HitPredict

Interactor 1: PRAME (P78395)
Melanoma antigen preferentially expressed in tumors (Opa-interacting protein 4) (OIP-4) (Preferentially expressed antigen of melanoma)
Gene: PRAME

Interactor 2: ELOB (Q15370)
Elongin-B (EloB) (Elongin 18 kDa subunit) (RNA polymerase II transcription factor SIII subunit B) (SIII p18) (Transcription elongation factor B polypeptide 2)
Gene: ELOB

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.708

Property	Details
Experiments	21822215, 22912744, 23460923, 31253590
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0031462 - Cul2-RING ubiquitin ligase complex
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 509 Hs			1 118
+	Hs
		256550 PRAM2_HUMAN (18-504): 6.92e-147: 431: 42.71		ELOB_HUMAN (1-118): 1.64e-66: 198: 100.00
+	Hs
		1139891 LRC14_HUMAN (25-483): 2.88e-91: 288: 30.29		ELOB_HUMAN (1-118): 1.64e-66: 198: 100.00
+	Hs
		1147194 NLRC3_HUMAN (272-495): 4.89e-10: 64.3: 18.75		ELOB_HUMAN (1-118): 1.64e-66: 198: 100.00