Interactor 1: GPC5 (P78333)
Glypican-5 [Cleaved into: Secreted glypican-5]
Gene: GPC5

Interactor 2: PGBM (P98160)
Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) (Perlecan) (PLC) [Cleaved into: Endorepellin; LG3 peptide]
Gene: HSPG2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Glypican~I-set
Common GO terms GO:0005576 - extracellular region
GO:0005796 - Golgi lumen
GO:0005886 - plasma membrane
GO:0043202 - lysosomal lumen
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 572
Hs

1 4391
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 11Aug2025