throughput

0.515

High

966354

1433G
14-3-3 protein gamma

1

9

High-throughput

0.515

High

1139716

SETB1
Histone-lysine N-methyltransferase SETDB1

1

7

High-throughput

0.515

High

1153645

LMO3
LIM domain only protein 3

1

12

High-throughput

0.515

High

1153651

KAT5
Histone acetyltransferase KAT5

1

1

High-throughput

0.515

High

1153688

RNF11
RING finger protein 11

1

1

High-throughput

0.515

High

337353

PARN
Poly(A)-specific ribonuclease PARN

1

0

High-throughput

0.513

High

959800

RS3A
Small ribosomal subunit protein eS1

1

0

High-throughput

0.513

High

1153653

THA11
THAP domain-containing protein 11

1

0

High-throughput

0.513

High

1153662

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

1

0

High-throughput

0.513

High

1153669

ADNP
Activity-dependent neuroprotector homeobox protein

1

0

High-throughput

0.513

High

185728

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

6

High-throughput

0.501

High

986449

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

0

High-throughput

0.493

High

287562

LRP6
Low-density lipoprotein receptor-related protein 6

1

9

High-throughput

0.489

High

301068

RL1D1
Ribosomal L1 domain-containing protein 1

1

5

High-throughput

0.489

High

334417

SYFM
Phenylalanine--tRNA ligase, mitochondrial

1

1

High-throughput

0.489

High

657246

KALM
Anosmin-1

1

10

High-throughput

0.489

High

969882

RS16
Small ribosomal subunit protein uS9

1

8

High-throughput

0.489

High

1011617

RT35
Small ribosomal subunit protein mS35

1

1

High-throughput

0.489

High

1011802

RT05
Small ribosomal subunit protein uS5m

1

2

High-throughput

0.489

High

1012845

RT09
Small ribosomal subunit protein uS9m

1

8

High-throughput

0.489

High

1016024

RL19
Large ribosomal subunit protein eL19

1

4

High-throughput

0.489

High

1099368

SRSF6
Serine/arginine-rich splicing factor 6

1

14

High-throughput

0.489

High

1122240

SCRIB
Protein scribble homolog

1

4

High-throughput

0.489

High

1127391

FGFP1
Fibroblast growth factor-binding protein 1

1

6

High-throughput

0.489

High

1134913

CUL7
Cullin-7

1

10

High-throughput

0.489

High

1151118

OASL
2'-5'-oligoadenylate synthase-like protein

1

4

High-throughput

0.489

High

1153641

FBXW8
F-box/WD repeat-containing protein 8

1

5

High-throughput

0.489

High

1153654

RT24
Small ribosomal subunit protein uS3m

1

2

High-throughput

0.489

High

1153666

YTHD1
YTH domain-containing family protein 1

1

1

High-throughput

0.489

High

1153671

DDX21
Nucleolar RNA helicase 2

1

5

High-throughput

0.489

High

1153686

RT07
Small ribosomal subunit protein uS7m

1

1

High-throughput

0.489

High

1153689

RT18C
Small ribosomal subunit protein bS18m

1

1

High-throughput

0.489

High

1153691

RL36
Large ribosomal subunit protein eL36

1

10

High-throughput

0.489

High

1153690

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

241786

PRKN
E3 ubiquitin-protein ligase parkin

1

17

High-throughput

0.479

High

406223

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

472764

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

2

High-throughput

0.479

High

810125

RL3
Large ribosomal subunit protein uL3

1

5

High-throughput

0.479

High

904767

MECP2
Methyl-CpG-binding protein 2

1

3

High-throughput

0.479

High

979723

H4
Histone H4

1

4

High-throughput

0.479

High

1004614

RNF4
E3 ubiquitin-protein ligase RNF4

1

16

High-throughput

0.479

High

1113197

CUL3
Cullin-3

1

20

High-throughput

0.479

High

1153646

LNX1
E3 ubiquitin-protein ligase LNX

1

6

Small-scale

0.479

High

1153659

CIC
Protein capicua homolog

1

5

High-throughput

0.479

High

1153667

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

5

High-throughput

0.479

High

1153678

XPO7
Exportin-7

1

9

High-throughput

0.479

High

109408

G5E9A7
DM1 locus, WD repeat containing

1

7

High-throughput

0.470

High

245950

KIF1B
Kinesin-like protein KIF1B

1

3

High-throughput

0.470

High

301435

WFS1
Wolframin

1

2

High-throughput

0.470

High

451165

NFL
Neurofilament light polypeptide

1

10

High-throughput

0.470

High

686618

ELAV4
ELAV-like protein 4

1

2

High-throughput

0.470

High

705351

GRN
Progranulin

1

2

High-throughput

0.470

High

954481

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

1

High-throughput

0.470

High

1153636

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

10

High-throughput

0.470

High

105992

APRIO
Alternative prion protein

1

4

Small-scale

0.457

High

422162

A4
Amyloid-beta precursor protein

1

15

High-throughput

0.457

High

1037168

H11
Histone H1.1

1

12

High-throughput

0.445

High

1153627

SRSF7
Serine/arginine-rich splicing factor 7

1

5

High-throughput

0.445

High

1153668

TGIF2
Homeobox protein TGIF2

1

1

High-throughput

0.445

High

1153642

KDF1
Keratinocyte differentiation factor 1

1

1

High-throughput

0.437

High

1153682

HECD1
E3 ubiquitin-protein ligase HECTD1

1

11

High-throughput

0.437

High

1153684

RL26L
Ribosomal protein uL24-like

1

5

High-throughput

0.437

High

285667

BAF
Barrier-to-autointegration factor

1

0

High-throughput

0.426

High

72778

B0UZZ8
WD repeat-containing protein 46

1

9

High-throughput

0.407

High

288658

NPM3
Nucleoplasmin-3

1

8

High-throughput

0.407

High

860762

RS10
Small ribosomal subunit protein eS10

1

4

High-throughput

0.407

High

1153665

S4A5
Electrogenic sodium bicarbonate cotransporter 4

1

1

High-throughput

0.407

High

1153676

SL9A2
Sodium/hydrogen exchanger 2

1

6

High-throughput

0.407

High

1153681

S39AA
Zinc transporter ZIP10

1

4

High-throughput

0.407

High

1012190

RT11
Small ribosomal subunit protein uS11m

1

0

High-throughput

0.279

Low

1012323

RT15
Small ribosomal subunit protein uS15m

1

0

High-throughput

0.279

Low

1153643

NOA1
Nitric oxide-associated protein 1

1

0

High-throughput

0.279

Low

1153631

Q5SUL5
HLA class I histocompatibility antigen A alpha chain

1

0

High-throughput

0.268

Low

404805

PRIO
Major prion protein

1

0

Small-scale

0.261

Low

1153663

PYM1
Partner of Y14 and mago

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025